Browsing by Author "Rodrigo Salinas, Ramón"
Now showing items 1-20 of 26
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Guajardo Beroíza, José Manuel (Universidad de Chile, 2016)Introducción: La salud corneal es esencial en el desempeño de la visión humana y la película lagrimal es un elemento central en esta función. Alteraciones de la calidad, cantidad o distribución del fluido lagrimal ...
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Rodrigo Salinas, Ramón; Retamal, Catalina; Schupper Litvak, Denisse; Vergara Hernández, Diego; Saha, Sarmistha; Profumo, Elisabetta; Buttari, Brigitta; Saso, Luciano (MDPI, 2022)Ischemia-reperfusion myocardial damage is a paradoxical tissue injury occurring during percutaneous coronary intervention (PCI) in acute myocardial infarction (AMI) patients. Although this damage could account for up to ...
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Castillo Koch, Rodrigo; Rodrigo Salinas, Ramón; Pérez, Felipe; Cereceda, Mauricio; Asenjo, René; Zamorano, Jaime; Navarrete, Roberto; Villalabeitia, Eli; Sanz, Juan; Baeza, Cristián; Aguayo, Rubén (WILEY-BLACKWELL, 2011-04)Ischaemia reperfusion injury is a pathophysiological event that occurs after cardiac surgery with extracorporeal circulation. This clinical event has been associated with the induction of oxidative and inflammatory damage ...
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González Montero, Jaime; Chichiarelli, Silvia; Eufemi, Margherita; Altieri, Fabio; Saso, Luciano; Rodrigo Salinas, Ramón (MDPI, 2022)Cancer is a disease of high mortality, and its prevalence has increased steadily in the last few years. However, during the last decade, the development of modern chemotherapy schemes, new radiotherapy techniques, targeted ...
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Sotomayor, Camilo G.; Groothof, Dion; Vodegel, Joppe J.; Gacitúa, Tomás A.; Gomes Neto, António W.; Osté, Maryse C. J.; Pol, Robert A.; Ferreccio, Catterina; Berger, Stefan P.; Chong, Guillermo; Slart, Riemer H. J. A.; Rodrigo Salinas, Ramón; Navis, Gerjan J.; Touw, Daan J.; Bakker, Stephan J. L. (MDPI, 2020)Arsenic is toxic to many organ systems, the kidney being the most sensitive target organ. We aimed to investigate whether, in kidney transplant recipients (KTRs), the nephrotoxic exposure to arsenic could represent an ...
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Rodolfo, Armas M.; Torres, Adrián R.; Jorge, Arriagada C.; Fernando, Muñoz P.; Rodrigo Salinas, Ramón; Pedro, Crocco A. (2010)Health research oriented to solve the most relevant sanitary problems in Chile must be encouraged. In 2001, the National Health Research Fund (FONIS) was created by the National Research Council of the Ministry of Health ...
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Poblete Aro, Carlos Emilio (Universidad de Chile, 2016)Antecedentes: Durante la realización de ejercicios de fuerza, se producen especies reactivas de oxigeno (ROS) que alteran el balance redox de manera aguda, lo que induce estrés oxidativo. Sin embargo, estas ROS activan ...
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Rodrigo Salinas, Ramón; Hasson, Daniel; Prieto Domínguez, Juan; Dussaillant Nielsen, Gastón; Ramos, Cristóbal; León, Lucio; Gárate, Javier; Valls, Nicolás; Gormaz, Juan (BioMed Central, 2014)Background: Acute myocardial infarction (AMI) is the leading cause of mortality worldwide. Oxidative stress has been involved in the ischemia-reperfusion injury in AMI. It has been suggested that reperfusion accounts for ...
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Bosco Becerra, Cleofina; Parra M., Victoria; Barja Yáñez, Pilar; Rodrigo Salinas, Ramón; Fernández, V.; Suarez, M.; Muñoz, H. (2005)The presence of pro-coagulant and anti-coagulant components of the placental vascular endothelium and syncytiotrophoblast are essential for homeostasis. Vascular endothelium prevents blood clot formation in vivo by involving ...
