Browsing by Author "Smith, Patricio C."
Now showing items 1-6 of 6
-
Cáceres, Mónica; Tobar, Nicolás; Guerrero, Javier; Smith, Patricio C.; Martínez, Jorge (WILEY-LISS, DIV JOHN WILEY & SONS INC, 2008-02-15)In this study, we demonstrated that tyrosine phosphorylation of EGFR and the autocrine expression of uPA and HB-EGF depend on the activity of c-jun amino-terminal kinase (JNK) in human prostatic DU-145 cells. These cells ...
-
Retamal, Ignacio N.; Hernández, Romina; Melo, Francisco; Zapata, Paulina; Martínez Winkler, Jorge; Martínez, Constanza; Smith, Patricio C. (American Academy of Periodontology, 2017)Background: Glucose-derived metabolites may alter the structure and biologic properties of important proteins in periodontium, such as collagens. As a consequence, it is possible that collagen-binding cells may change their ...
-
Tobar, Nicolás; Guerrero, Javier; Smith, Patricio C.; Martínez, Jorge (NATURE PUBLISHING GROUP, 2010-09-28)BACKGROUND: The influence of the stromal microenvironment on the progression of epithelial cancers has been demonstrated. Unravelling the mechanisms by which stromal cells affect epithelial behaviour will contribute in ...
-
Tobar, Nicolás; Cáceres, Mónica; Santibáñez, Juan Francisco; Smith, Patricio C.; Martínez, Jorge (Elsevier Inc., 2008-08-18)modulate the migratory properties in MCF-7 and T47D human mammary cell lines. We also described that the NFjB pathway exerts a downstream control on the expression of the ROS-dependent cellular migratory potential. These ...
-
Guerrero, Javier; Tobar, Nicolás; Cáceres, Mónica; Espinoza, Lorena; Escobar, Paula; Dotor, Javier; Smith, Patricio C.; Martínez, Jorge (Springer, 2010)In carcinomas such as those of breast, pancreas, stomach, and colon, cancer cells support the expansion of molecular and cellular stroma in a phenomenon termed desmoplasia, which is characterized by a strong fibrotic response. ...
-
Guerrero, Javier; Tobar, Nicolás; Cáceres, Mónica; Espinoza, Lorena; Escobar Oliva, Paula; Dotor, Javier; Smith, Patricio C.; Martínez Winkler, Jorge (Springer Science+Business Media, 2011)In carcinomas such as those of breast, pancreas, stomach, and colon, cancer cells support the expansion of molecular and cellular stroma in a phenomenon termed desmoplasia, which is characterized by a strong fibrotic response. ...