Browsing by Author "XX676164"

Now showing items 1-6 of 6

    • Apoptosis is directly related to intracellular amyloid accumulation in a cell line derived from the cerebral ... 
      Arriagada Abarzúa, Christian; Bustamante, Miguel; Atwater Ransom, Illani; Rojas, Eduardo; Caviedes Codelia, Raúl; Caviedes Fernández, Pablo (ELSEVIER, 2010)
      Human Down syndrome (DS) represents the most frequent cause of mental retardation associated to a genetic condition. DS also exhibits a characteristic early onset of neuropathology indistinguishable from that observed ...
    • Efecto del factor de crecimiento endotelio vascular (VEGF) sobre perforaciones timpánicas en ratas Long-Evans 
      Zúñiga Pino, Jorge; Maass Oñate, Juan; Arriagada Abarzúa, Christian (2007)
      Introducción: La angiogénesis es el desarrollo de nuevos vasos sanguíneos desde una red vascular existente, contempla una secuencia de eventos complejos y es fundamental en el proceso reparativo. Existen múltiples factores ...
    • Isolation of Viable Porcine Islets by Selective Osmotic Shock Without Enzymatic Digestion 
      Atwater Ransom, Illani; Guajardo, M.; Caviedes Fernández, Pablo; Jeffs, S.; Parrau, D.; Valencia, M.; Romero, C.; Arriagada Abarzúa, Christian; Caamaño, Edgardo; Salas, A.; Olguín, F.; Atlagich, Miljenko; Maas, R.; Mears, David; Rojas, Eduardo (ELSEVIER, 2010)
      Islet transplantation is a potential cure for type 1 diabetes, but clinical results have been disappointing. Currently, islet isolation is by enzymatic digestion of the pancreas which has significant pitfalls: warm ...
    • Neuronal dysfunction in Down syndrome: Contribution of neuronal models in cell culture 
      Saud, Katherine; Arriagada Abarzúa, Christian; Cárdenas, Ana María; Shimahara, Takeshi; Allen, David D.; Caviedes Codelia, Raúl; Caviedes Fernández, Pablo (ELSEVIER, 2006-05)
      Down syndrome (DS) in humans, or trisomy of autosome 21, represents the hyperdiploidy that most frequently survives gestation, reaching an incidence of I in 700 live births. The condition is associated with multisystemic ...
    • Small-molecule aggregation inhibitors reduce excess amyloid in a trisomy 16 mouse cortical cell line 
      Paula Lima, Andrea; Arriagada Abarzúa, Christian; Toro Sánchez, Rodrigo; Cárdenas, Ana María; Caviedes Codelia, Raúl; Ferreira, Sergio T.; Caviedes Fernández, Pablo (SOC BIOLGIA CHILE, 2008)
      We have previously characterized a number of small molecule organic compounds that prevent the aggregation of the β-amyloid peptide and its neurotoxicity in hippocampal neuronal cultures. We have now evaluated the effects ...
    • The absence of dysferlin induces the expression of functional connexin-based hemichannels in human myotubes 
      Cea Pisani, Luis Andrés; Bevilacqua, Jorge; Arriagada Abarzúa, Christian; Cárdenas, Ana María; Bigot, Anne; Mouly, Vincent; Sáez, Juan C.; Caviedes Fernández, Pablo (2016)
      Background: Mutations in the gene encoding for dysferlin cause recessive autosomal muscular dystrophies called dysferlinopathies. These mutations induce several alterations in skeletal muscles, including, inflammation, ...