Browsing by Author "XX677272"
Now showing items 1-20 of 25
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(AMER ASSOC ADVANCEMENT SCIENCE, 1999-09-17)Maxi-K channels consist of a pore-forming alpha subunit and a regulatory beta subunit, which confers the channel with a higher Ca2+ sensitivity. Estradiol bound to the beta subunit and activated the Maxi-K channel (hSlo) ...
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(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2008-04-11)The Arabidopsis thaliana AtHMA1 protein is a member of the P-IB-ATPase family, which is implicated in heavy metal transport. However, sequence analysis reveals that AtHMA1 possesses a predicted stalk segment present in ...
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(AMER PHYSIOLOGICAL SOC, 2002-03)We studied the effect of H2O2 on the gating behavior of large-conductance Ca2+-sensitive voltage-dependent K+ (K-V,K-Ca) channels. We recorded potassium currents from single skeletal muscle channels incorporated into ...
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(Elsevier Ltd, 1998)Calcium-activated potassium channels are fundamental regulators of neuronal excitability, participating in interspike interval and spike-frequency adaptation. For large-conductance calcium-activated potassium (BK) channels, ...
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(Society of Biology of Chile, 2003)The well-established trophic role of CNTF upon neurons led to performing clinical trials in patients of neurodegenerative diseases. However, trials were suspended due to side effects such as severe weight loss, hyperalgesia, ...
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(ELSEVIER SCIENCE BV, 2004-12)Ciliary neurotrophic factor (CNTF) is a cytokine whose neurotrophic and differentiating effects over cells in the central nervous system (CNS) have been clearly demonstrated. This article summarizes the general characteristics ...
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(1993)A low conductance calcium‐activated K+ channel is thought to regulate the rate of firing of several excitable cells. In skeletal muscle the expression of this channel is under nerve control. Previously, we reported that ...
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(2007)Evidence from several areas of neuroscience has led to the notion that copper and zinc could be modulators of neuronal excitability. In order to contribute to test this idea, we characterized the changes induced by these ...
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(Wiley & Sons, 2015)Copper, an ion with many important metabolic functions, has also been proposed to have a role as modulator on neuronal function, mostly based on its effects on voltage- and neurotransmitter-gated conductance as well as ...
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(Humana Press, 1997)Investigation of phototransduction in invertebrate photoreceptors has revealed many physiological and biochemical features of fundamental biological importance. Nonetheless, no complete picture of phototransduction has yet ...
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(2006)Based on indirect evidence, a role for synaptically released copper and zinc as modulators of neuronal activity has been proposed. To test this proposal directly, we studied the effect of copper, zinc, and other ...
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(Soc Neuroscience, 2017-06-07)The mechanisms that power the physiological events occurring in cilia, flagella, and microvilli are of fundamental importance for the functions of these important and ubicuous organelles. The olfactory epithelium is mostly ...
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(Wiley, 2020)Cells possess a variety of organelles with characteristic structure and subcellular localization intimately linked to their specific function. While most are intracellular and found in virtually all eukaryotic cells, there ...
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(1983)The interaction of Ca2+ and Ba2+ with a Ca2+-activated K+ channel from rabbit skeletal muscle membranes is studied in planar lipid bilayers. At [Ca2+]≥100 µM in the cis side (the side to which the vesicles are added) and ...
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Light-dependent channels from excised patches of Limulus ventral photoreceptors are opened by cGMP (National Academy of Sciences, 1991)The identity of the second menenger that directly activates the light-dependent conductance in invertebrate photoreceptors remains unclear; the available evidence provides some support for cGMP and Ca2+. To resolve this ...
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(The Rockefeller University, 1999)Using Ba2 1 as a probe, we performed a detailed characterization of an external K 1 binding site located in the pore of a large conductance Ca2 1-activated K 1 (BKCa) channel from skeletal muscle incorporated into planar ...
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(1993)Microcin E492, a polypeptide antibiotic, has been shown to have an Mr, of 6,000 by urea-SDS-polyacrylamide gel electrophoresis of the fluorescently labelled compound. It is known that the bactericidal action of microcin ...
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(Springer, 2014)Copper plays a key role in aerobic cell physiology mainly related to mitochondrial metabolism. This element is also present at higher than basal levels in some central nuclei and indeed, current evidence support copper’s ...
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(1991)The properties of light-dependent channels in Limulus ventral photoreceptors have been studied in cell-attached patches. Two sizes of single-channel events are seen during illumination. Previous work has characterized the ...
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(Kluwer Academic/Plenum Publishers, 1996)1. Expression of the apamin-sensitive K+ channel (SK+) in rat skeletal muscle is neurally regulated. The regulatory effect of the nerve over the expression of some muscle ion channels has been attributed to the electrical ...
