Browsing by Title

Now showing items 43856-43875 of 92550

    • Genome-wide association analysis reveals loci associated with resistance against Piscirickettsia salmonis ... 
      Correa, Katharina; Lhorente, Jean Paul; López, María E.; Bassini, Liane; Naswa, Sudhir; Deeb, Nader; Di Genova, Alex; Maass Sepúlveda, Alejandro; Davidson, William S.; Yáñez López, José (BioMed Central, 2015)
      Background: Pisciricketssia salmonis is the causal agent of Salmon Rickettsial Syndrome (SRS), which affects salmon species and causes severe economic losses. Selective breeding for disease resistance represents one approach ...
    • Genome-Wide Association Study (GWAS) for Growth Rate and Age at Sexual Maturation in Atlantic Salmon (Salmo salar) 
      Gutiérrez, Alejandro P.; Yáñez López, José; Fukui, Steve; Swift, Bruce; Davidson, William S. (Public Library Science, 2015)
      Early sexual maturation is considered a serious drawback for Atlantic salmon aquaculture as it retards growth, increases production times and affects flesh quality. Although both growth and sexual maturation are thought ...
    • A genome-wide association study identifies multiple loci for variation in human ear morphology 
      Adhikari, Kaustubh; Reales, Guillermo; Smith, Andrew J.P.; Konka, Esra; Palmen, Jutta; Quinto Sánchez, Mirsha; Acuña Alonzo, Víctor; Jaramillo, Claudia; Arias, William; Fuentes, Macarena; Pizarro, María; Barquera Lozano, Rodrigo; Macín Pérez, Gastón; Gómez Valdés, Jorge; Villamil Ramírez, Hugo; Hunemeier, Tábita; Ramallo, Virginia; Silva de Cerqueira, Caio C.; Hurtado, Malena; Villegas, Valeria; Granja, Vanessa; Gallo, Carla; Poletti, Giovanni; Schuler Faccini, Lavinia; Salzano, Francisco M.; Bortolini, Maria Cátira; Canizales Quinteros, Samuel; Rothhammer Engel, Francisco; Bedoya, Gabriel; Calderón, Rosario; Rosique, Javier; Cheeseman, Michael; Bhutta, Mahmood F.; Humphries, Steve E.; González José, Rolando; Headon, Denis; Balding, David; Ruiz Linares, Andrés (Nature Publishing, 2015)
      Here we report a genome-wide association study for non-pathological pinna morphology in over 5,000 Latin Americans. We find genome-wide significant association at seven genomic regions affecting: lobe size and attachment, ...
    • Genome-wide association study identifying novel variant for fasting insulin and allelic heterogeneity in ... 
      Buchanan, Victoria L.; Wang, Yujie; Blanco, Estela; Graff, Mariaelisa; Albala Brevis, Cecilia; Burrows Argote, Raquel; Santos, José L.; Ángel, Barbara; Lozoff, Betsy; Voruganti, Venkata Saroja; Guo, Xiuqing; Taylor, Kent D.; Chen, Yii-Der Ida; Yao, Jie; Tan, Jingyi; Downie, Carolina; Highland, Heather M.; Justice, Anne E.; Gahagan, Sheila; North, Kari E. (Wiley, 2020)
      Background The genetic underpinnings of glycemic traits have been understudied in adolescent and Hispanic/Latino (H/L) populations in comparison to adults and populations of European ancestry. Objective To identify genetic ...
    • Genome-wide circulating microRNA expression profiling reveals potential biomarkers for amyotrophic lateral ... 
      Matamala, José Manuel; Arias Carrasco, Raul; Sánchez, Carolina; Uhrig, Markus; Bargsted, Leslie; Matus, Soledad; Maracaja Coutinho, Vinicius; Abarzua, Sebastián; Van Zundert, Brigitte; Verdugo Latorre, Renato; Manque, Patricio; Hetz Flores, Claudio (Elsevier, 2018)
      The occurrence of mutations of TDP-43, FUS, and C9ORF72 in amyotrophic lateral sclerosis (ALS) suggests pathogenic alterations to RNA metabolism and specifically to microRNA (miRNA) biology. Moreover, several ALS-related ...
    • Genomewide single nucleotide polymorphism discovery in Atlantic salmon (Salmo salar): validation in wild ... 
      Yáñez López, José; Naswa, S.; López, M. E.; Bassini, Liane; Correa, K.; Gilbey, J.; Bernatchez, L.; Norris, A.; Lhorente, Jean Paul; Schnable, P. S.; Newman, S.; Mileham, A.; Deeb, N.; Di Genova, Alex; Maass Sepúlveda, Alejandro (2016)
      A considerable number of single nucleotide polymorphisms (SNPs) are required to elucidate genotype-phenotype associations and determine the molecular basis of important traits. In this work, we carried out de novo SNP ...
    • Genome‑scale comparative analysis for host Resistance against sea lice between Atlantic salmon and rainbow trout 
      Cáceres, Pablo; Barría, Agustín; Christensen, Kris A.; Bassini Ney, Liane; Correa, Katharina; García, Baltasar; Lhorente Causade, Jean Paul; Yáñez López, José Manuel (Nature Research, Germany, 2021)
      Sea lice (Caligus rogercresseyi) is an ectoparasite which causes major production losses in the salmon aquaculture industry worldwide. Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss) are two of the ...
    • Genomic analysis of the diversity, antimicrobial resistance and virulence potential of clinical campylobacter ... 
      Bravo, Verónica; Katz Zondek, Assaf; Porte, Lorena; Weitzel, Thomas; Varela, Carmen; González Escalona, Narjol; BlondelI, Carlos J. (Public Library Science, 2021)
      Campylobacter jejuni and Campylobacter coli are the leading cause of human gastroenteritis in the industrialized world and an emerging threat in developing countries. The incidence of campylobacteriosis in South America ...
    • Genomic analysis of the domestication and post-Spanish conquest evolution of the llama and alpaca 
      Fan, Ruiwen; Gu, Zhongru; Guang, Xuanmin; Marín, Juan Carlos; Varas, Valeria; González Pérez, Benito; Wheeler, Jane C.; Hu, Yafei; Li, Elri; Sun, Xiaohui; Yang, Xukui; Zhang, Chi; Gao, Wenjun; He, Junping; Munch, Kasper; Corbett-Detig, Russel; Barbato, Mario; Pan, Shengkai; Zhan, Xiangjiang; Bruford, Michael W.; Dong, Changsheng (BMC, 2020)
      Background Despite their regional economic importance and being increasingly reared globally, the origins and evolution of the llama and alpaca remain poorly understood. Here we report reference genomes for the llama, and ...
    • Genomic and phenotypic comparison between similar wine yeast strains of Saccharomyces cerevisiae from ... 
      Salinas, F.; Mandakovic Seyler, Dinka; Urzúa Tobar, Ulises; Massera, A.; Miras, S.; Combina, M.; Ganga, M. Angélica; Martínez, C. (2010)
      Aims: To study genomic and phenotypic changes in wine yeasts produced in short time periods analysing yeast strains possibly derived from commercial strains recently dispersed. Methods and Results: We conducted a genomic ...
    • Genomic and SNP Analyses Demonstrate a Distant Separation of the Hospital and Community-Associated Clades ... 
      Galloway Peña, Jessica; Roh, Jung Hyeob; Latorre, Mauricio; Qin, Xiang; Murray, Barbara E. (PUBLIC LIBRARY SCIENCE, 2012-01-26)
      Recent studies have pointed to the existence of two subpopulations of Enterococcus faecium, one containing primarily commensal/community-associated (CA) strains and one that contains most clinical or hospital-associated ...
    • Genomic characterization of the non-O1/non-O139 Vibrio cholerae strain that caused a gastroenteritis outbreak ... 
      Arteaga Ortega, Mónica; Velasco, Juliana; Rodríguez, Shelly; Vidal, Maricel; Arellano, Carolina; Silva Ojeda, Francisco; Carreño Marquez, Leandro; Vidal Álvarez, Roberto; Montero, David (Microbiology Society, 2020)
      Vibrio cholerae is a human pathogen, which is transmitted by the consumption of contaminated food or water. V. cholerae strains belonging to the serogroups O1 and O139 can cause cholera outbreaks and epidemics, a severe ...
