Now showing items 98-117 of 854

    • Cáceres, Mónica; Tobar, Nicolás; Guerrero, Javier; Smith, Patricio C.; Martínez, Jorge (WILEY-LISS, DIV JOHN WILEY & SONS INC, 2008-02-15)
      In this study, we demonstrated that tyrosine phosphorylation of EGFR and the autocrine expression of uPA and HB-EGF depend on the activity of c-jun amino-terminal kinase (JNK) in human prostatic DU-145 cells. These cells ...
    • Cifuentes, Mariana; Fuentes, Cecilia; Tobar, Nicolás; Acevedo, Ingrid; Villalobos, Elisa; Hugo, Eric; Ben-Jonathan, Nira; Reyes Jedlicki, Marcela (Elsevier, 2012)
      The proinflammatory status of adipose tissue has been linked to the metabolic and cardiovascular consequences of obesity. Human adipose cells express the calcium sensing receptor (CaSR), and its expression is elevated ...
    • D'Espessailles Tapia, Amanda; Santillana, Natalia; Sanhueza, Sofía; Fuentes, Cecilia; Cifuentes Koster, Mariana (Elsevier, 2020)
      Excess adipose tissue (AT) associates with inflammation and obesity-related diseases. We studied whether calcium-sensing receptor (CaSR)-mediated NLRP3 inflammasome activation in THP-1 macrophages elevates inflammation in ...
    • Villarroel, Pía; Espessailles, Amanda D.; Arrese, Marco; Cifuentes, Mariana (Wiley, 2016)
    • Bravo Sagua, Roberto; Mattar, Pamela; Díaz, Ximena; Lavandero González, Sergio; Cifuentes, Mariana (Frontiers Media, 2016)
      Obesity is currently a serious worldwide public health problem, reaching pandemic levels. For decades, dietary and behavioral approaches have failed to prevent this disease from expanding, and health authorities are ...
    • Villarroel, Pía; Mattar, Pamela; D'Espessailles Tapia, Amanda; Arrese, Marco; Arreguin, Andrea; Fuentes, Cecilia; Reyes, Marcela; Cifuentes, Mariana (2016)
      The calcium sensing receptor (CaSR) is expressed in human adipose cells, and its activation may associate with adipose tissue (AT) dysfunction. We evaluated whether CaSR stimulation influences adipocyte triglyceride (TG) ...
    • D'Espessailles Tapia, Amanda; Mora, Yuly A.; Fuentes, Cecilia; Cifuentes, Mariana (Wiley, 2018)
      The study of the mechanisms that trigger inflammation in adipose tissue is key to understanding and preventing the cardiometabolic consequences of obesity. We have proposed a model where activation of the G protein-coupled ...
    • Mattar, Pamela; Pino Sanhueza, Sofía Carolina; Yuri, Gabriela; Briones, Lautaro; Pérez Leighton, Claudio; Rudich, Assaf; Lavandero González, Sergio; Cifuentes Koster, Mariana (MDPI, 2020)
      Autophagy is upregulated in adipose tissue (AT) from people with obesity. We showed that activation of the calcium-sensing receptor (CaSR) elevates proinflammatory cytokines through autophagy in preadipocytes. Our aim is ...
    • Luque, Cecilia; Cisternas, Felipe A.; Araya, Magdalena (2006)
      Background: During the twentieth century there was a change in the pattern of diseases in Europe, with an increase in the incidence of allergies and autoimmune disorders, that paralleled a decrease of infectious conditions. ...
    • Crovetto, Mirta; Uauy Dagach-Imbarack, Ricardo (ARCHIVOS LATINOAMERICANOS NUTRICION, 2008-03)
      Changes in household food availability from 1988-1997 obtained in a representative sample of Metropolitan Santiago were assessed; and related to observed changes in the epidemiological profile. We evaluated expenditures ...
    • Time, Alson; Ponce, Claudio; Kuhn, Nathalie; Arellano, Macarena; Sagredo, Boris; Donoso, José Manuel; Meisel, Lee Ann (MDPI, 2021)
      Abscisic acid (ABA) plays a major role in promoting ripening in sweet cherry, a non-climacteric fruit. Exogenous application of ABA has been performed to study fruit ripening and cracking, but this growth regulator is not ...
    • Alliende Rodríguez, María Angélica; Curotto, Bianca; Guerra, Patricio; Santa María, Lorena; Hermosilla, Reinería; Orphanópoulos, Doris; Villanueva, Jorge; Wettig, Elizabeth; Barraza, Ximena (2011)
      Background: Chromosome aberrations (CA) are the main etiology of multiple congenital malformations, recurrent abortions and intellectual disability (ID) specifi cally of moderate and severe degree. They account for 0.3 ...
