Browsing by Author "Cassels Niven, Bruce"
Now showing items 21-40 of 318
-
Osorio-Olivares, Mauricio; Cassels Niven, Bruce; Sepúlveda-Boza, Silvia; Rezende, Marcos Caroli (Marcel Dekker Inc., 1999)A novel route to 5,7-dimethoxy-6-hydroxyflavone is described, involving the cyclization of an intermediate phosphorane as the key step.
-
Madrero, Y.; Elorriaga, M.; Martínez, S.; Noguera, M. A.; Cassels Niven, Bruce; D'Ocon, P.; Ivorra, M. D. (Stockton Press, 1996-09-09)1 The selectivity of action of boldine and the related aporphine alkaloids, predicentrine (9-0- methylboldine) and glaucine (2,9-0-dimethylboldine) on oel-adrenoceptor subtypes was studied by examining [3H]-prazosin ...
-
Madrero, Y.; Elorriaga, M.; Martínez, S.; Noguera, M. A.; Cassels Niven, Bruce; D'Ocon, P.; Ivorra, M. D. (Stockton Press, 1996-09-19)1 The selectivity of action of boldine and the related aporphine alkaloids, predicen trine (9-0methylboldine) and glaucine (2,9-0-dimethylboldine) on (X¡-adrenoceptor subtypes was studied by examining pH]-prazosin ...
-
Madrero, Y.; Elorriaga, M.; Martinez, S.; Noguera, M. A.; Cassels Niven, Bruce; D'Ocon, P.; Ivorra, M. D. (John Wiley and Sons Inc., 1996)1 The selectivity of action of boldine and the related aporphine alkaloids, predicentrine (9-O-methylboldine) and glaucine (2,9-O-dimethylboldine) on α1-adrenoceptor subtypes was studied by examining [3H]-prazosin competition ...
-
Gómez Jeria, Juan; Cassels Niven, Bruce; Saavedra Aguilar, Juan Carlos (Elsevier Science, 1987-06-05)The electronic structure of 1-(2,5-dimethoxy-4-nitrophenyl)-2-aminopropane (DON) was calculated at the CND0/2 level, and the racemic compound was synthesized and found to be hallucinogenic at doses of 4 mg. DON differs ...
-
Gómez Jeria, Juan; Cassels Niven, Bruce; Saavedra Aguilar, Juan Carlos (1987)The electronic structure of 1-(2,5-dimethoxy-4-nitrophenyl)-2-aminopropane (DON) was calculated at the CNDO/2 level, and the racemic compound was synthesized and found to be hallucinogenic at doses of 4 mg. DON differs ...
-
Cassels Niven, Bruce; Gómez Jeria, Juan (Haight Ashbury Publications, 1985)
-
García Beltrán, Olimpo; Mena, Natalia; Berríos, Tania A.; Castro, Enrique A.; Cassels Niven, Bruce; Núñez González, Marco; Aliaga, Margarita E. (2012)In this Letter we present a new probe, 2-amino-3-hydroxy-2-(hydroxymethyl) propyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate (PMR), which can reversibly detect mercuric ions (Hg 2+) in HEPES buffer under physiological ...
-
Osorio Olivares, Mauricio; Caroli Rezende, Marcos; Sepúlveda Boza, Silvia; Cassels Niven, Bruce; Baggio, Ricardo; Muñoz Acevedo, Juan Carlos (Elsevier Science Ltd., 2003-03-12)Abstract—A simple method for the preparation of homochiral ring-substituted 1-aryl-2-aminopropanones 2 (‘cathinones’) is described, involving initial Friedel–Crafts acylation of aromatics with (S)- or (R)-N-trifluoroacetylalanyl ...
-
Torres, Milton A.; Rezendé, Marcos C.; Cassels Niven, Bruce (EIsevier Science Inc., 1997-10-03)1. Ten racemic ~-alkoxy-~-phenylethylamines were found to elicit concentrationdependent contraction of the isolated rat thoracic aorta with apparent pD2 values in the 4.56-6.76 range. With one exception, which produces ...
-
Cassels Niven, Bruce; Sepúlveda Boza, Silvia (Sociedad Chilena de Química, 1990-04-16)La bromación del 2,5-dimetoxibenzaldehído en ácido acético dió 4-bromo2,5- dimetoxi-y 2-bromo-3,6-dimetoxibenzaldehído en una razón de 4:1. El primero de éstos sufrió sustituciones nucleofilicas con tioles en DMF ...
