Medicinal plants of Chile: Evaluation of their anti-trypanosoma cruzi activity
| Author | dc.contributor.author | Muñoz, Orlando M. | |
| Author | dc.contributor.author | Maya Arango, Juan | |
| Author | dc.contributor.author | Ferreira, Jorge | |
| Author | dc.contributor.author | Christen, Philippe | |
| Author | dc.contributor.author | San Martín, José | |
| Author | dc.contributor.author | López Muñoz, Rodrigo | |
| Author | dc.contributor.author | Morello Casté, Antonio | |
| Author | dc.contributor.author | Kemmerling Weis, Ulrike | |
| Admission date | dc.date.accessioned | 2018-12-20T14:13:58Z | |
| Available date | dc.date.available | 2018-12-20T14:13:58Z | |
| Publication date | dc.date.issued | 2013 | |
| Cita de ítem | dc.identifier.citation | Zeitschrift fur Naturforschung - Section C Journal of Biosciences, Volumen 68 C, Issue 5-6, 2018, Pages 198-202 | |
| Identifier | dc.identifier.issn | 09395075 | |
| Identifier | dc.identifier.other | 10.1515/znc-2013-5-605 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/155042 | |
| Abstract | dc.description.abstract | The extracts of several plants of Central Chile exhibited anti-Trypanosoma cruzi trypomastigotes activity. Most active extracts were those obtained from Podanthus ovatifolius, Berberis microphylla, Kageneckia oblonga, and Drimys winteri. The active extract of Drimys winteri (IC50 51.2 μg/mL) was purified and three drimane sesquiterpenes were obtained: polygodial, drimenol, and isodrimenin. Isodrimenin and drimenol were found to be active against the trypomastigote form of T. cruzi with IC50 values of 27.9 and 25.1 μM, respectively. © 2013 Verlag der Zeitschrift für Naturforschung, Tübingen. | |
| Lenguage | dc.language.iso | en | |
| Publisher | dc.publisher | Verlag der Zeitschrift fur Naturforschung | |
| Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
| Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
| Source | dc.source | Zeitschrift fur Naturforschung - Section C Journal of Biosciences | |
| Keywords | dc.subject | Anti-Trypanosoma cruzi | |
| Keywords | dc.subject | Drimenol | |
| Keywords | dc.subject | Isodrimeni | |
| Título | dc.title | Medicinal plants of Chile: Evaluation of their anti-trypanosoma cruzi activity | |
| Document type | dc.type | Artículo de revista | |
| dcterms.accessRights | dcterms.accessRights | Acceso Abierto | |
| Cataloguer | uchile.catalogador | SCOPUS | |
| Indexation | uchile.index | Artículo de publicación SCOPUS | |
| uchile.cosecha | uchile.cosecha | SI |
Files in this item
This item appears in the following Collection(s)
-
Artículos de revistas
Artículos de revistas
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile