Now showing items 51658-51677 of 92398

    • Lozoff, Betsy; Kaciroti, Niko; Walter, Tomas (AMER SOC CLINICAL NUTRITION, 2006-12)
      Background: Infants aged 6-24 mo are at high risk of iron deficiency. Numerous studies worldwide have sought to identify predictors of iron deficiency in this age group. Objective: The objectives of the study were to apply ...
    • Muñoz, Pablo; Humeres, Alexis (2012)
      Because of the intrinsic ability of iron to catalyze the formation of reactive oxygen species, it has been associated with oxidative stress and neurodegenerative diseases. However, iron deficiency (ID) also negatively ...
    • Aguirre, Pabla; Mena, Natalia; Tapia, Victoria; Arredondo, Miguel; Núñez González, Marco (2005)
      Background: Iron is necessary for neuronal function but in excess generates neurodegeneration. Although most of the components of the iron homeostasis machinery have been described in neurons, little is known about the ...
    • Aguirre, Pabla; Mena, Natalia P.; Tapia, Victoria; Arredondo Olguín, Miguel Armando; Núñez González, Marco (BIOMED CENTRAL LTD, 2005-01-24)
      Background: Iron is necessary for neuronal function but in excess generates neurodegeneration. Although most of the components of the iron homeostasis machinery have been described in neurons, little is known about the ...
    • Osorio, Héctor; Martínez, Verónica; Veloso, Felipe A.; Pedroso, Inti; Valdés, Jorge; Jedlicki Corbeaux, Eugenia; Holmes, David S.; Quatrini, Raquel (Elsevier B.V., 2008-11)
      An understanding of the physiology and metabolic complexity of microbial consortia involved in metal solubilization is a prerequisite for the rational improvement of bioleaching technologies. Among the most challenging ...
    • Muñoz, Juan Pablo; Chiong Lay, Mario; García Nannig, Lorena; Troncoso Cotal, Rodrigo; Toro, Barbra; Pedrozo Cibils, Zully; Díaz Elizondo, Jessica; Salas, Daniela; Parra Ortíz, María Valentina; Núñez González, Marco; Hidalgo Tapia, María Cecilia; Lavandero González, Sergio (ELSEVIER SCIENCE INC, 2010-02-15)
      We investigate here the role of reactive oxygen species and nitric oxide in iron-induced cardiomyocyte hypertrophy or cell death Cultured rat cardiomyocytes incubated with 20 mu M iron (added as FeCl3-Na nitrilotriacetate, ...
    • Muñoz, Pablo; Humeres, Alexis; Elgueta, Claudio; Kirkwood, Alfredo; Hidalgo Tapia, María Cecilia; Núñez González, Marco (AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2011-04-15)
      Iron deficiency hinders hippocampus-dependent learning processes and impairs cognitive performance, but current knowledge on the molecular mechanisms underlying the unique role of iron in neuronal function is sparse. Here, ...
    • Gómez, Francisco; Aguirre, Pabla; González Billault, Christian; Núñez González, Marco (Springer, 2011)
      Studies in post-mortem tissues of patients with Parkinson’s disease (PD) and in mice treated with 6-hydroxydopamine have shown a decrease in the length of axon and dendrites of striatal neurons. However, the etiology of ...
    • Gómez, Francisco J.; Aguirre, Pabla; González Billault, Christian; Núñez González, Marco (2011)
      Studies in post-mortem tissues of patients with Parkinson's disease (PD) and in mice treated with 6-hydroxydopamine have shown a decrease in the length of axon and dendrites of striatal neurons. However, the etiology of ...
    • Urrutia Vargas, Pamela Joselyn; Bórquez, Daniel; Núñez González, Marco (Springer, 2022)
      Iron plays essential roles in the early development of cognitive processes and in the maintenance of neuronal functions in the mature brain; therefore, neurons have expeditious mechanisms to ensure a readily available iron ...
    • Hertrampf,; Olivares,; Letelier, Carolina; Castillo, Andrea (1994)
      The frequency of anemia and iron nutrition deficiency was assessed in 342 low socioeconomic level pregnant teenagers at entry to prenatal care in 5 outpatient clinics from a South Orient area of Santiago Chile. According ...
    • Alvarado Díaz, Carlos Patricio; Núñez González, Marco; Devoto, Luigi; González Ramos, Reinaldo (Elsevier, 2015)
      Objective: To evaluate the effect of iron overload on nuclear factor kappa-B (NF-kappa B) activation in human endometrial stromal cells (ESCs). Design: Experimental study. Setting: University hospital research ...
    • Núñez González, Marco; Urrutia, P. J.; Aguirre, P.; Tapia, V.; Carrasco, C. M.; Mena, N. P. (Wiley, 2017)
    • Brito, Alex; Hertrampf, Eva; Olivares Grohnert, Manuel (The United Nations University, 2013)
      Background. The Chilean Ministry of Health has combated iron deficiency through the delivery of fortified milk by the National Complementary Feeding Program (NCFP). Objective. To assess iron status and associations between ...
    • Lozoff, Betsy; Castillo, Marcela; Clark, Katy M.; Smith, Julia B.; Sturza, Julie (ASN, 2014)
      Most studies of behavioral/developmental effects of iron deficiency anemia (IDA) or iron supplementation in infancy have found social-emotional differences. Differences could relate to behavioral inhibition or lack of ...
    • Núñez González, Marco; Tapia, Victoria; Rojas, Alejandro; Aguirre, Pabla; Gómez, Francisco; Nualart, Francisco (2010)
      00168.2009.—Intestinal iron absorption comprises the coordinated activity of the influx transporter divalent metal transporter 1 (DMT1) and the efflux transporter ferroportin (FPN). In this work, we studied the movement ...
    • Núñez González, Marco; Urrutia, Pamela J.; Mena, Natalia; Aguirre, Pabla; Tapia, Victoria; Salazar, Julio (2012)
      Iron is an essential element for life on earth, participating in a plethora of cellular processes where one-electron transfer reactions are required. Its essentiality, coupled to its scarcity in aqueous oxidative environments, ...
    • Campos, M. M.V.; Diaz, C. V.; Figueroa, K.; Padilla, L. C.; Lara H., N.; Diaz, G. F. (1994)
      Infrared spectra in the region 4000-70 cm-1 are recorded for [1,2-bis(diphenylphosphino)methane](triphenylphosphite)bromo (cis,cis- and trans-dicarbonyl)manganese, and η5-cyclopentadienyl-[1,2-bis(diphenylphosphino)ethan ...
    • Walter, Tomás; Olivares, Manuel; Pizarro Aguirre, Fernando; Muñoz, Carlos (1997)
      The data on the relationship between iron deficiency and infection are conflicting. Some researchers conclude that mild iron deficiency is beneficial for immunity, whereas others contend that any deficit is not good for ...
    • Espinoza, Alejandra; Le Blanc, Solange; Olivares, Manuel; Pizarro Aguirre, Fernando; Ruz, Manuel; Arredondo, Miguel (2012)
      Iron (Fe), copper (Cu), and zinc (Zn) fulfill various essential biological functions and are vital for all living organisms. They play important roles in oxygen transport, cell growth and differentiation, neurotransmitter ...