Browsing by Title
Now showing items 9142-9161 of 91534
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(Universidad de Chile, 2013)AUTOPERCEPCIÓN ESTÉTICA-FUNCIONAL DENTO MAXILO FACIAL DE ADULTOS DESDENTADOS PARCIALES INTRODUCCIÓN: El edentulismo afecta la estética de la sonrisa y la calidad de vida de las personas, ya que la satisfacción corporal ...
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(Universidad de Chile., 2014)INTRODUCCIÓN. Los pacientes contemporáneos son más informados y participativos sobre los tratamientos disponibles. Esto ha generado la necesidad de métodos de evaluación de creencias y necesidades de salud. Se ha ...
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(FASEB, 2017)© FASEB. Brain regions affected by Alzheimer disease (AD) displaywell-recognized early neuropathologic features in the endolysosomal and autophagy systems of neurons, including enlargement of endosomal compartments, ...
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(Nature, 2020)Autophagy is an evolutionarily conserved process that plays a key role in the maintenance of overall cellular health. While it has been suggested that autophagy may elicit cardioprotective and pro-survival modulating ...
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(Frontiers, 2017-05-30)Autophagy is a catabolic mechanism where intracellular material is degraded by vesicular structures called autophagolysosomes. Autophagy is necessary to maintain the normal function of the central nervous system (CNS), ...
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(Elsevier Inc., 2018)© 2018 Elsevier Inc. Non-communicable diseases (NCDs), also known as chronic diseases, are long-lasting conditions that affect millions of people around the world. Different factors contribute to their genesis and progression; ...
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(2011)The epidemic of heart failure continues apace, and development of novel therapies with clinical efficacy has lagged. Now, important insights into the molecular circuitry of cardiovascular autophagy have raised the prospect ...
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(2012)Most neurodegenerative diseases involve the accumulation of misfolded proteins in the nervous system. Impairment of protein degradation pathways such as autophagy is emerging as a consistent and transversal pathological ...
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(Frontiers Media, 2022)Autophagy is an intracellular degradation mechanism that allows recycling of organelles and macromolecules. Autophagic function increases metabolite availability modulating metabolic pathways, differentiation and cell ...
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(Elsevier, 2012)
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(American Society for Clinical Investigation, 2015)Cardiovascular disease is the leading cause of death worldwide. As such, there is great interest in identifying novel mechanisms that govern the cardiovascular response to disease-related stress. First described in failing ...
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(Elsevier, 2020)Autophagy is an evolutionarily ancient process whereby eukaryotic cells eliminate disposable or potentially dangerous cytoplasmic material, to support bioenergetic metabolism and adapt to stress. Accumulating evidence ...
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(Elsevier B.V., 2018)© 2018 Elsevier B.V. Obesity is a major current public health problem worldwide due to the severe co-morbid conditions that this disease entails. The development of obesity-related cardiometabolic disorders is in direct ...
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(Public library science, 2018)Vascular smooth muscle cells (VSMC) dedifferentiation from a contractile to a synthetic phenotype contributes to atherosclerosis. Atherosclerotic tissue has a chronic inflammatory component with high levels of tumor necrosis ...
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(Elsevier, 2014)Mutations in fused in sarcoma and/or translocated in liposarcoma (FUS, TLS or FUS) are linked to familial cases of amyotrophic lateral sclerosis (ALS). Mutant FUS selectively accumulates into discrete cytosolic structures ...
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(2011)Aminochrome, the precursor of neuromelanin, has been proposed to be involved in the neurodegeneration neuromelanincontaining dopaminergic neurons in Parkinson's disease. We aimed to study the mechanism of aminochrome-dependent ...
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(Academia Brasileira de Ciencias, 2017)© 2017, Academia Brasileira de Ciencias. All rights reserved. Prosopis juliflora is a shrub that has been used to feed animals and humans. However, a synergistic action of piperidine alkaloids has been suggested to be ...
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(2009)CK1 constitutes a protein kinase subfamily that is involved in many important physiological processes. However, there is limited knowledge about mechanisms that regulate their activity. Isoforms CK1δ and CKlε were previously ...
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(Universidad de Chile, 2023)
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(1974)We formulate the organization of living organisms through the characterization of the class of autopoietic systems to which living things belong. This general characterization is seen at work in a computer simulated model ...