Gastroprotective activity of epitaondiol and sargaol
| Author | dc.contributor.author | Areche, Carlos | |
| Author | dc.contributor.author | San Martín Barrientos, Aurelio | |
| Author | dc.contributor.author | Rovirosa, Juana | |
| Author | dc.contributor.author | Sepúlveda, Beatriz | |
| Admission date | dc.date.accessioned | 2018-12-20T14:06:15Z | |
| Available date | dc.date.available | 2018-12-20T14:06:15Z | |
| Publication date | dc.date.issued | 2011 | |
| Cita de ítem | dc.identifier.citation | Natural Product Communications, Volumen 6, Issue 8, 2018, Pages 1073-1074 | |
| Identifier | dc.identifier.issn | 1934578X | |
| Identifier | dc.identifier.issn | 15559475 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/153875 | |
| Abstract | dc.description.abstract | The effects of epitaondiol (1) and sargaol (2), isolated from the brown alga Stypopodium flabelliforme on HCl/ethanol-induced gastric lesions in mice were evaluated and compared with that of lansoprazole. Epitaondiol and sargaol (6.25- 50 mg/kg) dose-dependently inhibited the appearance of gastric lesions in mice, displaying similar values to lansoprazole at 20 mg/kg. Both epitaondiol and sargaol showed gastroprotective activity with ED 50 values of 40 mg/kg and 35 mg/kg, respectively. The results suggest that epitaondiol and sargaol protect the gastric mucosa in the HCl/EtOH model in mice. | |
| Lenguage | dc.language.iso | en | |
| Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
| Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
| Source | dc.source | Natural Product Communications | |
| Keywords | dc.subject | Epitaondiol | |
| Keywords | dc.subject | Gastroprotective activity | |
| Keywords | dc.subject | Sargaol | |
| Keywords | dc.subject | Stypopodium flabelliforme | |
| Título | dc.title | Gastroprotective activity of epitaondiol and sargaol | |
| Document type | dc.type | Artículo de revista | |
| Cataloguer | uchile.catalogador | SCOPUS | |
| Indexation | uchile.index | Artículo de publicación SCOPUS | |
| uchile.cosecha | uchile.cosecha | SI |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile