Microsomal and peroxisomal fatty acid oxidation in streptozotocin diabetic rat liver
| Author | dc.contributor.author | Orellana, Myriam | |
| Author | dc.contributor.author | Valdés, Elena | |
| Author | dc.contributor.author | Del Villar, Eugenia | |
| Admission date | dc.date.accessioned | 2018-12-20T14:32:18Z | |
| Available date | dc.date.available | 2018-12-20T14:32:18Z | |
| Publication date | dc.date.issued | 1997 | |
| Cita de ítem | dc.identifier.citation | General Pharmacology, Volumen 28, Issue 3, 2018, Pages 361-364 | |
| Identifier | dc.identifier.issn | 03063623 | |
| Identifier | dc.identifier.other | 10.1016/S0306-3623(96)00231-5 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/156340 | |
| Abstract | dc.description.abstract | Microsomal lauric acid hydroxylation and fatty acid peroxisomal β-oxidation were studied in hepatic subcellulant preparations from streptozotocin-induced diabetic and diabetic insulin-treated rats. The liver microsomes of the streptozotocin diabetic rats displayed a similar activity to hydroxylate lauric acid as the control microsomes. Diabetic insulin-treated rats showed lower (ω1) and ω-lauric acid hydroxylase activities than diabetic and control rats. Streptozotocin-induced diabetes and diabetic insulin-treated rats exhibited no significant changes on peroxisomal palmitoyl CoA β-oxidation compared to the control rats. Both microsomal and peroxisomal fatty acid oxidation responded in a similar way in this model of experimental diabetes. | |
| Lenguage | dc.language.iso | en | |
| Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
| Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
| Source | dc.source | General Pharmacology | |
| Keywords | dc.subject | lauric acid | |
| Keywords | dc.subject | liver cytochrome P-450 | |
| Keywords | dc.subject | peroxisomal fatty acid β-oxidation | |
| Keywords | dc.subject | streptozotocin-diabetic | |
| Título | dc.title | Microsomal and peroxisomal fatty acid oxidation in streptozotocin diabetic rat liver | |
| Document type | dc.type | Artículo de revista | |
| Cataloguer | uchile.catalogador | SCOPUS | |
| Indexation | uchile.index | Artículo de publicación SCOPUS | |
| uchile.cosecha | uchile.cosecha | SI |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile