Browsing by Author "Cassels Niven, Bruce"
Now showing items 1-20 of 318
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(Springer, 1996)Serotonergic behavioral responses, efTects on motor activity and core temperature, and binding properties of the novel putative anxiolytic amphe!amine derivative (± )1-(2,5-dimethoxy-4-ethylthlophenyl)- 2-aminopropane ...
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(2004)The conformational preferences of a series of 1-benzyl-1,2,3,4- tetrahydroisoquinolines (norlaudanosine and coclaurine analogues) were investigated with the aid of their 1H NMR spectra and NOESY experiments, coupled with ...
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(SOCIEDAD CHILENA DE QUIMICA, 2004-03)The conformational preferences of a series of 1-benzyl-1,2,3,4-tetrahydroisoquinolines (norlaudanosine and coclaurine analogues) were investigated with the aid of their H-1 NMR spectra and NOESY experiments, coupled with ...
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(1998)The conformational properties of ten ring-methylated N-methyl- and N,N-dimethylanilines have been studied using 13C-NMR chemical shifts and spin-lattice relaxation times in CDCl3, and semi-empirical (AM1) quantum-chemical ...
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(Socieda Chilena de Quìmica, 1997-08-01)The conformational properties of ten ring-methylated N-methyl- and N,Ndimethylanilines have been studied using 13C-NMR chemical shifts and spin-Iattice relaxation times in CDCI3, and semi-empírical (AM1) quantum-chemical ...
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(American Chemical Society, 1988-09-22)The 13C-nmr chemical shifts of onychine (l-methyl4-aza8uoren-9-one) [l] were assigned with the aid ofheternnuclear 2D-nmr spectraand these results were used to interpret the 13C nmr spectra of several other synthetic duorenones.
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(ELSEVIER, 2010)2-Arylthiomorpholine and 2-arylthiomorpholin-5-one derivatives, designed as rigid and/or non-basic phenylethylamine analogues, were evaluated as rat and human monoamine oxidase inhibitors. Molecular docking provided ...
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(2010)2-Arylthiomorpholine and 2-arylthiomorpholin-5-one derivatives, designed as rigid and/or non-basic phenylethylamine analogues, were evaluated as rat and human monoamine oxidase inhibitors. Molecular docking provided insight ...
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2-Phenylaminonaphthoquinones and related compounds: Synthesis, trypanocidal and cytotoxic activities (Elsevier, 2014)A series of new 2-aminonaphthoquinones and related compounds were synthesized and evaluated in vitro as trypanocidal and cytotoxic agents. Some tested compounds inhibited epimastigote growth and trypomastigote viability. ...
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(2004)1 We recently described that several 2-(2,5-dimethoxy-4-substituted phenyl)ethylamines (PEAs), including 4-I = 2C-I, 4-Br = 2C-B, and 4-CH 3 = 2C-D analogs, are partial agonists at 5-HT 2C receptors, and show low or even ...
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(Nature Publishing Group, 2004-02-04)1 We recently described that several 2-(2,5-dimethoxy-4-substituted phenyl)ethylamines (PEAs), including 4-I¼2C-I, 4-Br¼2C-B, and 4-CH3¼2C-D analogs, are partial agonists at 5-HT2C receptors, and show low or even negligible ...
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(EIsevier Science Ltd., 1994-04-04)4-Dimethylaminophenethylamine (DMAPEA) was characterized as an MAO substrate. This compound was unaffected by MAO-A, while its oxidation by MAO-B was linear as a function of both time and enzyme concentration, with Km = ...
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(Elsevier , Science Ltd., 1994-04-04)4-Dimethylaminophenethylamine (DMAPEA) was characterized as an MAO substrate. This compound was unaffected by MAO-A, while its oxidation by MAO-B was linear as a function of both time and enzyme concentration, with Km = ...
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(Pergamon Press Ltd., 1978-05-29)
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(Public Library of Science, 2019)© 2019 Toro-Sazo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
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(Elsevier Inc., 1996-04-13)6-Bromoflavone, obtained by bromination of flavanone, binds to central benzodiazepine receptors witb a Ki =70 nM and has a clear anxiolytic activity in mice, at 0.5 mgJkg, i.p. A survey of tbe structure/affinity ...
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(Georg Thieme, 2005-04-13)5tructure-activity analysis of 21 aporphine derivatives was performed by examining their affinities for c10ned human alA. alB and alD adrenoceptors (AR) using membranes prepared from rat -1 fibroblasts stably expressing ...
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(2005)Structure-activity analysis of 21 aporphine derivatives was performed by examining their affinities for cloned human α1A, α1B and α1D adrenoceptors (AR) using membranes prepared from rat-1 fibroblasts stably expressing ...
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(Pergamon Press Ltd., 1983-01-21)A new quinolizidine alkaloid, (+ )-9cx-hydroxymatrine, was isolated from the lea ves of Sophora macrocarpa. Its structure was determined by a combination of spectroscopic methods, among which nuclear Overhauser enhancement ...
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(1983)A new quinolizidine alkaloid, (+)-9α-hydroxymatrine, was isolated from the leaves of Sophora macrocarpa. Its structure was determined by a combination of spectroscopic methods, among which nuclear Overhauser enhancement ...
