Browsing by Author "XX596495"
Now showing items 1-9 of 9
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Yáñez López, José (Universidad de Chile, 2005)La proteína quinasa CK1 es una familia de proteínas a la que recientemente se la ha relacionado con el desarrollo embrionario. De esta familia se han clonado al menos siete isoformas (α, β, δ, ε, γ-1, γ-2 y γ-3). En esta ...
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Foerster Guzmán, Claudia (Universidad de Chile, 2006)La proteína CK1 es una familia de proteínas quinasa a la que recientemente se la ha relacionado con el desarrollo embrionario. De esta familia se han clonado al menos siete isoformas: CK1α, CK1β, CK1γ1, CK1γ2, CK1γ3, CK1δ ...
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Lucero, Claudia M. J.; Vega, Oscar A.; Osorio, Mariana M.; Tapia Pineda, Julio; Antonelli Anativia, Juan; Stein, Gary S.; Van Wijnen, Andre J.; Galindo, Mario A. (Wiley Periodicals, 2013)Runx2 regulates osteogenic differentiation and bone formation, but also suppresses pre-osteoblast proliferation by affecting cell cycle progression in the G1 phase. The growth suppressive potential of Runx2 is normally ...
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Rojas, Diego; Pérez Munizaga, Daniela A.; Centanin, Lazaro; Antonelli Anativia, Juan; Wappner, Pablo; Allende Connelly, Miguel; Reyes, Ariel E. (Elsevier B.V., 2006-08-15)Hypoxia-inducible factors (HIFs) regulate gene expression in response to hypoxia and in vertebrates they are known to participate in several developmental processes, including angiogenesis, vasculogenesis, heart and central ...
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Aguirre Gutiérrez, Celeste Rosa (Universidad de Chile, 2007)La vía de señalización del gen Wnt cumple importantes roles en el desarrollo y oncogénesis, es transducido por al menos dos vías: la vía canónica β-catenina dependiente y la cascada no canónica, independiente de β-catenina. ...
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Lizama, Carlos; Rojas Benitez, Diego; Antonelli Anativia, Juan; Ludwig, Andreas; Moreno, Ricardo D. (WILEY-BLACKWELL, 2012-02)Germ cell apoptosis is important to regulate sperm production in the mammalian testis, but the molecular mechanisms underlying apoptosis are still poorly understood. We have recently shown that in vitro, etoposide induces ...
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Alvarez, Alhejandra; Uribe, Felipe; Canales, Jimena; Romero, Cristóbal; Soza, Andrea; Peña, María A.; Antonelli Anativia, Juan; Almarza, Oscar; Cerda Arancibia, Óscar; Toledo Araya, Héctor (Frontiers Media SA, 2017)In order to establish infection, bacterial pathogens modulate host cellular processes by using virulence factors, which are delivered from the bacteria to the host cell leading to cellular reprogramming. In this context, ...
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Varela Figueroa, Nelson; Aránguiz Quezada, Katherine Alejandra; Lizama, Carlos; Sepúlveda, Hugo; Antonelli Anativia, Juan; Thaler, Román; Moreno, Ricardo D.; Montecino, Martín; Stein, Gary S.; Van Wijnen, Andre; Galindo Díaz, Mario (Wiley-Blackwell, 2016)Epigenetic mechanisms mediate the acquisition of specialized cellular phenotypes during tissue development, maintenance and repair. When phenotype-committed cells transit through mitosis, chromosomal condensation counteracts ...
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Vega, Oscar A.; Lucero, Claudia M. J.; Araya, Héctor F.; Jerez, Sofía; Tapia Pineda, Julio; Antonelli Anativia, Juan; Salazar Onfray, Flavio; Heras Aliciardi, Facundo las; Thaler, Roman; Riester, Scott M.; Stein, Gary S.; van Wijnen, Andre J.; Galindo Díaz, Mario (Wiley, 2017)Osteosarcoma is the most common malignant bone tumor in children and adolescents. Metastasis and poor responsiveness to chemotherapy in osteosarcoma correlates with over-expression of the runt-related transcription factor ...