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Gold nanoparticle-membrane interactions: Implications in biomedicine

Authordc.contributor.authorRiveros, Ana 
Authordc.contributor.authorDadlani, Komal 
Authordc.contributor.authorSalas, Edison 
Authordc.contributor.authorCaballero, Leonardo 
Authordc.contributor.authorMelo, Francisco 
Authordc.contributor.authorKogan Bocian, Marcelo 
Admission datedc.date.accessioned2018-12-20T15:10:55Z
Available datedc.date.available2018-12-20T15:10:55Z
Publication datedc.date.issued2013
Cita de ítemdc.identifier.citationJournal of Biomaterials and Tissue Engineering, Volumen 3, Issue 1, 2018, Pages 4-21
Identifierdc.identifier.issn21579091
Identifierdc.identifier.issn21579083
Identifierdc.identifier.other10.1166/jbt.2013.1067
Identifierdc.identifier.urihttp://repositorio.uchile.cl/handle/2250/158306
Abstractdc.description.abstractThere has been an increase in the research towards the use of nanoparticles as a promising tool for nanomedicine, from imagenology, drug and gene delivery, to phototherapy. Little is known regarding the interaction between nanoparticles and cell membranes despite its importance to achieve an efficient therapy avoiding adverse effects, such as cytotoxicity and accumulation in undesired targets. Gold nanoparticles have demonstrated to be a perfect candidate to use in biological systems because of their dimension, ease of characterization, biocompatibility, and ability to conjugate to different compounds, such as active peptides. There are different biophysical properties such as: shape, size, conjugation, surface charge and ligand arrangement that affect gold nanoparticlemembrane interactions. In this review we will analyze how these properties are involved in the mechanisms of interaction with membranes and the internalization pathways of gold nanoparticle systems into cells. A new appr
Lenguagedc.language.isoen
Publisherdc.publisherAmerican Scientific Publishers
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/cl/
Sourcedc.sourceJournal of Biomaterials and Tissue Engineering
Keywordsdc.subjectCell membrane
Keywordsdc.subjectDrug delivery
Keywordsdc.subjectGold nanoparticles
Keywordsdc.subjectLipid membrane model
Keywordsdc.subjectNanotoxicology
Títulodc.titleGold nanoparticle-membrane interactions: Implications in biomedicine
Document typedc.typeArtículo de revista
Catalogueruchile.catalogadorSCOPUS
Indexationuchile.indexArtículo de publicación SCOPUS
uchile.cosechauchile.cosechaSI


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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile