Browsing by Author "XX676987"

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    • Absorption of Iron from Ferritin Is Independent of Heme Iron and Ferrous Salts in Women and Rat Intestinal Segments 
      Theil, Elizabeth C.; Chen, Huijun; Miranda, Constanza; Janser, Heinz; Elsenhans, Bernd; Núñez González, Marco; Pizarro Aguirre, Fernando; Schümann, Klaus (AMER SOC NUTRITION, 2012-03)
      Ferritin iron from food is readily bioavailable to humans and has the potential for treating iron deficiency. Whether ferritin iron absorption is mechanistically different from iron absorption from small iron complexes/salts ...
    • Acute Copper and Ascorbic Acid Supplementation Inhibits Non-heme Iron Absorption in Humans 
      Olivares Grohnert, Manuel; Figueroa Donoso, Constanza; Pizarro Aguirre, Fernando (Humana Press, 2016)
      The objective of the study is to determine the effect of copper (Cu) plus the reducing agent ascorbic acid (AA) on the absorption of non-heme iron (Fe). Experimental study with block design in which each subject was his ...
    • Acute inhibition of iron absorption by zinc 
      Pizarro Aguirre, Fernando; Pizarro Aguirre, Fernando; Gaitán, Diego; Ruz, Manuel (PERGAMON-ELSEVIER SCIENCE LTD., 2007-05)
      Iron and zinc deficiencies are the most common nutritional deficiencies worldwide. Combined zinc and iron supplementation is one of the strategies used to prevent these deficiencies. Zinc has an inhibitory effect on iron ...
    • Administration of high doses of copper to capuchin monkeys does not cause liver damage but induces ... 
      Araya, Magdalena; Núñez, Héctor; Pavez, Leonardo; Arredondo, Miguel; Méndez, Marco; Cisternas, Felipe; Pizarro Aguirre, Fernando; Sierralta, Walter; Uauy Dagach-Imbarack, Ricardo; González, Mauricio (2012)
      Liver cells respond to copper loading upregulating protective mechanisms. However, to date, except for liver content, there are no good indicators that identify individuals with excess liver copper. We hypothesized that ...
    • Administration of High Doses of Copper to Capuchin Monkeys Does Not Cause Liver Damage but Induces ... 
      Araya, Magdalena; Núñez, Héctor; Pavez, Leonardo; Arredondo Olguín, Miguel Armando; Méndez, Marco; Cisternas, Felipe; Pizarro Aguirre, Fernando; Sierralta, Walter; Uauy Dagach-Imbarack, Ricardo; González Canales, Mauricio (American Society for Nutrition, 2012)
      Liver cells respond to copper loading upregulating protective mechanisms. However, to date, except for liver content, there are no good indicators that identify individuals with excess liver copper. We hypothesized that ...
    • Ascorbyl palmitate enhances iron bioavailability in iron-fortified bread 
      Pizarro Aguirre, Fernando; Olivares Grohnert, Manuel; Hertrampf, Eva; Núñez, Silvia; Tapia, Marcelo; Cori, Héctor; López de Romaña, Daniel (AMER SOC CLINICAL NUTRITION, 2006-10)
      Background: One of the strategies to control iron deficiency anemia is the fortification of food with iron. A mechanism for improving the bioavailability of iron is to add an iron absorption promoter. Objective: The ...
    • Assessment of dietary intake and urinary excretion of sodium and potassium in adults Evaluación de la ingesta ... 
      Cornejo, Karen; Pizarro Aguirre, Fernando; Atalah Samur, Eduardo; Galgani Fuentes, José (Sociedad Medica de Santiago, 2014)
      © 2013, Sociedad Medica de Santiago, All rights reserved. Background: Hypertension is associated with elevated sodium and low potassium intakes. The determination of sodium and potassium intake by dietary records is ...
    • Bioavailability of elemental iron powder in white wheat bread 
      Walter, Tomas; Pizarro Aguirre, Fernando; Abrams, Steven A.; Boy, Erick (NATURE PUBLISHING GROUP, 2004-03)
      Objective: Iron fortification of wheat flour is widely used. In most cases, elemental iron powders are utilized as fortificants due to their lower cost and few, if any, sensory problems. However, their bioavailability is ...
    • Bioavailability of Stabilised Ferrous Gluconate with Glycine in Fresh Cheese Matrix: a Novel Iron Compound ... 
      Pizarro Aguirre, Fernando; Boccio, José; Salgueiro, María; Olivares Grohnert, Manuel; Carmuega, Esteban; Weill, Ricardo; Marque, Sebastien; Frereux, Marine; Noirt, Florence (Springer, 2013)
      Iron fortification of foods continues to be one of the preferred ways of improving the iron status of the population. Dairy product is a common product in the diet; therefore, it is a plausible vehicle for iron ...
    • Blood biochemical indicators in young and adult Cebus apella of both sexes 
      Núñez, H.; Araya, Matilde; Cisternas, F.; Arredondo, M.; Méndez, M.; Pizarro Aguirre, Fernando; Ortiz, A.; Ortiz, R.; Olivares, M. A (2008)
      Background: A frequent drawback in physiology of non-human primates is that normal values for a variety of indicators (haematological, biochemical and others) are scant. Methods: We report here the blood values in a series ...
    • Body mass index, iron absorption and iron status in childbearing age women 
      Mujica Coopman, María; Brito, Alex; López de Romaña, Daniel; Pizarro Aguirre, Fernando; Olivares Grohnert, Manuel (Elsevier, 2015)
      Background: The prevalence of obesity has increased at an alarming rate worldwide. Some studies have observed an association between iron (Fe) deficiency (ID) and obesity, however more research is needed. Objective: To ...
