Advanced Search
Now showing items 211-220 of 267
Violencia obstétrica : género y derecho
(Universidad de Chile, 2018)
La violencia hacia las mujeres es un complejo fenómeno que se sostiene en una sociedad machista que la fomenta, mantiene y normaliza. Una de sus manifestaciones más invisibilizadas es la Violencia Obstétrica, que es la sufrida por las mujeres...
Estudio farmacocinético de vancomicina en pacientes críticos con shock séptico refractario durante hemofiltración de alto volumen en una unidad de cuidados intensivos
(Universidad de Chile, 2014)
(Hemofiltración de Alto Volumen, HFAV), ha mostrado beneficios hemodinámicos en los pacientes severamente enfermos. Sin embargo, aún es incierta la dosificación de antimicrobianos durante su empleo, en especial para vancomicina, glicopéptido ampliamente utilizado...
Critically ill patients have serious pharmacokinetic changes due to pathophysiological situations related to their condition and by interventions to control the initial injury. The filtration of large volumes of blood at high speed (High Volume Hemofiltration, HVHF) has shown benefits in severely ill patients. However, it is still uncertain dosing of antimicrobials during the procedure, especially for vancomycin, glycopeptide widely used in intensive care units (ICU). This study aimed to describe the individual and population pharmacokinetics of vancomycin in critically ill patients with refractory septic shock undergoing continuous venovenous HVHF and to define appropriate dosing for these patients according to several dose simulations. Method: This was a prospective pharmacokinetic study in theICU of the Universidad Católica Clinical hospital during July 2011 to July 2012. Blood and ultrafiltrate samples were taken over one vancomycin dosing interval during 12 hours of HVHF. Samples were analysed by a developed and validated liquid chromatography–tandem mass spectrometry assay. Non-linear mixed-effects modelling was used to describe the population pharmacokinetics. Dosing simulations were used to define therapeutic vancomycin doses for different HVHF settings. Results: Nine patients were included (five male). The mean weight and SOFA score was 70 kg and 11, respectively. Mean HVHF settings were: blood flow rate, 240 mL/min; and haemofiltration exchange rate, 100 mL/kg/h. A linear two-compartment model with zero-order input adequately described the data. Mean parameter estimates were: clearance (CL),2.9 L/h; volume of distribution of central compartment (V1), 11.8 L; volume of distribution of peripheral compartment (V2), 18.0 L; and intercompartmental clearance (Q), 9.3 L/h, all of them very similar to patients with normal renal function. HVHF intensity was strongly associated with vancomycin clearance (p<0.05) and was the covariate in the final pharmacokinetic model. Simulations indicate that after a loading dose, vancomycin doses required for different HVHF intensities would be 750mgevery12 h (q12 h) for 69 mL/kg/h, 1000mg q12 h for 100 mL/kg/h and 1500mg q12 h for 123 mL/kg/h. Continuous infusion would also be a valuable administration strategy. In conclusion, variable and much higher than standard vancomycin doses are required to achieve therapeutic concentrations during different HVHF settings...
Critically ill patients have serious pharmacokinetic changes due to pathophysiological situations related to their condition and by interventions to control the initial injury. The filtration of large volumes of blood at high speed (High Volume Hemofiltration, HVHF) has shown benefits in severely ill patients. However, it is still uncertain dosing of antimicrobials during the procedure, especially for vancomycin, glycopeptide widely used in intensive care units (ICU). This study aimed to describe the individual and population pharmacokinetics of vancomycin in critically ill patients with refractory septic shock undergoing continuous venovenous HVHF and to define appropriate dosing for these patients according to several dose simulations. Method: This was a prospective pharmacokinetic study in theICU of the Universidad Católica Clinical hospital during July 2011 to July 2012. Blood and ultrafiltrate samples were taken over one vancomycin dosing interval during 12 hours of HVHF. Samples were analysed by a developed and validated liquid chromatography–tandem mass spectrometry assay. Non-linear mixed-effects modelling was used to describe the population pharmacokinetics. Dosing simulations were used to define therapeutic vancomycin doses for different HVHF settings. Results: Nine patients were included (five male). The mean weight and SOFA score was 70 kg and 11, respectively. Mean HVHF settings were: blood flow rate, 240 mL/min; and haemofiltration exchange rate, 100 mL/kg/h. A linear two-compartment model with zero-order input adequately described the data. Mean parameter estimates were: clearance (CL),2.9 L/h; volume of distribution of central compartment (V1), 11.8 L; volume of distribution of peripheral compartment (V2), 18.0 L; and intercompartmental clearance (Q), 9.3 L/h, all of them very similar to patients with normal renal function. HVHF intensity was strongly associated with vancomycin clearance (p<0.05) and was the covariate in the final pharmacokinetic model. Simulations indicate that after a loading dose, vancomycin doses required for different HVHF intensities would be 750mgevery12 h (q12 h) for 69 mL/kg/h, 1000mg q12 h for 100 mL/kg/h and 1500mg q12 h for 123 mL/kg/h. Continuous infusion would also be a valuable administration strategy. In conclusion, variable and much higher than standard vancomycin doses are required to achieve therapeutic concentrations during different HVHF settings...
