Browsing by Author "201-0432762"

Now showing items 41-49 of 49

    • The role of interleukin-6 signalling and its therapeutic blockage in skewing the T cell balance in rheumatoid ... 
      Schinnerling, Katina; Aguillón Gutiérrez, Juan Carlos; Catalán Martina, Diego; Soto Sáez, Lilian (Wiley, 2017)
      Therapeutic blockage of cytokine signalling in autoimmune diseases has improved our understanding of the role of these cytokines in triggering, shaping and perpetuating autoimmune responses. In rheumatoid arthritis (RA), ...
    • The role of regulatory T lymphocytes in the induced immune response mediated by biological vaccines 
      López, Mercedes; Aguilera, Raquel; Pérez Núñez, Claudio; Mendoza Naranjo, Ariadna; Pereda, Cristian; Ramirez, Marcos; Ferrada, Carlos; Aguillón Gutiérrez, Juan Carlos; Salazar Onfray, Flavio (Elsevier GmbH, 2006)
      Immunotherapy has become a novel therapeutic alternative for various kinds of tumours. Recently, we have finalized the first phase I clinical study in Chile for the treatment of advanced malignant melanoma, using dendritic ...
    • Therapeutic potential of hyporesponsive CD4(+) T cells in autoimmunity 
      Maggi, Jaxaira; Schafer, Carolina; Ubilla Olguín, Gabriela; Catalán Martina, Diego; Schinnerling, Katina; Aguillón Gutiérrez, Juan Carlos (Frontiers Media, 2015)
      The interaction between dendritic cells (DCs) and T cells is crucial on immunity or tolerance induction. In an immature or semi-mature state, DCs induce tolerance through T-cell deletion, generation of regulatory T cells, ...
    • Therapeutic potential of hyporesponsive CD4+ T cells in autoimmunity 
      Maggi, Jaxaira; Schafer, Carolina; Ubilla Olguín, Gabriela; Catalán Martina, Diego; Schinnerling, Katina; Aguillón Gutiérrez, Juan Carlos (Frontiers Media S.A., 2015)
      © 2015 Maggi, Schafer, Ubilla-Olguín, Catalán, Schinnerling and Aguillón. The interaction between dendritic cells (DCs) and T cells is crucial on immunity or tolerance induction. In an immature or semi-mature state, DCs ...
    • TIM-1 defines a human regulatory B cell population that is altered in frequency and function in systemic ... 
      Aravena, Octavio; Ferrier, Ashley; Menon, Madhvi; Mauri, Claudia; Aguillón Gutiérrez, Juan Carlos; Soto, Lilian; Catalán Martina, Diego (BioMed Central Ltd., 2017)
      © 2017 The Author(s). Background: Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by excessive production of extracellular matrix by fibroblasts on skin and internal organs. Although Th2 cells have ...
    • Tolerogenic Dendritic Cells Derived from Donors with Natural Rubber Latex Allergy Modulate Allergen-Specific ... 
      Escobar Álvarez, Alejandro; Aguirre, Adam; Guzmán Meléndez, María Antonieta; González González, Rodrigo; Catalán Martina, Diego; Acuña Castillo, Claudio; Larrondo Lillo, Milton; López Nitsche, Mercedes; Pesce Reyes, Bárbara; Rolland, Jennifer; O’Hehir, Robyn; Aguillón Gutiérrez, Juan Carlos (2014)
      Natural rubber latex (NRL; Hevea brasiliensis) allergy is an IgE-mediated reaction to latex proteins. When latex glove exposure is the main sensitizing agent, Hev b 5 is one of the major allergens. Dendritic cells (DC), ...
    • Tolerogenic dendritic cells for reprogramming of lymphocyte responses in autoimmune diseases 
      García González, Paulina; Ubilla Olguín, Gabriela; Catalán Martina, Diego; Schinnerling, Katina; Aguillón Gutiérrez, Juan Carlos (Elsevier, 2016)
      Dendritic cells (DCs) control immune responses by driving potent inflammatory actions against external and internal threats while generating tolerance to self and harmless components. This duality and their potential to ...
    • Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures ... 
      García González, Paulina; Schinnerling, Katina; Sepúlveda Gutiérrez, Alejandro; Maggi, Jaxaira; Hoyos, Lorena; Morales, Rodrigo; Mehdi, Ahmed; Nel, Hendrik; Soto Sáez, Lilian; Pesce Reyes, Bárbara; Molina Sampayo, María Carmen; Cuchacovich Turteltaub, Miguel; Larrondo Lillo, Milton; Neira, Oscar; Catalán Martina, Diego; Hilkens, Catharien M.; Thomas, Ranjeny; Verdugo Salgado, Ricardo; Aguillón Gutiérrez, Juan Carlos (Frontiers Media, 2016-10-25)
      Tolerogenic dendritic cells (TolDCs) are promising tools for therapy of autoimmune diseases, such as rheumatoid arthritis (RA). Here, we characterize monocyte-derived TolDCs from RA patients modulated with dexamethasone ...
    • Triatoma infestans Calreticulin: Gene cloning and expression of a main domain that interacts with the host ... 
      Weinberger, Katherine; Collazo, Norberto; Aguillón Gutiérrez, Juan Carlos; Molina, Mariá Carmen; Rosas, Carlos; Penã, Jaime; Pizarro, Javier; Maldonado, Ismael; Cattan Ayala, Pedro; Apt Baruch, Werner; Ferreira, Arturo (American Society of Tropical Medicine and Hygiene, 2017)
      © 2017 by The American Society of Tropical Medicine and Hygiene.Triatoma infestans is an important hematophagous vector of Chagas disease, a neglected chronic illness affecting approximately 6 million people in Latin ...