Author | dc.contributor.author | Pino, José Luis | |
Author | dc.contributor.author | Mujica, Verónica | |
Author | dc.contributor.author | Arredondo Olguín, Miguel Armando | |
Admission date | dc.date.accessioned | 2021-11-05T11:45:35Z | |
Available date | dc.date.available | 2021-11-05T11:45:35Z | |
Publication date | dc.date.issued | 2021 | |
Cita de ítem | dc.identifier.citation | Journal of Functional Foods 77 (2021) 104311 | es_ES |
Identifier | dc.identifier.other | 10.1016/j.jff.2020.104311 | |
Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/182589 | |
Abstract | dc.description.abstract | There is a growing interest in the use of functional foods. Studies indicate the contribution of β-glucans to
glycemic control, but few have evaluated integrally the effect of this soluble dietary fiber on appetite-regulating
hormones and microbiota in type-2 diabetes (T2D). We analyzed the effect of enriching a normal diet with oat
β-glucan in thirty-seven T2D subjects. For 12 weeks, subjects consumed daily oat β-glucan or microcrystalline
cellulose as control (5 g/day). We determined fasting glucose, C-peptide, insulin, HOMA, HbA1c, lipid profile,
ghrelin, leptin, GLP-1, PYY, caloric intake, and intestinal microbiota. HbA1c decreased in the β-glucan group.
Insulin, C-peptide and HOMA, Lactobacillus spp, and Butyrate-producing bacteria decreased in the β-glucan group
(p < 0.05). Leptin (p < 0.05), GLP-1 (p < 0.01) and PYY (p < 0.001) were different between groups. The intake of
5 g/oat β-glucan for 12 weeks can help improve glycemic control, increase the feeling of satiety, and promote
changes in the gut microbiota profile. | es_ES |
Patrocinador | dc.description.sponsorship | Micronutrient Laboratory, Human Nutrition Unit, Institute of Nutrition and Food Technology (INTA), Universidad de Chile | es_ES |
Lenguage | dc.language.iso | en | es_ES |
Publisher | dc.publisher | Elsevier | es_ES |
Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 United States | * |
Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/us/ | * |
Source | dc.source | Journal of Functional Foods | es_ES |
Keywords | dc.subject | Type-2 diabetes mellitus | es_ES |
Keywords | dc.subject | Dietary fiber | es_ES |
Keywords | dc.subject | Beta-glucans | es_ES |
Keywords | dc.subject | Oats | es_ES |
Keywords | dc.subject | Gut hormones | es_ES |
Keywords | dc.subject | Microbiota | es_ES |
Título | dc.title | Effect of dietary supplementation with oat beta-glucan for 3 months in subjects with type 2 diabetes: A randomized, double-blind, controlled clinical trial | es_ES |
Document type | dc.type | Artículo de revista | es_ES |
dc.description.version | dc.description.version | Versión publicada - versión final del editor | es_ES |
dcterms.accessRights | dcterms.accessRights | Acceso abierto | es_ES |
Cataloguer | uchile.catalogador | cfr | es_ES |
Indexation | uchile.index | Artículo de publícación WoS | es_ES |
Indexation | uchile.index | Artículo de publicación SCOPUS | es_ES |