-
Backhouse Erazo, Nadine; Delporte Vergara, Carla; Negrete Córdova, Rosa; Erazo, Silvia; Zúñiga, A.; Pinto, A.; Cassels Niven, Bruce (ELSEVIER SCI IRELAND LTD, 2001-11)The antiinflammatory and antipyretic activities of the petroleum ether extract (PEE), dichloromethane extract (DME) and methanol extract (ME1) of the aerial part of Psoralea glandulosa L. (Papilionaceae) were studied. The ...
-
Valiente, M.; D'Ocon, P.; Noguera, M. A.; Cassels Niven, Bruce; Lugnier, C.; Ivorra, N. D. (Georg Thieme, 2004-03-14)We have studied the mechanism of action of three 6a( R)-1,2-methylenedioxyaporphines as vasorelaxant compounds. The alkaloids assayed showed different affinities for the three human cloned alpha (1)-adrenoceptor (AR) ...
-
Houlihan, Lee M.; Slater, Yvonne; Guerra, Doris L.; Peng, Jian-Hong; Kuo, Yen-Ping; Lukas, Ronald J.; Cassels Niven, Bruce; Bermúdez, Isabel (International Society for Neurochemistry,, 2001-06-06)Effects of cytisine (cy), 3-bromocytisine (3-Br-cy), 5-bromocytisine (5-Br-cy) and 3,5-dibromocytisine (3,5-diBr-cy) on human (h) a7-, a4b2- and a4b4 nicotinic acetylcholine (nACh) receptors, expressed in Xenopus oocytes ...
-
Houlihan, Lee M.; Slater, Yvonne; Guerra, Doris L.; Peng, Jian Hong; Kuo, Yen Ping; Lukas, Ronald J.; Cassels Niven, Bruce; Bermudez, Isabel (2001)Effects of cytisine (cy), 3-bromocytisine (3-Br-cy), 5-bromocytisine (5-Br-cy) and 3,5-dibromocytisine (3,5-diBr-cy) on human (h) α7-, α4β2- and α4β4 nicotinic acetylcholine (nACh) receptors, expressed in Xenopus oocytes ...
-
Urzúa, Alejandro; Cassels Niven, Bruce (Pergamon Press Ltd., 1981-07-22)Asimilobine. anonaine. noreorydine. nornantenine. (+)-reticuline and lhe new alkaloid. 4-hydroxyanonaine. were isolaled from Laur~litJpllilippialla bark. The biogenelically relaled obovanine. oxopulerine and (-)-romneine. ...
-
Morales, R.; Urzúa, A.; Cassels Niven, Bruce (Universidad de Santiago de Chile, Direccion de Planificacion y Desarrollo II, 1974)De hojas y tallos de Solanum tomatillo recolectado en diciembre de 1971 en los faldeos del cerro Lo Curro (Santiago), fue aislada una sapogenina esteroidal caracterizada como diosgenina, con un rendimiento de O,002rPlo. ...
-
Sepúlveda Boza, Silvia; Cassels Niven, Bruce (Laboratorios Mixim, S.A., 1979)SOJlhork'".ide .,..1 \-al.led In 2,3~ yi.ld 'rom IlI&Vft 01 SclliIJIIS I.,jfoUlIs (An.c.rdl.c •• e), used u a lolk ~unlr.~épliv,. Thi. compoulld mi)' be relpon.lblc '01 Ihe plent', .ttrlhuted llltif,nill1y pmpel1lí1,
-
Rasamisafy, Sabina; Hocquemiller, Reynald; Cassels Niven, Bruce; Cave, Andr (American Chemical Society, 1987-02-09)
-
Negrete Córdova, Rosa; Backhouse Erazo, Nadine; Cassels Niven, Bruce (Universidad de Santiago de Chile. Dirección de Investigaciones Científicas y Tecnológicas, 1981)El alcaloide principal de las hojas de Sophora macrocarpa Sm. es la matrina. También fueron aisladas e identificadas N-metilcitisina y citisina, asi como N-óxido de matrina y el soforanol (5α -hidroximatrina). Los ...