Browsing by Author "Núñez Vergara, Luis"
Now showing items 61-80 of 106
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(1997)A series of nitro aryl 1,4-dihydropyridine derivatives produced inhibition of both cell growth and oxygen consumption on Tulahuen and LQ strains, and clone Dm 28c of epimastigotes of Trypanosoma cruzi. Nicardipine was found ...
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(1993)Voltammetric studies of nimodipine using a mixed aqueous dimethylformamide (DMF) solvent have allowed us to generate the one-electron reduction product, the nitro radical anion RNO2 .. The cyclic voltammetry technique has ...
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(VCH Publishers. Inc., 1994)The cyclic voltammetric characteristics of two nitroamphetamine derivatives (2-nitro-4,5dimethoxyamphetamine and 2-nitro-4,5-methylenedioxyamphetamine) have been investigated in different media. In mixed media (aqueous ...
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(1994)The cyclic voltammetric characteristics of two nitroamphetamine derivatives (2‐nitro‐4,5‐dimethoxyamphetamine and 2‐nitro‐4,5‐methylenedioxyamphetamine) have been investigated in different media. In mixed media (aqueous ...
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(Elsevier, 2014)Rationale: Dihydropyridines are widely used for the treatment of several cardiac diseases due to their blocking activity on L-type Ca2+ channels and their renowned antioxidant properties. Methods: We synthesized six novel ...
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(Sociedade Brasileira de Química, 2010)Substituted chromenos, dihydropyridines and pyridines have been important in the syntheses of compounds having interesting pharmacological properties. Therefore, we found of interest to synthesize chromenopyridines and ...
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(PERGAMON-ELSEVIER SCIENCE, 2007-06-15)This work reports the electrochemical oxidation of three newly synthesized C4-hydroxyphenyl-substituted 1,4-dihydropyridine derivatives in dimethylsulfoxide. The reactivity of the compounds with ABAP-derived alkylperoxyl ...
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(1988)1. 1. Intestinal clearances of flucloxacillin significantly decrease with the increase of pH, concomitantly with a decrease of the percent absorbed at 60 min. 2. 2. The apparent rate constants for unionized (Ku) and ionized ...
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(1995)This article critically reviews the recent specialized literature concerning the influence of the stereochemical nature of quiral drugs on the pharmacokinetic processes and its pharmacological implications. Evidence is ...
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(1994)The photodecomposition of new 1,4‐dihydropyridine, furnidipine (CRE‐319); 2,6‐dimethyl‐4‐(2‐nitrophenyl)‐1,4‐dihydropy‐ridine‐3,5‐dicarboxylic acid 3‐tetrahydrofurfuryl (5‐methyl diester) was studied by voltammetric, UV‐vis ...
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(1988)The enthalpies of the reaction between glutathione and amoxycillin have been measured directly using a flow microcalorimeter. Comparative results are obtained by using an ac polarographic method previously developed in our ...
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(1978)Cephalexin was found to be polarographically reducible after hydrolysis in an acidic medium, producing two polarographic waves. Both waves were diffusion controlled. The concentration‐diffusion plot method was used for the ...
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(1988)The enthalpies of the reaction between glutathione and amoxycillin have been measured directly using a flow microcalorimeter. Comparative results are obtained by using an ac polarographic method previously developed in our ...
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(INST ORGANIC CHEM AND BIOCHEM, ACAD SCI CZECH REPUBLIC, 1991-12)Five N-p-phenyl substituted benzamidines were studied by DC and DP polarography in a wide pH range. Coulometric results show that the overall processes are four-electron reductions. Logarithmic analysis of the waves indicate ...
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(1980)
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(1979)A new polarographic method is used for quantitative analysis of ampicillin dosage forms. The electroactive product is formed by acidic hydrolysis of ampicillin. It gives a well-developed reduction wave with half-wave ...
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(Elsevier B.V., 1996)Loratadine, a potent antihistamine drug, is not directly electroreducible at a dropping mercury electrode; however, by means of a nitration procedure it is possible to obtain a nitro-loratadine derivative which has been ...
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(1992)Nimodipine, a calcium antagonist belonging to the dihydropyridine family, produces a well‐defined polarographic peak due to the four‐electron reduction of the nitro group. This peak was used to track the photodecomposition ...
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(1990)The exposure of drugs to light produces photodecomposition processes in several cases: the drugs undergo important chemical changes with a parallel change in their activities or potencies and generally with a loss of their ...
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(1990)The exposure of drugs to light produces photodecomposition processes in several cases: the drugs undergo important chemical changes with a parallel change in their activities or potencies and generally with a loss of their ...
