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Author | dc.contributor.author | Squella Serrano, Juan | |
Author | dc.contributor.author | Zanocco, A. | |
Author | dc.contributor.author | Perna, S. | |
Author | dc.contributor.author | Núñez Vergara, Luis | |
Admission date | dc.date.accessioned | 2018-12-20T15:05:12Z | |
Available date | dc.date.available | 2018-12-20T15:05:12Z | |
Publication date | dc.date.issued | 1990 | |
Cita de ítem | dc.identifier.citation | Journal of Pharmaceutical and Biomedical Analysis, Volumen 8, Issue 1, 2018, Pages 43-47 | |
Identifier | dc.identifier.issn | 07317085 | |
Identifier | dc.identifier.other | 10.1016/0731-7085(90)80005-A | |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/157721 | |
Abstract | dc.description.abstract | Nitrendipine produces a well-defined polarographic peak due to the four-electron reduction of the nitro group. This peak is used for tracking the photodecomposition of nitrendipine in both UV light and daylight conditions. The results show that nitrendipine remains unaltered in the short time scale of a normal analytical procedure and no special care with visible light exposure is necessary. However nitrendipine is strongly altered with UV irradiation showing a first-order degradation kinetics. A degradation rate constant of 0.0665 min-1 with a t 1 2, of 10.423 min has been obtained. The UV degradation product was isolated and identified as the nitro pyridine analogue of nitrendipine. © 1990. | |
Lenguage | dc.language.iso | en | |
Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
Source | dc.source | Journal of Pharmaceutical and Biomedical Analysis | |
Keywords | dc.subject | Differential pulse polarography | |
Keywords | dc.subject | nitrendipine photodegradation. | |
Título | dc.title | A polarographic study of the photodegradation of nitrendipine | |
Document type | dc.type | Artículo de revista | |
Cataloguer | uchile.catalogador | SCOPUS | |
Indexation | uchile.index | Artículo de publicación SCOPUS | |
uchile.cosecha | uchile.cosecha | SI | |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile