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High cardiometabolic risk in healthy Chilean adolescents: associations with anthropometric, biological and lifestyle factors

Authordc.contributor.authorBurrows, Raquel 
Authordc.contributor.authorCorrea Burrows, Paulina 
Authordc.contributor.authorReyes Jedlicki, Marcela 
Authordc.contributor.authorBlanco, Estela 
Authordc.contributor.authorAlbala Brevis, Cecilia 
Authordc.contributor.authorGahagan, Sheila 
Admission datedc.date.accessioned2016-06-29T21:34:25Z
Available datedc.date.available2016-06-29T21:34:25Z
Publication datedc.date.issued2016
Cita de ítemdc.identifier.citationPublic Health Nutrition: 19(3), 486–493 (2016)en_US
Identifierdc.identifier.otherDOI: 10.1017/S136898001500158
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/139274
General notedc.descriptionArtículo de publicación ISIen_US
Abstractdc.description.abstractObjective: To analyse the prevalence of cardiovascular risk factors in healthy adolescents of low to middle socio-economic status and to study the influence of anthropometric, biological and lifestyle factors on the risk of metabolic syndrome (MetS). Design: Cross-sectional study. BMI, waist circumference, blood pressure, fat and lean mass (by dual-energy X-ray absorptiometry), TAG, HDL-cholesterol, glucose, insulin, homeostatic model assessment-insulin resistance index (HOMA-IR), food intake and physical activity were measured. Cardiovascular risk factors were defined using the International Diabetes Federation criteria and insulin resistance using HOMA-IR >= 2.6. Bivariate and multivariate regressions examined the associations between MetS and anthropometric, biological and lifestyle factors. Setting: Observational cohort study including Chilean adolescents, who were part of a follow-up study beginning in infancy. Subjects: Adolescents aged 16-17 years (n 667). Results: In the sample, 16.2 % had obesity and 9.5 % had MetS. Low HDL-cholesterol (69.9 %), abdominal obesity (33.3 %) and fasting hyperglycaemia (8.7 %) were the most prevalent cardiovascular risk factors. In males, obesity (OR = 3.7; 95 % CI 1.2, 10.8), insulin resistance (OR = 3.0; 95 % CI 1.1, 8.2), physical inactivity (OR = 2.9; 95 % CI 1.1, 7.7) and sarcopenia (OR = 21.2; 95 % CI 4.2, 107.5) significantly increased the risk of MetS. In females, insulin resistance (OR = 4.9; 95 % CI 1.9, 12.6) and sarcopenia (OR = 3.6; 95 % CI 1.1, 11.9) were significantly associated with MetS. Conclusions: High prevalences of obesity, abdominal obesity, dyslipidaemia, fasting hyperglycaemia and MetS were found in healthy adolescents. In both sexes, sarcopenia and insulin resistance were important risk factors of MetS. Promotion of active lifestyles at the school level and regulation of the sale of energy-dense foods are needed.en_US
Patrocinadordc.description.sponsorshipNational Heart, Lung, and Blood Institute, National Institutes of Health R01HL088530-2980925; Advanced Human Capital Program from National Council for Scientific Research and Technology (CONICYT) (Chile) 79140003en_US
Lenguagedc.language.isoenen_US
Publisherdc.publisherCAMBRIDGE UNIV PRESSen_US
Type of licensedc.rightsAtribución-NoComercial-SinDerivadas 3.0 Chile*
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/*
Keywordsdc.subjectMetabolic syndromeen_US
Keywordsdc.subjectCardiovascular and metabolic risken_US
Keywordsdc.subjectAdolescentsen_US
Keywordsdc.subjectObesityen_US
Keywordsdc.subjectSarcopeniaen_US
Keywordsdc.subjectInsulin resistanceen_US
Títulodc.titleHigh cardiometabolic risk in healthy Chilean adolescents: associations with anthropometric, biological and lifestyle factorsen_US
Document typedc.typeArtículo de revistaen_US


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Atribución-NoComercial-SinDerivadas 3.0 Chile
Except where otherwise noted, this item's license is described as Atribución-NoComercial-SinDerivadas 3.0 Chile