“Luchar por ser quien soy” Experiencias de personas trans frente a instituciones
(Universidad de Chile, 2019)
corporales de distinto tipo en su
apariencia o funcionamiento por medios quirúrgicos y hormonales, y a la vez manifestar o
no, las conductas asociadas socialmente al género con el cual se identifican. (Principios
de Yogyakarta, 2006)
2 Los Principios...
tratamientos de salud hormonales y quirúrgicos para llevar a cabo modificaciones corporales por parte de las instituciones prestadoras de salud.(Adrián, 2013) En este sentido, de acuerdo con Adrián (2013), en el caso del DSM-5, la solución a esta disyuntiva...
tratamientos de salud hormonales y quirúrgicos para llevar a cabo modificaciones corporales por parte de las instituciones prestadoras de salud.(Adrián, 2013) En este sentido, de acuerdo con Adrián (2013), en el caso del DSM-5, la solución a esta disyuntiva...
Tratamiento fonoaudiológicos para el manejo de la sialorrea en usuarios con Enfermedad de Parkinson
(Universidad de Chile, 2012)
Este estudio propone dos tratamientos fonoaudiológicos para la sialorrea (producción de saliva que el paciente percibe como excesiva) en la Enfermedad de Parkinson (EP), uno es la Terapia Conductivo Conductual (TCC), que consiste en la...
This research proposes two phonoaudiological treatments for the Sialorrhea (salivation that the patient perceives as excessive) in Parkinson’s Disease (PD), the first is the Cognitive Conductual Therapy (CCT), that involves making the patient aware of the swallowing process. As a complement to this treatment, the Thermo-Tactile Stimulation (TTE) is used, involving the sensorial stimulation of the anterior pharyngeal pillars and oral cavity. With this, the oral sensitivity is increased. The target of this investigation is to measure whether there is a significative difference between treating with CCT against treating with it along with TTE. The surveyed population was people with diagnosed Parkinson’s Desease and Sialorrhea. For confirming the sample, 18 Chilean were selected. The subjects were divided in two groups, one treated only with CCT (A) and the other with CCT along with TTE (B), for 5 weeks. In the analysis, in order to establish whether there is a significative difference in the perception of Sialorrhea before or after the treatment in each group, the parametric T-student test will be used for related samples. Moreover, to determine if there is any difference between the perception of Sialorrhea achieved by each of the treatments, the Mann-Withney Test will be used. These tests will demonstrate how effective the treatment might be towards decreasing the perception of Sialorrhea in the subjects. Nevertheless, no statistically significative differences were shown neither using the treatment A, nor B....
This research proposes two phonoaudiological treatments for the Sialorrhea (salivation that the patient perceives as excessive) in Parkinson’s Disease (PD), the first is the Cognitive Conductual Therapy (CCT), that involves making the patient aware of the swallowing process. As a complement to this treatment, the Thermo-Tactile Stimulation (TTE) is used, involving the sensorial stimulation of the anterior pharyngeal pillars and oral cavity. With this, the oral sensitivity is increased. The target of this investigation is to measure whether there is a significative difference between treating with CCT against treating with it along with TTE. The surveyed population was people with diagnosed Parkinson’s Desease and Sialorrhea. For confirming the sample, 18 Chilean were selected. The subjects were divided in two groups, one treated only with CCT (A) and the other with CCT along with TTE (B), for 5 weeks. In the analysis, in order to establish whether there is a significative difference in the perception of Sialorrhea before or after the treatment in each group, the parametric T-student test will be used for related samples. Moreover, to determine if there is any difference between the perception of Sialorrhea achieved by each of the treatments, the Mann-Withney Test will be used. These tests will demonstrate how effective the treatment might be towards decreasing the perception of Sialorrhea in the subjects. Nevertheless, no statistically significative differences were shown neither using the treatment A, nor B....
Envejecimiento y menopausia: experiencias corporales e identidad de género en mujeres mayores de la Región Metropolitana
(Universidad de Chile, 2015)
Universidad de Chile
Facultad de Ciencias Sociales
Carrera de Antropología
Envejecimiento y Menopausia: Experiencias Corporales e Identidad de
Género en Mujeres Mayores de la Región Metropolitana...
