Now showing items 1-3 of 3

    • Briceño Catalán, Pedro Felipe; Rivas Yáñez, Elizabeth Camila; Rosemblatt Bono, Mariana Violeta; Parra Tello, Brian Josué; Farías, Paula; Vargas, Leonardo; Simon Zegers, María Valeska; Cárdenas, César; Lladser, Álvaro; Salazar Onfray, Flavio Andrés; Elorza, Álvaro A.; Rosemblatt Silber, Mario César; Bono Merino, María Rosa; Sauma Mahaluf, Daniela Macarena (Frontiers Media, 2021)
      CD39 and CD73 are ectoenzymes that dephosphorylate ATP into its metabolites; ADP, AMP, and adenosine, and thus are considered instrumental in the development of immunosuppressive microenvironments. We have previously shown ...
    • Rosemblatt Bono, Mariana Violeta; Parra Tello, Brian Josué; Briceño Catalán, Pedro Felipe; Rivas Yáñez, Elizabeth Camila; Tucer, Suat; Saavedra Almarza, Juan Pablo; Hormann Cornejo, Pilar Leonor; Martínez, Brandon A.; Lladser, Álvaro; Rosemblatt Silber, Mario César; Cekic, Caglar; Bono Merino, María Rosa; Sauma Mahaluf, Daniela Macarena (Frontiers Media, 2021)
      Ecto-5 '-nucleotidase (CD73) is an enzyme present on the surface of tumor cells whose primary described function is the production of extracellular adenosine. Due to the immunosuppressive properties of adenosine, CD73 is ...
    • Cruz, Pablo; Ahumada Castro, Ulises Jonas; Bustos, Galdo; Molgó, Jordi; Sauma Mahaluf, Daniela Macarena; Lovy, Alenka; Cárdenas, César (MDPI, 2021)
      T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy whose chemoresistance and relapse persist as a problem despite significant advances in its chemotherapeutic treatments. Mitochondrial ...