Browsing by Subject "Mitochondria"

Now showing items 1-4 of 4

    • In vitro study of the protective effect of manganese against vanadium mediated nuclear and mitochondrial DNA damage 
      Rivas García, Lorenzo; Quiles, José L.; Varela López, Alfonso; Arredondo Olguín, Miguel; López, Paulina; Rodríguez Diéguez, Antonio; Montes Bayón, María; Aranda, Pilar; Llopis, Juan; Sánchez González, Cristina (Elsevier, 2020)
      We aimed to study the effect of vanadium(V) exposure on cell viability, nuclear DNA (nDNA) and mitochondrial DNA (mtDNA) and to elucidate if these effects can be reverted by co-exposure to V and manganese (Mn). HepG2 cells ...
    • Mifepristone enhances insulin stimulated Akt phosphorylation and glucose uptake in skeletal muscle cells 
      Bernal Sore, Izela; Navarro Márquez, Mario F.; Osorio Fuentealba, César; Díaz Castro, Francisco; Campo, Andrea del; Donoso Barraza, Camila; Porras Espinoza, Omar; Lavandero González, Sergio; Troncoso Cotal, Rodrigo (Elsevier, 2018)
      Mifepristone is the only FDA-approved drug for glycaemia control in patients with Cushing's syndrome and type 2 diabetes. Mifepristone also has beneficial effects in animal models of diabetes and patients with antipsychotic ...
    • Mifepristone for treatment of metabolic syndrome: beyond cushing’s syndrome 
      Díaz Castro, Francisco; Monsalves Álvarez, Matías; Rojo, Leonel E.; Campo, Andrea del; Troncoso, Rodrigo (Frontiers Media, 2020)
      A growing body of research indicates that cortisol, the glucocorticoid product of the activation of the hypothalamic-pituitary-adrenal axis, plays a role in the pathophysiology of metabolic syndrome. In this regard, chronic ...
    • Sucralose stimulates mitochondrial bioenergetics in Caco-2 Cells 
      Bórquez, Juan Carlos; Hidalgo, Miltha; Rodríguez, Juan M.; Montaña, Alejandra; Porras Espinoza, Omar Hugo; Troncoso Cotal, Rodrigo Hernan; Bravo Sagua, Roberto Francisco (Frontiers Media, 2021)
      Sucralose is a non-caloric artificial sweetener widely used in processed foods that reportedly affects energy homeostasis through partially understood mechanisms. Mitochondria are organelles fundamental for cellular ...