Browsing by Author "201-0010793"
Now showing items 1-20 of 42
-
(SOC CHILENA QUIMICA, 2007-12)A novel approach to the development of anew class of HIV-1 RT inhibitors is reported. The 1-benzoyl-2-aryl-1H-benzimidazole series was designed as a combination of two previously reported active scaffolds, the benzimidazole ...
-
(BLACKWELL MUNKSGAARD, 2005-04)The title compound, C12H7NO3, consists of a chromone moiety substituted in position 3 with an acrylonitrile group in a Z configuration. The two planar groups are twisted with respect to one another. The only significant ...
-
(Bentham Science Publishers, 2003)The present review discusses the synthetic strategies of new ligands exhibiting mainly 5-HT1A binding affinities. Specifically we focused our attention in the synthesis of compounds structurally related to arylpiperazine, ...
-
(SOC BIOLGIA CHILE, 2008)This study describes the effect of novel 6-Arylbenzimidazo[1,2-c]quinazoline derivatives as tumor necrosis factor alpha (TNF-alpha) production inhibitors. The newly synthesized compounds were tested for their in vitro ...
-
(SOCIEDAD CHILENA DE QUIMICA, 2001-09)Activation parameters for the rotation around the methylene-nitrogen single bond found in a series of four 2,2'-disubstituted N-acetyl-N-phenylbenzylamines, dissolved in DMSO-d(6), were measured employing the temperature ...
-
(2013)A series of novel 2-pyridylbenzimidazole derivatives was rationally designed and synthesized based on our previous studies on benzimidazole 14, a CB1 agonist used as a template for optimization. In the present series, 21 ...
-
(PERGAMON-ELSEVIER SCIENCE LTD, 2008-08-15)This work presents the development of analytical methodologies by UV spectrophotometry and HPLC to characterize five nitroarylbenzimidazole derivatives with activity against Trypanosoma cruzi: NB, BNB, PNB, PMNB and PCNB. ...
-
(PERGAMON-ELSEVIER SCIENCE LTD, 2007-06-01)E)-Ethyl 3-(4-oxo-4H-chromen-3-yi)acrylate (3), (E)-3-(4-oxo-4H-chromen-3-yl)-2-propenenitrile (12) and their 5-hydroxy-derivatives 11 and 13 undergo alternative, solvent dependent, domino reactions with ethyl vinyl ether. ...
-
(PERGAMON-ELSEVIER SCIENCE LTD, 2002-09)A set of structurally related compounds incorporating a carbonyl group in the ortho position with regard to a phenol function were tested against the TA3 mouse carcinoma cell line and its multidrug-resistant variant ...
-
(Elsevier Ltd., 2006-02-28)A series of tricyclic hydroquinones, incorporating a carbonyl group in the ortho position relative to the phenol function, were tested as inhibitors of oxygen uptake against the TA3 mouse carcinoma cell line and its ...
-
(Elsevier Ltd., 2006-02-28)Abstract—A series of tricyclic hydroquinones, incorporating a carbonyl group in the ortho position relative to the phenol function, were tested as inhibitors of oxygen uptake against the TA3 mouse carcinoma cell line and ...
-
(ELSEVIER SCIENCE, 1998-08)The electrochemical reduction of four 2,5-dimethoxy nitrobenzene 6-substituted derivatives in aqueous and mixed media by cyclic voltammetry, tast and differential pulse polarography were studied. In aqueous media, pH > 8, ...
-
(ELSEVIER SCIENCE BV, 2009-08-15)The present study addresses the electrochemical behavior and the analytical applications of six 2-nitrophenylbenzimidazole derivatives with activity against Trypanosoma cruzi. When studied in a wide range of pH, by ...
-
(Universidad de ChileCyberDocs, 2009)
-
(Universidad de Chile, 2011)En la presente tesis se expone un estudio sintético orientado a la obtención de dos familias estructuralmente relacionadas al esqueleto de aril(alquil)piperazinil indoles. La familia (I): 1-bencil-3-[(4-aril-1-piperazini ...
-
(Universidad de Chile, 2008)La depresión es una grave patología neuropsiquiátrica caracterizada por síntomas de orden afectivo, cognitivo, motor y somático, la cual es desencadenada por una compleja interconexión de factores genéticos, de desarrollo ...
-
(Universidad de Chile, 2012)Estudios de funcionalización del 1H-indol, condujeron a la familia de N-{4-[4-(1H-Indol-3-carbonil)-1-piperazinil]-fenil}-arilamidas 6(a-h) (Familia I) como potenciales ligandos provistos de acción serotoninérgica en el ...
-
(Universidad de Chile, 2013)Estudios de funcionalización del 1H-indol-2-acido carboxílico, condujeron a la síntesis de una familia de compuestos N-{4-[4-(1H-Indol-2-carbonil)-1-piperazinil]-fenil}- arilamidas 4(a-h) con potencial actividad ...
-
(MARCEL DEKKER INC, 2003)Treatment of formylchromones, dissolved in 2-propanol with basic alumina at 75degreesC, selectively reduces the formyl group with good yields without any activation process of the alumina.
-
(TAYLOR & FRANCIS INC., 2005)The synthesis of 2-(2-nitrophenyl)-1H-benzimidazole (1), 1-benzoyl-2-(2-nitrophenyl)-1H -benzimidazole (2), and 1-acetyl-2-(2-nitrophenyl)-1H-benzimidazole ( 3) is reported. Stable radical anions (1(center dot-), 2(center ...
