Browsing by Author "XX631157"
Now showing items 1-17 of 17
-
(BIOMED Central Ltd., 2017)Background: CLCA is a family of metalloproteases that regulate Ca2+-activated Cl- fluxes in epithelial tissues. In HEK293 cells, CLCA1 promotes membrane expression of an endogenous Anoctamin 1 (ANO1, also termed ...
-
(2007)Evidence from several areas of neuroscience has led to the notion that copper and zinc could be modulators of neuronal excitability. In order to contribute to test this idea, we characterized the changes induced by these ...
-
(Wiley & Sons, 2015)Copper, an ion with many important metabolic functions, has also been proposed to have a role as modulator on neuronal function, mostly based on its effects on voltage- and neurotransmitter-gated conductance as well as ...
-
Cyclic AMP cascade mediates the inhibitory odor response of isolated toad olfactory receptor neurons (AMER PHYSIOLOGICAL, 2005-09)Odor stimulation may excite or inhibit olfactory receptor neurons (ORNs). It is well established that the excitatory response involves a cyclic AMP (cAMP) transduction mechanism that activates a nonselective cationic cyclic ...
-
(2006)Based on indirect evidence, a role for synaptically released copper and zinc as modulators of neuronal activity has been proposed. To test this proposal directly, we studied the effect of copper, zinc, and other ...
-
(Company of Biologists Ltd., 2017)Hereditary spastic paraplegias (HSPs) are characterized by spasticity and weakness of the lower limbs, resulting from length-dependent axonopathy of the corticospinal tracts. In humans, the HSP-related atlastin genes ...
-
(Soc Neuroscience, 2017-06-07)The mechanisms that power the physiological events occurring in cilia, flagella, and microvilli are of fundamental importance for the functions of these important and ubicuous organelles. The olfactory epithelium is mostly ...
-
(Universidad de ChileCyberDocs, 2010)Los sistemas biológicos de transducción de señales comparten mecanismos celulares conservados en diversos organismos. El estudio de los sistemas visuales de insectos, como el de la mosca Drosophila melanogaster, ha permitido ...
-
(2013)Phototransduction, the mechanism underlying the electrical response to light in photoreceptor cells, has been thoroughly investigated in Drosophila melanogaster, an essential model in signal transduction research. These ...
-
(BLACKWELL, 2007-09-03)Olfactory sensory neurons respond to odorants increasing Ca2+ concentrations in their chemosensory cilia. Calcium enters the cilia through cAMP-gated channels, activating Ca2+-dependent chloride or potassium channels. ...
-
Putative ClC-2 chloride channel mediates inward rectification in Drosophila retinal photoreceptors (SPRINGER, 2005-10)We report that Drosohhila retinal photoreceptors express inwardly rectifying chloride channels that seem to be orthologous to mammalian CIC-2 inward rectifier channels. We measured inwardly rectifying Cl- currents in ...
-
(BLACKWELL PUBLISHING, 2009-01-09)The brain uses massive amounts of oxygen, generating large quantities of reactive oxygen species (ROS). Because of its lipid composition, rich in unsaturated fatty acids, the brain is especially vulnerable to ROS. ...
-
(BLACKWELL, 2006-07)The brain uses massive amounts of oxygen, generating large quantities of reactive oxygen species (ROS). Because of its lipid composition, rich in unsaturated fatty acids, the brain is especially vulnerable to ROS. Furthermore, ...
-
(Biomed Central, 2016)Background: Odor transduction, occurring in the chemosensory cilia of vertebrate olfactory sensory neurons, is triggered by guanosine triphosphate-coupled odor receptors and mediated by a cyclic adenosine monophosphate ...
-
(Oxford Univ Press, 2016)
-
(2014)Growing evidence suggests that the main olfactory epithelium contains a subset of olfactory sensory neurons (OSNs) responding to pheromones. One candidate subpopulation expresses the calcium activated cation channel TRPM5 ...
-
(AMER PHYSIOLOGICAL SOC, 2009-03-02)Delgado R, Bacigalupo J. Unitary recordings of TRP and TRPL channels from isolated Drosophila retinal photoreceptor rhabdomeres: activation by light and lipids. J Neurophysiol 101: 2372–2379, 2009. First published March ...
