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Authordc.contributor.authorSquella Serrano, Juan 
Authordc.contributor.authorNúñez Vergara, Luis 
Admission datedc.date.accessioned2018-12-20T15:05:13Z
Available datedc.date.available2018-12-20T15:05:13Z
Publication datedc.date.issued1990
Cita de ítemdc.identifier.citationBioelectrochemistry and Bioenergetics, Volumen 23, Issue 2, 2018, Pages 161-166
Identifierdc.identifier.issn03024598
Identifierdc.identifier.other10.1016/0302-4598(90)85005-3
Identifierdc.identifier.urihttps://repositorio.uchile.cl/handle/2250/157724
Abstractdc.description.abstractThe exposure of drugs to light produces photodecomposition processes in several cases: the drugs undergo important chemical changes with a parallel change in their activities or potencies and generally with a loss of their therapeutical actions. Generally, the chemical change in the molecule involves the reduction or oxidation of one photoactive group, producing a change in the redox behaviour of the molecule. Therefore electrochemical techniques can play an important role in the determination of light degradative processes in drugs. Specifically, in this work, we apply the polarographic technique to a study of the photodegradation process of some calcium antagonists of the dihydropyridine family. The degradation kinetics due to three light exposure conditions are reported. © 1990.
Lenguagedc.language.isoen
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourceBioelectrochemistry and Bioenergetics
Keywordsdc.subjectBiochemistry
Títulodc.titlePolarography as a technique for determining photodegradation in calcium antagonists
Document typedc.typeArtículo de revista
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile