Now showing items 1-9 of 9

    • Olivares Grohnert, Manuel; Figueroa Donoso, Constanza; Pizarro Aguirre, Fernando (Humana Press, 2016)
      The objective of the study is to determine the effect of copper (Cu) plus the reducing agent ascorbic acid (AA) on the absorption of non-heme iron (Fe). Experimental study with block design in which each subject was his ...
    • Candia, Valeria; Ríos Castillo, Israel; Carrera Gil, Frank; Vizcarra, Berta; Olivares, Manuel; Chaniotakis, Sotiris; Pizarro Aguirre, Fernando (Elsevier, 2018)
      Introduction: Micronutrient deficiencies are one of the most important public health issues worldwide and iron (Fe) deficiency anemia is the most prevalent micronutrient deficiency. Iron deficiency often coexists with ...
    • Espinoza, A.; Morales, S.; Arredondo Olguín, Miguel (Springer, 2014)
      Epidemiological studies have reported an association between high iron (Fe) levels and elevated risk of developing type 2 diabetes mellitus (T2D). It is believed that the formation of Fe-catalyzed hydroxyl radicals may ...
    • Fuentes, Marcela; Andrews, Mónica; Arredondo Olguín, Miguel Armando (Springer Science+Business Media, 2013)
      Type 2 diabetes is characterized by hyperglycemia and oxidative stress. Hyperglycemia is linked to mitochondrial dysfunction and reduced β-cell mass due to the reduced expression of genes such as Mfn2 as well as ...
    • Middleton Santibáñez, Maureen; Olivares Grohnert, Manuel Alonso; Espinoza, Alejandra; Arredondo Olguín, Miguel Armando; Pizarro Aguirre, Fernando Dagoberto; Valenzuela Venegas, Carolina Paz (MDPI, 2021)
      Currently, all pigs raised on intensive farms develop iron-deficiency anemia if they do not receive supplemental iron at birth. Weaning diets commonly contain high concentrations of iron, and the effect on the copper and ...
    • Mendiburo, María José; Flores, Sebastián; Pizarro Aguirre, Fernando; Arredondo Olguín, Miguel Armando (2006)
      Heme oxygenase-1 is a microsomal enzyme that, when induced by stress, protects the cells from oxidative injury. Heme oxygenase-1 participates in the cleavage of the heme ring producing biliverdin, CO and ferrous Fe. The ...
    • Leiva, Elba; Mujica, Verónica; Sepúlveda, Pablo; Guzmán, Luis; Núñez, Sergio; Orrego, Roxana; Palomo, Iván; Andrews, Mónica; Arredondo Olguín, Miguel Armando (Springer, 2013)
      Studies concerning oxidative stress (OxE) parameters have increased, mainly because of its important role in cardiovascular diseases and diabetes complications. The main objective of this study was to evaluate iron ...
    • Ríos Castillo, Israel; Olivares Grohnert, Manuel; Brito, Álex; López de Romaña, Daniel; Pizarro Aguirre, Fernando (Elsevier, 2014)
      Objectives: Calcium (Ca) and iron (Fe) are essential minerals for normal growth and development. Although previous studies have shown that Ca inhibits acute Fe absorption, there is no evidence of the possible long- or ...
    • Mujica Coopman, María; Brito, Alex; López de Romaña, Daniel; Ríos Castillo, Israel; Cori, Héctor; Olivares, Manuel (SAGE, 2015)
      Background: In Latin America and the Caribbean, anemia has been a public health problem that affects mainly women of childbearing age and children under 6 years of age. However, the current prevalence of anemia in this ...