    • Genomic compatibility between two phyllotine rodent species evaluated through their hybrids 
      Walker Bozzo, Laura; Rojas, Mariana; Flores Carrasco, Sergio; Spotorno Oyarzún, Ángel; Manríquez Soto, Germán Raúl (1999)
      In order to investigate the genomic compatibility between allopatric rodent species, Phyllotis durivini and Pliyllotis mugister, we have studied several cytogenetic and reproductive features of their laboratory hybrids. ...
    • Genomic determinants of hepatitis C virus antiviral therapy outcomes: toward individualized treatment 
      Venegas Santos, Mauricio; Brahm Barril, Javier; Villanueva Arancibia, Rodrigo (2012)
      Hepatitis C virus (HCV) is an important global health problem with an estimated prevalence of more than 170 million infected individuals worldwide. Currently, the standard antiviral therapy, based on pegylated interferon ...
    • Genomic diversity of listeria monocytogenes isolated from clinical and non-clinical samples in Chile 
      Toledo, Viviana; Den Bakker, Henk; Hormazábal, Juan; González-Rocha, Gerardo; Bello-Toledo, Helia; Toro, Magaly; Moreno-Switt, Andrea (MDPI AG, 2018)
      Listeria monocytogenes is the causative agent of listeriosis, which is an uncommon but severe infection associated with high mortality rates in humans especially in high-risk groups. This bacterium survives a variety of ...
    • Genomic epidemiology of shiga toxin-producing escherichia coli isolated from the livestock-food-human ... 
      Galarce Gálvez, Nicolás Elías; Sánchez García, Fernando Alonso; Escobar González, Beatriz del Carmen; Lapierre Acevedo, Lisette Nicole; Cornejo Kelly, Javiera; Alegría Morán, Raúl Alejandro; Neira Ramírez, Víctor Manuel; Martínez Moncada, Víctor Agustín; Johnson, Timothy; Fuentes Castillo, Danny; Sano, Elder; Lincopan, Nilton (MDPI, 2021)
      Simple Summary Shiga toxin-producing Escherichia coli (STEC) are zoonotic pathogens that cause food-borne diseases in humans, where cattle and derived products play a key role as reservoirs and vehicles. We analyzed the ...
    • Genomic identification of recent positive selection in populations from Andean highlands and south-central Chile 
      Contreras, Paloma S.; Blanco, Alejandro E.; Moreno Estrada, Andrés; Sandoval, Karla; Eng, Celeste; Huntsman, Scott; Burchard, Esteban G.; Gignoux, Christopher; Bustamante, Carlos; Llop Romero, Elena; Moraga, Mauricio; Verdugo, Ricardo (WILEY-BLACKWELL, 2016)
    • Genomic imprinting and embryonic development Impronta genómica y desarrollo embrionario 
      Reig, German; Concha, Miguel L. (2012)
      SUMMARY: In diploid organisms, autosomal genes are composed of two copies, or alleles, inherited from both parents at fertilization. For the vast majority of autosomal genes, expression occurs from both alleles simultaneously. ...
    • Genomic insights into the iron uptake mechanisms of the biomining microorganism Acidithiobacillus ferrooxidans 
      Quatrini, Raquel; Jedlicki Corbeaux, Eugenia; Holmes, David S. (SPRINGER HEIDELBERG, 2005-12)
      Commercial bioleaching of copper and the biooxidation of gold is a cost-effective and environmentally friendly process for metal recovery. A partial genome sequence of the acidophilic, bioleaching bacterium Acidithiobacillus ...
    • Genomic insights into the origin and diversification of late maritime hunter-gatherers from the chilean Patagonia 
      Fuente, Constanza de la; Galimany, Jacqueline; Blanco, Alejandro E.; Contreras, Paloma; Llop Romero, Elena; Verdugo, Ricardo; Moraga, Mauricio (Natl Acad Sciences, 2018)
      Patagonia was the last region of the Americas reached by humans who entered the continent from Siberia similar to 15,000-20,000 y ago. Despite recent genomic approaches to reconstruct the continental evolutionary history, ...