Browsing by Author "Kemmerling Weis, Ulrike"
Now showing items 1-20 of 30
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(Public Library Science, 2021)Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and is widely distributed worldwide because of migration. In 30% of cases, after years of infection and in the absence of treatment, ...
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(AMER SOC MICROBIOLOGY, 2008)L-Buthionine (S,R)-sulfoximine (BSO) at a dose of 220 mg/kg of body weight/day showed an anti-Trypanosoma cruzi effect in infected mice, increasing their survival rate and decreasing the parasitemias and parasite burden ...
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(Elsevier, 2021)Chagas disease is the most widespread contagious tropical disease in Latin America, being an important public health problem. Treatments against this disease are still very ineffective, presenting several side effects. ...
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(Frontiers Media, 2021)Apicomplexans are a group of pathogenic protists that cause various diseases in humans and animals that cause economic losses worldwide. These unicellular eukaryotes are characterized by having a complex life cycle and the ...
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(2011)Trypanosoma cruzi, a parasitic protozoan, is the etiological agent of Chagas disease, an endemic and neglected pathology in Latin America. It presents a life cycle that involves a hematophagous insect and man as well as ...
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(Spandidos Publ, 2015)Oral squamous cell carcinoma (OSCC) is the most common form of head and neck cancer, and oxidative damage is associated with the development of OSCCs. Antioxidants have therefore been proposed for use as chemoprotective ...
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(Public Library Science, 2018)Trypanosoma cruzi is exposed during its life to exogenous and endogenous oxidative stress, leading to damage of several macromolecules such as DNA. There are many DNA repair pathways in the nucleus and mitochondria ...
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(Universidad de Chile, 2023)La tripanosomiasis americana o enfermedad de Chagas, provocada por Trypanosoma cruzi (T. cruzi), presenta un problema de salud pública en América Latina, abarcando alrededor de veintiún países. El proceso de globalización ...
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(Universidad de Chile, 2022)La enfermedad de Chagas o Tripanosomiasis americana es causada por el parásito protozoario Trypanosoma cruzi afectando aproximadamente a 18 millones de personas en todo el mundo, generando un problema importante de salud ...
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(Universidad de Chile, 2020)La mitocondria juega un rol fundamental en la oncogénsis y en la resistencia a la quimioterapia; además se considera como un blanco terapéutico prometedor en la búsqueda de nuevos tratamientos contra el cáncer. Resultados ...
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(Universidad de Chile, 2014)La enfermedad de Chagas es causada por el parásito Trypanosoma cruzi y constituye un problema de Salud Pública cada vez más relevante en el mundo. Actualmente, las drogas antichagásicas disponibles presentan severos efectos ...
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(MDPI, 2022)Congenital Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is responsible for 22.5% of new cases each year. However, placental transmission occurs in only 5% of infected mothers and it has been proposed ...
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(John Wiley & Sons, 2014)Trypanosoma cruzi is the etiological agent of Chagas disease. The parasite has to overcome oxidative damage by ROS/RNS all along its life cycle to survive and to establish a chronic infection. We propose that T. cruzi is ...
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(2010)Mesocestodes corti has the capacity to develop from the tetrathyridium (larva) stage to adult worm in vitro by trypsin and serum stimulation. Consequently, it has been used as an experimental model system for studying ...
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(Royal Society, 2022)MicroRNAs (miRNAs) are a group of small non-coding RNAs present in a wide diversity of organisms. MiRNAs regulate gene expression at a post-transcriptional level through their interaction with the 3 ' untranslated regions ...
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(Elsevier, 2016)Benznidazole is the first-line drug used in treating Chagas disease, which is caused by the parasite Trypanosoma cruzi (T. cruzi). However, benznidazole has limited efficacy and several adverse reactions. Pentamidine is ...
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(PLoS, 2013)Chagas’ disease, produced by Trypanosoma cruzi, affects more than 8 million people, producing approximately 10,000 deaths each year in Latin America. Migration of people from endemic regions to developed countries has ...
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(Universidad de Chile, 2023)La enfermedad de Chagas es causada por el protozoo Trypanosoma cruzi y es endémica en Latinoamérica. La transmisión congénita de T. cruzi es epidemiológicamente relevante, aunque se reportan bajas tasas. Para que la ...
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(Universidad de Chile, 2022)Trypanosoma cruzi es el agente causal de la enfermedad de Chagas, la que puede ser transmitida en forma congénita. Interesantemente, sólo un porcentaje menor de las madres infectadas transmiten el parásito a sus fetos, ...