. 3 Agradecimientos A mi papá, Sergio Navarrete, y a mi mamá, Isolda Luco, por apoyarme incondicionalmente en mi corto camino por la Antropología. A mi tía, Lorna Luco, por ser mi "hada madrina", ya que gracias a ella llegué a trabajar en...
. 3 Agradecimientos A mi papá, Sergio Navarrete, y a mi mamá, Isolda Luco, por apoyarme incondicionalmente en mi corto camino por la Antropología. A mi tía, Lorna Luco, por ser mi "hada madrina", ya que gracias a ella llegué a trabajar en...
Estudio y análisis del proceso de planificación, desarrollo y operación de concesiones hospitalarias en Chile y en el extranjero
(Universidad de Chile, 2020)
-Privadas (APP) en salud, como las denominan en otros países se definen como un contrato entre el Estado y una Sociedad de Propósito Especifico, destinado a la construcción, conservación y/o explotación de una infraestructura hospitalaria, construida sobre...
Bucalle : la clínica odontológica de la familia
(Universidad de Chile, 2018-07)
El presente informe es el Plan de Negocios de Clínica Odontológica de la Familia “Bucalle”, especialista en servicios de odontopediatría y odontología para embarazadas que busca, bajo el concepto de “prevención desde el momento de nacer”, cubrir una...
Redacción de los manuales de organización y procedimientos para el Subdepartamento de Farmacia del Hospital El Carmen Dr. Luis Valentín Ferrada
(Universidad de Chile, 2017)
trabajadas a la semana, turno, calidad contractual y ley bajo la cual se trabaja.
En la misma tabla, se hizo la diferencia entre aquellos funcionarios que pertenecen
directamente al Hospital El Carmen y los contratados por el CRS Maipú (Centro de...
Manual de Procedimientos (Protocolos Generales) .............. 7 Figura N°5. Contenido del Manual de Procedimientos (Protocolos Específicos) ............ 8 Figura N°6. Áreas presentes en el Subdepartamento de Farmacia .............................. 11...
Manual de Procedimientos (Protocolos Generales) .............. 7 Figura N°5. Contenido del Manual de Procedimientos (Protocolos Específicos) ............ 8 Figura N°6. Áreas presentes en el Subdepartamento de Farmacia .............................. 11...
Fármacos, salud y vida : las armas y metas de la farmacia
(2011)
Digitación:
Juanita Arias S.
Impreso en Impresores Salesianos
Eliodoro Yañes 1649 of 402
Este libro será distribuido gratuitamente
Prohibida su venta.
5Fármacos, Salud y Vida
“Las armas y metas de la farmacia”
6
7Los conceptos y mensajes que contiene este...
trabajo tienen por destinatarios a mis colegas de todo el país, que esforzada y generosamente entregan su aporte a la salud de la población. En especial, a los jóvenes farmacéuticos que deberán asumir la inmensa tarea de reivindicar y jerarquizar...
trabajo tienen por destinatarios a mis colegas de todo el país, que esforzada y generosamente entregan su aporte a la salud de la población. En especial, a los jóvenes farmacéuticos que deberán asumir la inmensa tarea de reivindicar y jerarquizar...
Descripción de reflejos y funciones orofaciales en un grupo de lactantes de términos y pretérmino, de 6 y 9 meses de edad corregida
(Universidad de Chile, 2012)
El desarrollo de la alimentación de los niños se sitúa dentro de un continuo, que evoluciona de los reflejos orofaciales. La adecuada evolución y ejecución de estas funciones son importantes para el desarrollo maxilofacial del menor. en los últimos...
The development of feeding children is within a continuous, evolving from orofacial reflexes into orofacial functions. The proper development and implementation of these functions are important for the maxillofacial development of the child. In recent years, an increasing number of children born prematurely. This premature condition can cause various alterations on neurodevelopment of orofacial functions, which could directly affect the acquisition of appropriate eating patterns, interfering with optimal nutrition and feeding of the child. The purpose of this seminar research is to describe and compare the reflexes and orofacial functions between term and preterm infants of 6 and 9 months corrected age without neurological damage and submit medical stability, in order to determine whether there are differences in the performance of these parameters....
The development of feeding children is within a continuous, evolving from orofacial reflexes into orofacial functions. The proper development and implementation of these functions are important for the maxillofacial development of the child. In recent years, an increasing number of children born prematurely. This premature condition can cause various alterations on neurodevelopment of orofacial functions, which could directly affect the acquisition of appropriate eating patterns, interfering with optimal nutrition and feeding of the child. The purpose of this seminar research is to describe and compare the reflexes and orofacial functions between term and preterm infants of 6 and 9 months corrected age without neurological damage and submit medical stability, in order to determine whether there are differences in the performance of these parameters....