Sociodemographic predictors of early postnatal growth: evidence from a Chilean infancy cohort
Author
dc.contributor.author
Von Holle, Ann
Author
dc.contributor.author
North, Kari E.
Author
dc.contributor.author
Gahagan, Sheila
Author
dc.contributor.author
Burrows Argote, Raquel
Author
dc.contributor.author
Blanco, Estela
Author
dc.contributor.author
Lozoff, Betsy
Author
dc.contributor.author
Howard, Annie Green
Author
dc.contributor.author
Justice, Anne
Author
dc.contributor.author
Graff, Misa
Author
dc.contributor.author
Voruganti, Venkata Saroja
Admission date
dc.date.accessioned
2020-11-12T14:08:19Z
Available date
dc.date.available
2020-11-12T14:08:19Z
Publication date
dc.date.issued
2020
Cita de ítem
dc.identifier.citation
BMJ Open 2020;10:e033695
es_ES
Identifier
dc.identifier.other
10.1136/bmjopen-2019-033695
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/177688
Abstract
dc.description.abstract
Objectives Infant anthropometric growth varies across socioeconomic factors, including maternal education and income, and may serve as an indicator of environmental influences in early life with long-term health consequences. Previous research has identified sociodemographic gradients in growth with a focus on the first year and beyond, but estimates are sparse for growth before 6months. Thus, our objective was to examine the relationship between sociodemographic factors and infant growth patterns between birth and 5months of age.
Design Prospective cohort study.
Settings Low-income to middle-income neighbourhoods in Santiago, Chile (1991-1996).
Participants 1412 participants from a randomised iron-deficiency anaemia preventive trial in healthy infants.
Main outcome measures Longitudinal anthropometrics including monthly weight (kg), length (cm) and weight-for-length (WFL) values. For each measure, we estimated three individual-level growth parameters (size, timing and velocity) from SuperImposition by Translation and Rotation models. Size and timing changes represent vertical and horizontal growth curve shifts, respectively, and velocity change represents growth rate shifts. We estimated the linear association between growth parameters and gestational age, maternal age, education and socioeconomic position (SEP).
Results Lower SEP was associated with a slower linear (length) velocity growth parameter (-0.22, 95% CI -0.31 to -0.13)-outcome units are per cent change in velocity from the average growth curve. Lower SEP was associated with later WFL growth timing as demonstrated through the tempo growth parameter for females (0.25, 95% CI 0.05 to 0.42)-outcome units are shifts in days from the average growth curve. We found no evidence of associations between SEP and the weight size, timing or velocity growth rate parameters.
Conclusion Previous research on growth in older infants and children shows associations between lower SEP with slower length velocity. We found evidence supporting this association in the first 5months of life, which may inform age-specific prevention efforts aimed at infant length growth.
es_ES
Patrocinador
dc.description.sponsorship
American Heart Association
16PRE29200008
American Heart Association
15GRNT25880008
United States Department of Health & Human Services
National Institutes of Health (NIH) - USA
R01-HL-088530
R01-HD-033487