    • Caco-2 intestinal epithelial cells absorb soybean ferritin by mu(2) (AP2)-dependent endocytosis 
      San Martín Rovirosa, Carol; Garri, Carolina; Pizarro Aguirre, Fernando; Walter, Tomas; Theil, Elizabeth C.; Núñez González, Marco (2008)
      Iron deficiency, a condition currently affecting similar to 3 billion people, persists in the 21st century despite half a millennium of medical treatment. Soybean ferritin (SBFn), a large, stable protein nanocage around a ...
    • Caco-2 Intestinal Epithelial Cells Absorb Soybean Ferritin by u2 (AP2)-Dependent Endocytosis1,2 
      San Martín Rovirosa, Carol; Garri, Carolina; Pizarro Aguirre, Fernando; Walter, Tomas; Theil, Elizabeth C.; Núñez González, Marco (Journal of Nutrition, 2008-05)
      Iron deficiency, a condition currently affecting ;3 billion people, persists in the 21st century despite half a millennium of medical treatment. Soybean ferritin (SBFn), a large, stable protein nanocage around a mineral ...
    • Calcium does not inhibit the absorption of 5 milligrams of nonheme or heme iron at doses less than 800 ... 
      Gaitán, Diego; Flores, Sebastián; Saavedra, Pía; Miranda, Constanza; Olivares, Manuel; Arredondo, Miguel; López de Romaña, Daniel; Lönnerdal, Bo; Pizarro Aguirre, Fernando (2011)
      Calcium is the only known component in the diet that may affect absorption of both nonheme and heme iron. However, the evidence for a calcium effect on iron absorption mainly comes from studies that did not isolate the ...
    • Case study of complaints on drinking water quality: Relationship to copper content? 
      Pizarro Aguirre, Fernando; Araya, Magdalena; Vásquez, Marcela; Lagos, Gustavo; Olivares, Manuel; Méndez, Marco A.; Leyton Dinamarca, Bárbara; Reyes, Arturo; Letelier, Victoria; Uauy Dagach-Imbarack, Ricardo (Humana Press Inc., 2007)
      Several families of Talca city, Chile complained to health authorities for what they attributed to consumption of copper (Cu)-contaminated drinking water. We assessed the situation 6-12 mo after the initiation of complaints ...
    • Changes in Bone Mineral Density, Body Composition and Adiponectin Levels in Morbid Obese Patients after ... 
      Carrasco, Fernando; Ruz, Manuel; Rojas Mondaca, Pamela; Csendes Juhasz, Attila; Rebolledo Acevedo, Annabella; Codoceo, Juana; Inostroza Escobar, Jorge; Basfi-fer Obregón, Karen; Papapietro Vallejo, Karin; Rojas Caro, Jorge; Pizarro Aguirre, Fernando; Ordóñez Pizarro, Fernando (Springer, 2008)
      Introduction Gastric bypass surgery (GBP) is increasingly used as a treatment option in morbid obesity. Little is known about the effects of this surgery on bone mineral density (BMD) and the underlying mechanisms. To ...
    • Changes in bone mineral density, body composition and adiponectin levels in morbidly obese patients after ... 
      Carrasco, Fernando; Ruz, Manuel; Arenas Rojas, Pamela; Csendes Juhasz, Attila; Rebolledo, Annabella; Codoceo, Juana; Inostroza, Jorge; Basfi-fer Obregón, Karen; Papapietro Vallejo, Karin; Vargas Rojas, Jorge Antonio; Pizarro Aguirre, Fernando; Olivares, Manuel (2009)
      Background: Gastric bypass surgery (GBP) is increasingly used as a treatment option in morbid obesity. Little is known about the effects of this surgery on bone mineral density (BMD) and the underlying mechanisms. To ...
    • Chaperones CCS, ATOX and COXIV responses to copper supplementation in healthy adults 
      Araya, Magdalena; Andrews, Mónica; Pizarro Aguirre, Fernando; Arredondo Olguín, Miguel Armando (Springer, 2012-04)
      Assessment of proteins in blood and other tissues has failed to identify markers of early copper effects on health. Studies in animal models show that chaperone of SOD (CCS) respond to changes of copper status. Evidence ...
    • Community-based randomized double-blind study of gastrointestinal effects and copper exposure in drinking water 
      Araya, Magdalena; Olivares Grohnert, Manuel; Pizarro Aguirre, Fernando; Llanos, Adolfo; Figueroa, Guillermo; Uauy Dagach-Imbarack, Ricardo (US DEPT HEALTH HUMAN SCIENCES PUBLIC HEALTH SCIENCE, 2004-07)
      We assessed gastrointestinal effects in 1,365 adults exposed to either < 0.01 (controls), 2, 4, or 6 mg copper/L of drinking water for 2 months in a randomized, double-blind community-based study. The risk of symptoms ...
    • Confirmation of an acute no-ob served-adverse-effect and low-observed-adverse-effect level for copper in ... 
      Araya, Magdalena; Chen, Bingheng; Klevay, Leslie M.; Strain, J. J.; Johnson, Luann; Robson, Paula; Shi, Wei; Nielsen, Forrest; Zhu, Huigang; Olivares Grohnert, Manuel; Pizarro Aguirre, Fernando; Haber, Lynne T. (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2003-12)
      In a double blind, 3 x 3 factorial (volume x dose) study, 70 adult females (18-60 years of age) at four different international sites (total pooled n = 269) were given 100, 150, or 200 ml of bottled drinking water with ...