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Modulation of cytochrome P450 activity in the kidney of rats following long-term red wine exposure Orellana, Myriam; Araya, Julia; Guajardo, Viviana; Rodrigo Salinas, Ramón (2002)Cytochrome P450 (CYP)-dependent oxidation of lauric acid, p-nitrophenol and ethanol by microsomal fractions of kidney were studied in control rats and in animals given either ethanol, red wine, or alcohol-free red wine for ...
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Orellana, Myriam; Rodrigo Salinas, Ramón; Thielemann, Lilian; Jiménez, Paula; Valdés, Elena (1998)The effect of acetone consumption on some microsomal and peroxisomal activities was studied in rat kidney and these results were compared with data from former investigations in liver. Acetone increased the microsomal ...
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Thielemann, L. E.; Rodrigo Salinas, Ramón; Oberhauser, E. W.; Rosenblut, G.; Videla Cabrera, Luis (1995)The role of regenerative processes in the protective effect of N‐acetyl‐L‐cysteine (NAC) against bromoethylamine‐induced renal papillary necrosis was assessed in rats given bromoethylamine (BEA) (1.2 mmol/kg), N‐acetylcysteine ...
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Brito, R.; Castillo, G.; González, J.; Valls, N.; Rodrigo Salinas, Ramón (Johann Ambrosius Barth Verlag Medizinverlage Heidelberg GMBH, 2015)Hypertension is a highly prevalent disease worldwide. It is known for being one of the most important risk factors for developing cardiovascular disease, including acute myocardial infarction and stroke. Therefore, during ...
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Participación del estrés oxidativo en la evolución clínica de pacientes pediátricos con sepsis Molina Cancino, Víctor Manuel (Universidad de Chile, 2014)Antecedentes: La sepsis grave con síndrome de disfunción orgánica múltiple (SDOM) constituye una causa frecuente de morbilidad y gasto de recursos en unidades de paciente crítico pediátrico (UPCP). Existe abundante ...
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Peroxisomal and microsomal fatty acid oxidation in liver of rats after chronic ethanol consumption Orellana, Myriam; Rodrigo Salinas, Ramón; Valdés, Elena (1998)1. Microsomal P450 and peroxisomal fatty acid oxidation activities were studied in liver of rats after long-term ethanol consumption. 2. Ethanol increased the microsomal lauric acid ω-hydroxylation and the aminopyrine ...
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Pizarro Martínez, Rodrigo José (Universidad de Chile, 2009)La circulación extracorpórea a permitido el nacimiento y desarrollo de la cirugía cardiaca, sin embargo durante ésta, se reproduce un modelo clínico de isquemia-reperfusión. La isquemia miocárdica, se asocia a un explosivo ...
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González Montero, Jaime Alfredo. (Universidad de Chile, 2018)Introducción: El infarto agudo de miocardio (IAM) es la primera causa de muerte en el mundo. Su terapia elección es la restauración del flujo coronario mediante angioplastía coronaria percutánea (ACP). Paradójicamente, ...
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Rodrigo Salinas, Ramón; Rivera, Gonzalo; Orellana, Myriam; Araya, Julia; Bosco Becerra, Cleofina (2002)This study evaluated the antioxidant defense system of the rat kidney following chronic exposure to red wine rich in flavonols. Both ethanol and antioxidant non-alcoholic wine components, mainly polyphenols, could contribute ...
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Carrasco Loza, Rodrigo Andrés (Universidad de Chile, 2015)Antecedentes: Las antraciclinas son una importante familia de agentes quimioterapéuticos utilizados contra diferentes tipos de neoplasias, incluyendo el cáncer de mama, sin embargo su uso está limitado por la ocurrencia ...
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Berger Ovalle, Osvaldo Héctor (Universidad de Chile, 2013)En pacientes pediátricos, la sepsis es una causa importante de morbimortalidad, con una letalidad aproximada al 10%. Dentro de la fisiopatología de la sepsis, el estrés oxidativo juega un papel importante como agente ...