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Sensitized photooxidation of thyroidal hormones. Evidence for heavy atom effect on singlet molecular oxygen [O2(1Δ g)]-mediated photoreactions

Authordc.contributor.authorMiskoski, Sandra 
Authordc.contributor.authorSoltermann, Arnaldo T. 
Authordc.contributor.authorMolina, Patricia G. 
Authordc.contributor.authorGünther Sapunar, Germán 
Authordc.contributor.authorZanocco Loyola, Antonio 
Authordc.contributor.authorGarcía, Norman A. 
Admission datedc.date.accessioned2018-12-20T15:04:11Z
Available datedc.date.available2018-12-20T15:04:11Z
Publication datedc.date.issued2005
Cita de ítemdc.identifier.citationPhotochemistry and Photobiology, Volumen 81, Issue 2, 2018, Pages 325-332
Identifierdc.identifier.issn00318655
Identifierdc.identifier.other10.1562/2004-10-27-RA-352.1
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/157482
Abstractdc.description.abstractThyronine derivatives are essential indicators of thyroid gland diseases in clinical diagnosis and are currently used as standards for developing ordinary biochemical assays. Photo-oxidation of gland hormones of the thyronine (TN) family and structurally related compounds (TN, 3,5-dliodothyronine,3,3′,5- triiodothyronine and 3,3′,5,5′-tetraiodothyronine or thyroxine) was studied using rose bengal, eosin and perinaphthenone (PN) as dye sensitizers. Tyrosine (Tyr) and two iodinated derivatives (3-iodotyrosine and 3,5-diiodotyrosine) were also included in the study for comparative purposes. Irradiation of aqueous solutions of substrates containing xanthene dyes with visible light triggers a complex series of competitive interactions, which include the triplet excited state of the dye (3Xdye*) and singlet molecular oxygen [O2(1Δg,)]- mediated and superoxide ion-mediated reactions. Rate constants for interaction with the 3Xdye*, attributed to an electron transfer process, are in the order o
Lenguagedc.language.isoen
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourcePhotochemistry and Photobiology
Keywordsdc.subjectBiochemistry
Keywordsdc.subjectPhysical and Theoretical Chemistry
Títulodc.titleSensitized photooxidation of thyroidal hormones. Evidence for heavy atom effect on singlet molecular oxygen [O2(1Δ g)]-mediated photoreactions
Document typedc.typeArtículo de revista
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile