A convenient synthesis of benzo[g]pyrrolo[3,2-c]quinoline-6,11-diones
A_convenient_synthesis_of_benzo_g_pyrrol.pdf (26.27Kb)Abstract
The synthesis of a new class of angular tetracyclic quinones is described. Our strategy involves Diels-Alder reaction of pyrroloquinolinequinone 9, generated in situ from pyrroloquinoline 8, and dienes. The required pyrroloquinoline 8 was prepared in four steps from commercially available compounds. All compounds were tested for trypanocidal activity in vitro against Trypanosoma cruzi epimastigotes.
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Artículo de publicación SCOPUS
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URI: https://repositorio.uchile.cl/handle/2250/158875
DOI: 10.1055/s-2005-861802
ISSN: 00397881
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Synthesis. 2005(6): 903-906.
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