Synthesis of conformationally restricted N-{4-[4-(4,7-Dimethoxy-Benzo[b]Thiophene-2-Carbonyl)-1-Piperazinyl]-Phenyl}-Arylcarboxamides potential ligands with 5-HT1A binding affinity

Author	dc.contributor.author	Pessoa Mahana, Hernán	es_CL
Author	dc.contributor.author	González Lira, Christian Guillermo	es_CL
Author	dc.contributor.author	Araya Maturana, Ramiro	es_CL
Author	dc.contributor.author	Saitz Barría, Claudio
Author	dc.contributor.author	Pessoa, D.	es_CL
Admission date	dc.date.accessioned	2009-08-25T16:58:24Z
Available date	dc.date.available	2009-08-25T16:58:24Z
Publication date	dc.date.issued	2009-06
Cita de ítem	dc.identifier.citation	JOURNAL OF THE CHILEAN CHEMICAL SOCIETY 54(2): 147-150	en
Identifier	dc.identifier.issn	0717-9324
Identifier	dc.identifier.uri	https://repositorio.uchile.cl/handle/2250/120779
Abstract	dc.description.abstract	New benzothiophene arylpiperazine derivatives 7 (a-1) were synthesized as potential serotoninergic agents with 5-HT1A receptor affinity. Preparation of the derivatives was performed by reaction of 1-(4-aminophenyl)-4-[(4,7-dimethoxy-1-benzothien-2-yl)carbonyl] piperazine (6) with a series of substituted aroyl chlorides.	en
Lenguage	dc.language.iso	en	en
Publisher	dc.publisher	SOC CHILENA QUIMICA	en
Keywords	dc.subject	Secotonine	en
Título	dc.title	Synthesis of conformationally restricted N-{4-[4-(4,7-Dimethoxy-Benzo[b]Thiophene-2-Carbonyl)-1-Piperazinyl]-Phenyl}-Arylcarboxamides potential ligands with 5-HT1A binding affinity	en
Document type	dc.type	Artículo de revista