Browsing by Author "Lavandero González, Sergio"

Now showing items 1-7 of 7

    • Atrial Function Assessed by Speckle Tracking Echocardiography Is a Good Predictor of Postoperative Atrial ... 
      Verdejo, Hugo E.; Becerra, Elia; Zalaquett Sepúlveda, Ricardo; Campo, Andrea del; García Nannig, Lorena; Troncoso Cotal, Rodrigo; Chiong Lay, Mario; Marín, Arnaldo; Castro, Pablo F.; Lavandero González, Sergio; Gabrielli, Luigi A.; Corbalán, Ramón (Wiley & Sons, 2016)
      ObjectiveAdvanced age is an independent predictor of postoperative atrial fibrillation (POAF) in patients undergoing coronary artery bypass surgery. We evaluated whether left atrial (LA) dysfunction assessed by strain ...
    • beta -Hydroxybutyrate increases exercise capacity associated with changes in mitochondrial function in ... 
      Monsalves Álvarez, Matías; Morales Campos, Pablo; Castro Sepúlveda, Mauricio; Sepúlveda Guzmán, Carlos; Rodríguez Silva, Juan Manuel; Chiong Lay, Mario; Eisner, Verónica; Lavandero González, Sergio; Troncoso Cotal, Rodrigo (MDPI, 2020)
      beta-hydroxybutyrate is the main ketone body generated by the liver under starvation. Under these conditions, it can sustain ATP levels by its oxidation in mitochondria. As mitochondria can modify its shape and function ...
    • Calcium sensing receptor as a novel mediator of adipose tissue dysfunction: mechanisms and potential clinical ... 
      Bravo Sagua, Roberto; Mattar, Pamela; Díaz, Ximena; Lavandero González, Sergio; Cifuentes, Mariana (Frontiers Media, 2016)
      Obesity is currently a serious worldwide public health problem, reaching pandemic levels. For decades, dietary and behavioral approaches have failed to prevent this disease from expanding, and health authorities are ...
    • Calcium-Sensing Receptor in Adipose Tissue: Possible Association with Obesity-Related Elevated Autophagy 
      Mattar, Pamela; Pino Sanhueza, Sofía Carolina; Yuri, Gabriela; Briones, Lautaro; Pérez Leighton, Claudio; Rudich, Assaf; Lavandero González, Sergio; Cifuentes Koster, Mariana (MDPI, 2020)
      Autophagy is upregulated in adipose tissue (AT) from people with obesity. We showed that activation of the calcium-sensing receptor (CaSR) elevates proinflammatory cytokines through autophagy in preadipocytes. Our aim is ...
    • Local Control of Nuclear Calcium Signaling in Cardiac Myocytes by Perinuclear Microdomains of Sarcolemmal ... 
      Ibarra, Cristián; Vicencio, José M.; Estrada Hormazábal, Manuel; Lin, Yingbo; Rocco, Paola; Rebellato, Paola; Muñoz, Juan P.; García Prieto, Jaime; Quest, Andrew F. G.; Chiong Lay, Mario; Davidson, Sean M.; Bulatovic, Ivana; Grinnemo, Karl Henrik; Larsson, Olle; Szabadkai, Gyorgy; Uhlén, Per; Jaimovich Pérez, Enrique; Lavandero González, Sergio (American Heart Association, 2013)
      Rationale: The ability of a cell to independently regulate nuclear and cytosolic Ca2+ signaling is currently attributed to the differential distribution of inositol 1,4,5-trisphosphate receptor channel isoforms in the ...
    • Mifepristone enhances insulin stimulated Akt phosphorylation and glucose uptake in skeletal muscle cells 
      Bernal Sore, Izela; Navarro Márquez, Mario F.; Osorio Fuentealba, César; Díaz Castro, Francisco; Campo, Andrea del; Donoso Barraza, Camila; Porras Espinoza, Omar; Lavandero González, Sergio; Troncoso Cotal, Rodrigo (Elsevier, 2018)
      Mifepristone is the only FDA-approved drug for glycaemia control in patients with Cushing's syndrome and type 2 diabetes. Mifepristone also has beneficial effects in animal models of diabetes and patients with antipsychotic ...
    • Science and health policies to tackle chronic diseases in Chile 
      Bambs, Claudia; Bravo Sagua, Roberto; Margozzini, Paula; Lavandero González, Sergio (Elsevier, 2020)
      Chile has experienced rapid epidemiological transitions characterized by decreasing infant mortality, population aging, and a shift towards obesity with an increase in noncommunicable diseases (NCDs). Today, tobacco, ...