Now showing items 1-20 of 4852

    • Manríquez Castro, Víctor; Labbé, Cecilia; Castillo, Mariano; Wittke Günther, Oscar (MUNKSGAARD INT PUBL LTD., 1997-05-15)
      The structure of the title diterpene, C20H34O3 (8 alpha,13R-epoxylabd-14-ene-1 alpha,5 alpha-diol), exhibits a very uncommon oxidation pattern, with two axially disposed hydroxyl substituents at C1 and C5, and five tertiary ...
    • Bravo, Héctor R.; Copaja, Sylvia V.; Figueroa-Duarte, Sebastián; Lamborot, Madeleine; San Martín, Joxsé (Verlag der Zeitschrift fur Naturforschung, 2005)
      Secondary metabolites, DIBOA, HBOA, 7-OH-HBOA, BOA and gallic acid, were isolated and quantified from Calceolaria thyrsiflora Graham, a native medicinal plant of Chile belonging to the Scrophulariaceae family. The highest ...
    • Reyes Parada, Miguel; Scorza, Cecilia; Romero, Verónica; Silveira, Rodolfo; Medina, Jorge H.; Andrus, Danice; Nichols, David E.; Cassels Niven, Bruce (Springer, 1996-05-28)
      Serotonergic behavioral responses, efTects on motor activity and core temperature, and binding properties of the novel putative anxiolytic amphe!amine derivative (± )1-(2,5-dimethoxy-4-ethylthlophenyl)- 2-aminopropane ...
    • Reyes Parada, Miguel; Scorza, Cecilia; Romero, Veronica; Silveira, Rodolfo; Medina, Jorge H.; Andrus, Danice; Nichols, David E.; Cassels Niven, Bruce (Springer Verlag, 1996)
      Serotonergic behavioral responses, effects on motor activity and core temperature, and binding properties of the novel putative anxiolytic amphetamine derivative (±)1-(2,5-dimethoxy-4-ethylthiophenyl)-2-aminopropane ...
    • Iturriaga-Vásquez, Patricio; Zapata-Torres, Gerald; Rezende, Marcos Caroli; Cassels Niven, Bruce (2004)
      The conformational preferences of a series of 1-benzyl-1,2,3,4- tetrahydroisoquinolines (norlaudanosine and coclaurine analogues) were investigated with the aid of their 1H NMR spectra and NOESY experiments, coupled with ...
    • Iturriaga-Vásquez, Patricio; Zapata Torres, Gerald Amilcar; Caroli Rezende, Marcos; Cassels Niven, Bruce (SOCIEDAD CHILENA DE QUIMICA, 2004-03)
      The conformational preferences of a series of 1-benzyl-1,2,3,4-tetrahydroisoquinolines (norlaudanosine and coclaurine analogues) were investigated with the aid of their H-1 NMR spectra and NOESY experiments, coupled with ...
    • San Martín Barrientos, Aurelio; Astudillo, Luis; Gutiérrez, Margarita; Chamy, María Cristina; Orejarena, Silvia; Rivera Latorre, Augusto; Vergara, Karen (2010)
      In addition to the known diterpenes, desoxyarticulin and dihydrotucumanoic acid, a new neoclerodane diterpene was isolated from Baccharis marginalis. The structures of the compounds were elucidated by spectroscopic evidence.
    • Jara Vergara, Paul; Yutronic Sáez, Nicolás; González Moraga, Guillermo (Taylor and Francis, 1998)
      13C CP-MAS NMR spectra of thiourea host-guest inclusion compounds containing amines, 1-azabicyclo[2.2.2]octane, 1,4-diazabicyclo[2.2.2]octane, 3-azabicyclo[3.2.2]nonane and 1, 3, 5, 7 tetrazadamantane at 25°C are reported. ...
    • Zapata-Torres, Gerald; Parra-Mouchet, Julia; Cassels Niven, Bruce (1998)
      The conformational properties of ten ring-methylated N-methyl- and N,N-dimethylanilines have been studied using 13C-NMR chemical shifts and spin-lattice relaxation times in CDCl3, and semi-empirical (AM1) quantum-chemical ...
    • Zapata Torres, Gerald Amilcar; Parra Mouchet, Julia; Cassels Niven, Bruce (Socieda Chilena de Quìmica, 1997-08-01)
      The conformational properties of ten ring-methylated N-methyl- and N,Ndimethylanilines have been studied using 13C-NMR chemical shifts and spin-Iattice relaxation times in CDCI3, and semi-empírical (AM1) quantum-chemical ...
    • Tadic, Dragana; Cassels Niven, Bruce; Laprévote, Olivier; Cavé, André (American Chemical Society, 1988-09-22)
      The 13C-nmr chemical shifts of onychine (l-methyl4-aza8uoren-9-one) [l] were assigned with the aid ofheternnuclear 2D-nmr spectraand these results were used to interpret the 13C nmr spectra of several other synthetic duorenones.
    • Morales, Raúl G.E.; Leiva, Manuel A. (Marcel Dekker Inc., 1997)
      Para-benzylideneacetones present a characteristic long distance charge transfer pattern, where the olefinic bridge (CH=CH) and the aromatic ring (Ph) carbon centers are perturbed according to the nature of the para-substituent ...
    • Morales, Raúl G.E.; Araneda, Carmen; Jara, Gregorio P.; Leiva, Manuel A. (Marcel Dekker Inc., 2000)
      By means of 13C-NMR spectroscopy and AM1 molecular orbital calculations of mono-, bi- and tri-methoxy-β-nitrostyrenes at the meta and para positions, we have characterized a long distance electronic charge transfer pattern ...
    • Araya, Carmen G.; Vargas, Víctor; Morales, Raúl G.E. (2005)
      Indoline-2-thione (BC), benzimidazole-2-thione (BN), benzoxazole-2-thione (BO), and benzothiazole-2-thione (BS) define an interesting series of aromatic compounds containing a NCS synthonic unit in a heterocyclic ring of ...
    • Lühr-Sierra, Susan; Vilches-Herrera, Marcelo; Fierro, Angélica; Ramsay, Rona; Edmondson, Dale E.; Reyes Parada, Miguel; Cassels Niven, Bruce; Iturriaga-Vásquez, Patricio (ELSEVIER, 2010)
      2-Arylthiomorpholine and 2-arylthiomorpholin-5-one derivatives, designed as rigid and/or non-basic phenylethylamine analogues, were evaluated as rat and human monoamine oxidase inhibitors. Molecular docking provided ...
    • Lühr, Susan; Vilches Herrera, Marcelo; Fierro, Angélica; Ramsay, Rona R.; Edmondson, Dale E.; Reyes Parada, Miguel; Cassels Niven, Bruce; Iturriaga-Vásquez, Patricio (2010)
      2-Arylthiomorpholine and 2-arylthiomorpholin-5-one derivatives, designed as rigid and/or non-basic phenylethylamine analogues, were evaluated as rat and human monoamine oxidase inhibitors. Molecular docking provided insight ...
    • Faini, Francesca; Torres, René; Castillo, Mariano (1984)
      (25R)-Isonuatigenin, a 5-spirosten-3β,25-diol, was isolated from aerial parts of Vestia lycioides. Its structure was elucidated mainly by 1H NMR and 13C NMR spectroscopy. A mixture of (25R)-nuatigenin and (25S)-isonuatigenin ...
    • Figueroa, Luis; Jiménez, Carlos; Rodríguez, Jaime; Areche Medina, Carlos; Chávez, Renato; Henríquez, Marlene; Cruz, Mercedes de la; Díaz, Caridad; Segade, Yuri; Vaca Cerezo, Inmaculada (Amer Chemical Soc, 2015)
      Four new nitroasterric acid derivatives, pseudogymnoascins A-C (1-3) and 3-nitroasterric acid (4), along with the two known compounds, questin and pyriculamide, were obtained from the cultures of a Pseudogymnoascus sp. ...
    • Nova Martínez, Esteban; Montecinos, Felipe; Brunet, Juan E.; Lagos Mónaco, Rosalba; Monasterio Opazo, Octavio (ELSEVIER SCIENCE INC, 2007-09-15)
      FtsZ (Filamentous temperature sensitivity Z) cell division protein from Escherichia coli binds the fluorescence probe DAPI. Bundling of FtsZ was facilitated in the presence of DAPI, and the polymers in solution remained ...
    • Villalobos, Claudio A.; Bull, Paulina; Sáez, Patricio; Cassels Niven, Bruce; Huidobro-Toro, J. Pablo (2004)
      1 We recently described that several 2-(2,5-dimethoxy-4-substituted phenyl)ethylamines (PEAs), including 4-I = 2C-I, 4-Br = 2C-B, and 4-CH 3 = 2C-D analogs, are partial agonists at 5-HT 2C receptors, and show low or even ...