Author | dc.contributor.author | Birch, Eileen E. | es_CL |
Author | dc.contributor.author | Garfield, Sharon | es_CL |
Author | dc.contributor.author | Castañeda, Yolanda | es_CL |
Author | dc.contributor.author | Hughbanks Wheaton, Dianna | es_CL |
Author | dc.contributor.author | Uauy Dagach-Imbarack, Ricardo | es_CL |
Author | dc.contributor.author | Hoffman, Dennis | es_CL |
Admission date | dc.date.accessioned | 2008-05-08T11:56:30Z | |
Available date | dc.date.available | 2008-05-08T11:56:30Z | |
Publication date | dc.date.issued | 2007 | es_CL |
Cita de ítem | dc.identifier.citation | EARLY HUMAN DEVELOPMENT Vol. 83 MAY 2007 5 279-284 | es_CL |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/123832 | |
General note | dc.description | Publicación ISI | es_CL |
Abstract | dc.description.abstract | Background: While there is a large body of data on the effects of long-chain polyunsaturated fatty acid supplementation of infant formula on visual and cognitive maturation during infancy, longterm visual and cognitive outcome data from randomized trials are scarce. Aim: To evaluate docosahexaenoic acid (DHA) and arachidonic acid (ARA)-supplementation of infant formula on visual and cognitive outcomes at 4 years of age. Methods: Fifty-two of 79 healthy term infants who were enrolled in a single-center, double-blind, randomized clinical trial of DHA and ARA supplementation of infant formula were available for follow-up at 4 years of age. In addition, 32 breast-fed infants served as a "gold standard". Outcome measures were visual acuity and the Wechsler Preschool and Primary Scale of Intelligence - Revised. Results: At 4 years, the control formula group had poorer visual acuity than the breast-fed group; the DHA- and DHA+ARA-supplemented groups did not differ significantly from the breast-fed group. The control formula and DHA-supplemented groups had Verbal IQ scores poorer than the breast-fed group. Conclusion: DHA and ARA-supplementation of infant formula supports visual acuity and IQ maturation similar to that of breast-fed infants. (C) 2006 Elsevier Ireland Ltd. All rights reserved. | es_CL |
Lenguage | dc.language.iso | en | es_CL |
Keywords | dc.subject | long-chain polyunsaturated | es_CL |
Area Temática | dc.subject.other | Obstetrics & Gynecology; Pediatrics | es_CL |
Título | dc.title | Visual acuity and cognitive outcomes at 4 years of age in a double-blind, randomized trial of long-chain polyunsaturated fatty acid-supplemented infant formula | es_CL |
Document type | dc.type | Artículo de revista | |