Browsing by Author "González, Leticia"

Now showing items 1-4 of 4

    • Angiotensin-(1-9) reduces cardiovascular and renal inflammation in experimental renin-independent hypertension 
      González, Leticia; Novoa, Ulises; Moya, Jackeline; Gabrielli, Luigi; Jalil Milad, Jorge; García Nannig, Lorena; Chiong Lay, Mario; Lavandero González, Sergio; Ocaranza, María Paz (Elsevier Inc., 2018)
      © 2018 Elsevier Inc. Hypertension-induced cardiovascular and renal damage can be mediated by activation of the renin-angiotensin-aldosterone system. There are different factors beyond renin-angiotensin-aldosterone system ...
    • Rho kinase inhibition activates the homologous angiotensin-converting enzyme-angiotensin-(1-9) axis in ... 
      Ocaranza, María Paz; Rivera, Paulina; Novoa, Ulises; Pinto, Melissa; González, Leticia; Chiong Lay, Mario; Lavandero González, Sergio; Jalil Milad, Jorge (LIPPINCOTT WILLIAMS & WILKINS, 2011-04)
      Background Angiotensin II (Ang II) levels depend on renin, angiotensin-converting enzyme (ACE), and on the homologous angiotensin-converting enzyme (ACE2). Increased ACE and Ang II levels are associated with higher Rho ...
    • Serum uric acid correlates with extracellular superoxide dismutase activity in patients with chronic heart failure 
      Alcaíno Gálvez, Hernán Alejandro; Greig, Douglas; Chiong Lay, Mario; Verdejo, Hugo; Miranda, Rodrigo; Concepción, Roberto; Vukasovic Ramírez, José Luis; Díaz Araya, Guillermo; Mellado, Rose Marie; García Nannig, Lorena; Salas, Daniela; González, Leticia; Godoy, Iván; Castro, Pablo; Lavandero González, Sergio (ELSEVIER, 2008-07)
      Increased serum uric acid has been identified as an independent risk factor for cardiovascular disease. However, because of its antioxidant capacity, uric acid may play a beneficial role in endothelial function. This ...
    • The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling 
      Muñoz, Juan Pablo; Collao, Andrés; Chiong Lay, Mario; Maldonado Vera, Carola Patricia; Adasme, Tatiana; Carrasco Alarcón, Loreto del Pilar; Ocaranza Osses, Paula; Bravo Méndez, Roberto; González, Leticia; Díaz Araya, Guillermo; Hidalgo Tapia, María Cecilia; Lavandero González, Sergio (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2009-10-09)
      Myocyte enhancer factor 2C (MEF2C) plays an important role in cardiovascular development and is a key transcription factor for cardiac hypertrophy. Here, we describe MEF2C regulation by insulin-like growth factor-1 (IGF-1) ...