ADDITIONAL ALKALOIDS FROM LAURELIA PHILIPPIANA AND L. NOVAE-ZELANDIAE

Abstract

Asimilobine. anonaine. noreorydine. nornantenine. (+)-reticuline and lhe new alkaloid. 4-hydroxyanonaine. were isolaled from Laur~litJpllilippialla bark. The biogenelically relaled obovanine. oxopulerine and (-)-romneine. not known as a natural produel. were oblained from lhe bark of L. lIol'a~-ulalldia~. The oeeurrenee of (R)-norlaudanosoline-derived alkaloids in L lIova~·ulallditJ~ is a distinctive feature of this tree. Neither L. not'at-ulalldiat nor L. pllilippiana aeeumulate dimeric benzylisoquinoline alkaloids lo any appreciable extenl in lhe lrunk bark. dilfering in this respeel from L. umptn·irtlls. the only other Laurtlia speeies.