    • Reyes J., Marcela (2010-12)
    • Zepeda Iriarte, Ramiro; Castillo, Paula; Sáez, Daniel; Llanos Silva, Miguel; Ronco Macchiavello, Ana María (Springer, 2012)
      It has been suggested that prenatal exposure to cadmium may alter the cardiovascular function during adulthood. Using the left coronary artery ligation model of acute myocardial infarction, we studied the cardiac ...
    • Gunning, Marlise N.; Sir Petermann, Teresa; Crisosto King, Nicolás; van Rijn, Bas B.; de Wilde, Marlieke A.; Christ, Jacob P.; Uiterwaal, C. S. P. M.; de Jager, Wilco; Eijkemans, Marinus J. C.; Kunselman, Allen R.; Legro, Richard S.; Fauser, Bart C. J. M. (Oxford Unv Press, 2020)
      BACKGROUND: Women diagnosed with polycystic ovary syndrome (PCOS) suffer from an unfavorable cardiometabolic risk profile, which is already established by child-bearing age. OBJECTIVE AND RATIONALE: The aim of this ...
    • Correa Burrows, María Paulina; Rodríguez Letelier, Yanina; Blanco, Estela; Gahagan, S.; Burrows, Raquel (Karger, 2016)
    • Correa Burrows, María Paulina; Rodríguez, Yanina; Blanco, Estela; Gahagan, Sheila; Burrows, Raquel (Karger, 2017)
    • Barrera Acevedo, María; Bunout Barnett, Daniel; Maza Cave, María Pía de la; Leiva Balich, Laura; Hirsch Birn, Sandra (Japan Geriatrics Society, 2014)
      Aim: To explore the usefulness of carotid ultrasound examination as a marker of aging and predictor of disability among older people. Methods: Carotid ultrasound, measuring carotid intima media thickness (CIMT) and ...
    • Kaput, Jim; Ordovas, José; Ferguson, Lynnette; Van Ommen, Ben; Rodríguez, Raymond; Allen, Lindsay; Ames, Bruce; Dawson, Kevin; German, Bruce; Krauss, Roland; Malyj, Wasyl; Archer, Michael; Barnes, Stephen; Bartholomew, Amelia; Birk, Ruth; Van Bladeren, Peter; Bradford, Kent; Brown, Kenneth; Caetano, Rosane; Castle, David; Chadwick, Ruth; Clarke, Stephen; Clément, Karine; Cooney, Craig; Corella, Dolores; Manica da Cruz, Ivana; Daniel, Hannelore; Duster, Troy; Ebbesson, Sven; Elliott, Ruan; Fairweather-Tait, Susan; Felton, Jim; Fenech, Michael; Finley, John; Fogg Johnson, Nancy; Gill Garrison, Rosalynn; Gibney, Michael; Gillies, Peter; Gustavsson, Jan-Ake; Hartman, John; He, Lin; Hwang, Jae-Kwan; Jais, Jean-Philippe; Jang, Yangsoo; Joost, Hans; Junien, Claudine; Kanter, Mitchell; Kibbe, Warren; Koletzko, Berthold; Korf, Bruce; Kornman, Kenneth; Krempin, David; Langin, Dominique; Lauren, Denis; Ho Lee, Jong; Leveille, Gilbert; Lin, Su-Ju; Mathers, John; Mayne, Michael; McNab, Warren; Milner, John; Morgan, Peter; Muller, Michael; Nikolsky, Yuri; Van der Ouderaa, Frans; Park, Taesun; Pensel, Norma; Pérez Jiménez, Francisco; Poutanen, Kaisa; Roberts, Matthew; Saris, Wim; Schuster, Gertrud; Shelling, Andrew; Simopoulos, Artemis; Southon, Sue; Tai, Shyong; Towne, Bradford; Trayhurn, Paul; Uauy Dagach-Imbarack, Ricardo; Visek, Willard; Warden, Craig; Weiss, Rick; Wiencke, John; Winkler, Jack; Wolff, George; Zhao-Wilson, Xi; Zucker, Jean-Daniel (CABI PUBLISHING, 2005-11)
      Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into nutrients, antinutrients, ...
    • Suazo Romo, Miriam; Olivares, Felipe; Méndez, Marco; Pulgar Tejo, Rodrigo; Prohaska, Joseph R.; Arredondo Olguín, Miguel Armando; Pizarro Aguirre, Fernando; Ordóñez Pizarro, Fernando; Araya, Magdalena; González Canales, Mauricio (ELSEVIER SCIENCE INC, 2008-04)
      The limits of copper homeostatic regulation in humans are not known, making it difficult to define the milder effects of early copper excess. Furthermore, a robust assay to facilitate the detection of early stages of ...