Browsing by Author "Peredo Silva, Liliana"

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    • Microsomal oxidative damage promoted by acetaminophen metabolism 
      Letelier Muñoz, María Eugenia; López Valladares, Miguel; Peredo Silva, Liliana; Rojas Sepúlveda, Daniel; Aracena, Paula (PERGAMON-ELSEVIER SCIENCE LTD., 2011-10)
      Adverse reactions of acetaminophen have been associated to oxidative stress, which may be elicited by reactive oxygen species (ROS) and/or production of the metabolite NAPQI. Both phenomena would arise through the activity ...
    • A protocol for evaluating the safety of herbal preparations in a rat model: the case of a supercritical ... 
      Letelier Muñoz, María Eugenia; Aracena Parks, Paula; Peredo Silva, Liliana (2010)
      Herbal extracts must be evaluated for their efficacy and safety. In vivo acute toxicity studies must consider the different mechanisms by which active compounds may elicit toxicological outcomes. Thus, a methodology to ...