Browsing by Author "Sierralta, Walter"

Now showing items 1-10 of 10

    • Administration of High Doses of Copper to Capuchin Monkeys Does Not Cause Liver Damage but Induces ... 
      Araya, Magdalena; Núñez, Héctor; Pavez, Leonardo; Arredondo Olguín, Miguel Armando; Méndez, Marco; Cisternas, Felipe; Pizarro Aguirre, Fernando; Sierralta, Walter; Uauy Dagach-Imbarack, Ricardo; González Canales, Mauricio (American Society for Nutrition, 2012)
      Liver cells respond to copper loading upregulating protective mechanisms. However, to date, except for liver content, there are no good indicators that identify individuals with excess liver copper. We hypothesized that ...
    • Adult hippocampus derived soluble factors induce a neuronal-like phenotype in mesenchymal stem cells 
      Rivera, Francisco J.; Sierralta, Walter; Minguell, José J.; Aigner, Ludwig (ELSEVIER, 2006-10-02)
      Bone marrow-derived mesenchymal stem cells (MSCs) are not restricted in their differentiation fate to cells of the mesenchymal lineage. They acquire a neural phenotype in vitro and in vivo after transplantation in the ...
    • A cyclic peptide derived from alpha-fetoprotein inhibits the proliferative effects of the epidermal growth ... 
      Torres, Crístian; Antileo, Elmer; Epuñán, María José; Pino, Ana María; Valladares Boasi, Luis; Sierralta, Walter (PROFESSOR D A SPANDIDOS, 2008-06)
      A cyclic peptide derived from the active domain of α-fetoprotein (AFP) significantly inhibited the proliferation of MCF7 cells stimulated with the epidermal growth factor (EGF) or estradiol (E2). The action of these ...
    • Effects of chronic copper exposure during early life in rhesus monkeys 
      Araya, Magdalena; Kelleher, Shannon; Arredondo Olguín, Miguel; Sierralta, Walter; Vial, María Teresa; Uauy Dagach-Imbarack, Ricardo; Lonnerdal, Bo (AMER SOC CLINICAL NUTRITION, 2005-05)
      Background: Whether infants regulate copper absorption and the potential effects of excess copper in early life remain poorly defined. Objective: The objective of the study was to assess copper retention, liver copper ...
    • Intracellular localization of Arabidopsis sulfurtransferases 
      Bauer, Michael; Dietrich, Christof; Nowak, Katharina; Sierralta, Walter; Papenbrock, Jutta (AMER SOC PLANT BIOLOGISTS, 2004-06)
      Sulfurtransferases (Str) comprise a group of enzymes widely distributed in archaea, eubacteria, and eukaryota which catalyze the transfer of a sulfur atom from suitable sulfur donors to nucleophilic sulfur acceptors. In ...
    • Melatonin administration impairs visuo-spatial performance and inhibits neocortical long-term potentiation in rats 
      Soto Moyano, Rubén; Burgos, Héctor; Flores, Francisco; Valladares Boasi, Luis; Sierralta, Walter; Fernández Hidalgo, Víctor; Pérez, Hernán; Hernández, Paula; Hernández, Alejandro (PERGAMON-ELSEVIER SCIENCE LTD, 2006-10)
      Melatonin has been shown to inhibit long-term potentiation (LTP) in hippocampal slices of rats. Since LTP may be one of the main mechanisms by which memory traces are encoded and stored in the central nervous system, it ...
    • Mild prenatal protein malnutrition increases alpha(2C)-adrenoceptor density in the cerebral cortex during ... 
      Soto Moyano, Rubén; Valladares Boasi, Luis; Sierralta, Walter; Pérez, Hernán; Mondaca, Mauricio; Fernández, Víctor; Burgos, Héctor; Hernández Hidalgo, Alejandro (BLACKWELL PUBLISHING LTD, 2005-06)
      Mild reduction in the protein content of the mother's diet from 25 to 8% casein, calorically compensated by carbohydrates, does not alter body and brain weights of rat pups at birth, but leads to significant enhancements ...
    • Mild prenatal protein malnutrition increases alpha(2C)-adrenoceptor expression in the rat cerebral cortex ... 
      Sierralta, Walter; Hernández, Alejandro; Valladares Boasi, Luis; Pérez, Hernán; Mondaca, Mauricio; Soto Moyano, Rubén (PERGAMON-ELSEVIER SCIENCE LTD, 2006-05-15)
      Mild reduction in the protein content in the diet of pregnant rats from 25 to 8% casein, calorically compensated by carbohydrates, does not alter body and brain weights of rat pups at birth, but results in significant ...
    • Ultrastructural and biochemical evidence for the presence of mature steroidogenic acute regulatory protein ... 
      Sierralta, Walter; Kohen Skop, Paulina; Castro, Olga; Muñoz Gallardo, Alex; Strauss III, Jerom F.; Devoto, Luigi (ELSEVIER IRELAND LTD, 2005-10-20)
      The distribution of the steroidogenic acute regulatory protein (StAR) inside thecal and granulosa-lutein cells of human corpus luteum 9 (CL) was assessed by immunoelectron microscopy. We found greater levels of StAR ...
    • Weight increase and overweight are associated with DNA oxidative damage in skeletal muscle 
      Maza Cave, María Pía de la; Olivares, Daniela; Hirsch Birn, Sandra; Sierralta, Walter; Gattas, Vivien; Barrera Acevedo, María; Bunout Barnett, Daniel; Leiva Balich, Laura; Fernández, Mireya (CHURCHILL LIVINGSTONE, 2006-12)
      Background and aims: Weight maintenance within normal standards is recommended for prevention of conditions associated with oxidative injury. To compare oxidative damage in a post mitotic tissue, between adults differing ...