Browsing by Subject "Heterocycles"

Now showing items 1-6 of 6

    • A convenient synthesis of benzo[g]pyrrolo[3,2-c]quinoline-6,11-diones 
      Tapia, Ricardo; López, Claudio; Morello Casté, Antonio; Maya Arango, Juan; Valderrama, Jaime (2005)
      The synthesis of a new class of angular tetracyclic quinones is described. Our strategy involves Diels-Alder reaction of pyrroloquinolinequinone 9, generated in situ from pyrroloquinoline 8, and dienes. The required ...
    • Chromenopyridines: Promising scaffolds for medicinal and biological chemistry 
      Núñez Vergara, Luis; Squella Serrano, Juan; Navarrete Encina, Patricio; Vicente-García, E.; Preciado, S.; Lavilla, R. (2011)
      Chromenopyridines constitute a structurally diverse class of compounds with a wide range of bioactivities and increasing presence in drugs. Here we analyze the scope of the synthetic methodology to access this nucleus with ...
    • Gastroprotective activity of synthetic coumarins: Role of endogenous prostaglandins, nitric oxide, non-protein ... 
      Sepulveda, Beatriz; Quispe, Cristina; Simirgiotis, Mario; Torres Benítez, Alfredo; Reyes Ortíz, Johanna; Areche Medina, Carlos (Elsevier, 2016)
      Natural or synthetic coumarins showed gastroprotective and antiulcer activity in animal models. In this study, we have synthetized twenty coumarins using classic methods to evaluate their gastroprotective effects on the ...
    • Heterocyclic curcumin derivatives of pharmacological interest: Recent progress 
      Martínez Cifuentes, Maximiliano; Weiss López, Boris; Santos, Leonardo S.; Araya Maturana, Ramiro (Bentham Science Publishers B.V., 2015)
      © 2015, Bentham Science Publishers. Curcumin, a natural yellow polyphenol, is isolated from the herb Curcuma longa L. (turmeric), a member of the ginger family. It has been extensively studied due to their multiple ...
    • Highly stereoselective and catalyst-free synthesis of annulated tetrahydropyridines by intramolecular ... 
      Lezana Tobar, Nicolás; Matus Pérez, Massiel; Galdámez Silva, Antonio; Luehr, Susan; Vilches Herrer, Marcelo (Royal Society of Chemistry, 2016)
      A microwave-assisted method for the synthesis of tetracyclic tetra-hydropyridines via an intramolecular imino-Diels-Alder reaction in water is reported. The reaction proceeds under catalyst-free conditions and shows excellent ...
    • Microwave-assisted synthesis and regioisomeric structural elucidation of novel benzimidazo[1,2d][1,4]benz ... 
      Pessoa, D.; Espinosa Bustos, Christian; Mella Raipán, Jaime A.; Canales Pacheco, Jorge; Pessoa Mahana, Hernán (ARKAT USA INC, 2009)
      The synthesis of 5H-benzimidazo [1,2-d] [1,4] benzodiazepin -6(7H)-ones 3a-e from readily available 2-(2-aminophenyl)-1H-benzo[d]imidazole derivatives 2a-e and 2-bromoacetyl bromide under microwave conditions is described. ...