Increased expression of c-rel, from the NF-κB/Rel family, in T cells from patients with systemic lupus erythematosus
Author
dc.contributor.author
Burgos, Patricia
Author
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Metz, Claudia
Author
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Bull, Paulina
Author
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Pincheira, Roxana
Author
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Massardo, Loreto
Author
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Errázuriz, Carolina
Author
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Bono Merino, María Rosa
Author
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Jacobelli, Sergio
Author
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González, Alfonso
Admission date
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2018-12-20T14:41:28Z
Available date
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2018-12-20T14:41:28Z
Publication date
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2000
Cita de ítem
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Journal of Rheumatology, Volumen 27, Issue 1, 2018, Pages 116-127
Identifier
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0315162X
Identifier
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https://repositorio.uchile.cl/handle/2250/157107
Abstract
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OBJECTIVE:
To explore the role of the NF
-
kappaB/Rel transcription factor family in autoimmunity,
we investigated whet
her peripheral blood mononuclear cells (PBMC) and T cells
from the blood of patients with systemic lupus erythematosus (SLE) exhibit abnormal
expression of c
-
rel, both when recently isolated and/or during in vitro activation.