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Síndrome metabólico en niños y adolescentes: asociación con sensibilidad insulínica y con magnitud y distribución de la obesidad

Authordc.contributor.authorBurrows, Raquel es_CL
Authordc.contributor.authorLeiva, Laura es_CL
Authordc.contributor.authorWeisstaub Nuta, Sergio es_CL
Authordc.contributor.authorCeballos, Ximena es_CL
Authordc.contributor.authorGattas, Vivien es_CL
Authordc.contributor.authorLera Marques, Lydia es_CL
Authordc.contributor.authorAlbala Brevis, Cecilia es_CL
Admission datedc.date.accessioned2008-05-08T11:44:52Z
Available datedc.date.available2008-05-08T11:44:52Z
Publication datedc.date.issued2007es_CL
Cita de ítemdc.identifier.citationREVISTA MEDICA DE CHILE Vol. 135 FEB 2007 2 174-181es_CL
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/123831
General notedc.descriptionPublicación ISIes_CL
Abstractdc.description.abstractBackground In Chile between 1986 and 1998, the prevalence of obesity has increased from 4.696 to 24% in prepuberal and from 2.3% to 17% in puberal children. Aim To assess the prevalence of metabolic syndrome (MS) in a sample of obese and overweight Chilean children. Patients and methods: Descriptive study in 489 children (273 females), aged from 6 to 16 years consulting in an obesity program. Body mass index, Tanner puberal development, waist circumference, blood pressure fasting blood glucose, insulin and lipid levels were measured. Insulin sensitivity was calculated using the mathematical models QUICKI and HOMA. MS was diagnosed when three or snore of the following criteria were met a waist circumference over percentile 90, a blood pressure over percentile 90, serum triglycerides over 110 mg/dl, HDL cholesterol of less than 40 mg/dl or a fasting blood glucose level over 100 mg/dl. Results: MS was present in 4% of children with overweight and 30% of obese children. No differences in prevalence were observed for sex or puberal development. The most prevalent cardiovascular risk factors were abdominal obesity, present in 76% of the sample and high trzclycerzdes levels in 39%. The less prevalent risk factor was a fasting blood glucose over 100 mg/dl in 3.7%. The risk for MS increased ten fold in children with severe obesity, compared with those with overweight Those with abdominal obesity bad a 17 times higher risk of MS. Basal insulin sensitivity was significantly associated with the number of cardiovascular risk factors and the presence of MS. Conclusions: In this sample of children, fat distribution and the severity of obesity were strong determinants of MS. Waist circumference had a higher impact on MS than body mass indexes_CL
Lenguagedc.language.isoenes_CL
Keywordsdc.subjectinfant overnutritiones_CL
Area Temáticadc.subject.otherMedicine, General & Internales_CL
Títulodc.titleSíndrome metabólico en niños y adolescentes: asociación con sensibilidad insulínica y con magnitud y distribución de la obesidad
Title in another languagedc.title.alternativePrevalence of metabolic syndrome in a sample of Chilean children consulting in an obesity clinic
Document typedc.typeArtículo de revistaes_CL


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