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Artículo

Genotoxic stress triggers the activation of IRE1 alpha-dependent RNA decay to modulate the DNA damage response

Dufey, Estefanie; Bravo San Pedro, José; Eggers Aracena, Cristián; González Quiroz, Matías; Urra Zúñiga, Hery; Sagredo Campos, Alfredo; Sepúlveda Alvarado, Denisse; Pihán Najle, Philippe; Carreras Sureda, Armando; Hazari, Younis; Sagredo, Eduardo A.; Gutiérrez, Daniela; Valls, Cristian; Papaioannou, Alexandra; Acosta Alvear, Diego; Campos, Gisela; Domingos, Pedro M.; Pedeux, Rémy; Chevet, Eric; Álvarez, Alejandra R.; Godoy, Patricio; Walter, Peter; Glavic Maurer, Álvaro; Kroemer, Guido; Hetz Flores, Claudio (Nature, 2020)

Artículo

Targeting of the unfolded protein response (UPR) as therapy for Parkinson's disease

Martinez, Alexis; Lopez, Nelida; Gonzalez, Constanza; Hetz Flores, Claudio (Wiley-Blackwell Publishing Ltd, 2019)

Artículo

Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis

Beltran, S.; Nassif, M.; Vicencio, E.; Arcos, J.; Labrador, L.; Cortes, B. I.; Cortez, C.; Bergmann, C. A.; Espinoza, S.; Hernandez, M. F.; Matamala, J. M.; Bargsted, L.; Matus, S.; Rojas-Rivera, D.; Bertrand, M. J.M.; Medinas, D. B.; Hetz Flores, Claudio; Manque, P. A.; Woehlbier, U. (BioMed Central Ltd., 2019)

Artículo

TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis

Rojas Rivera, Diego; Armisen Yáñez, Ricardo; Colombo, A.; Martínez, G.; Eguiguren, A. L.; Díaz, A.; Kiviluoto, S.; Rodríguez, D.; Patron, M.; Rizzuto, R.; Bultynck, G.; Concha Nordemann, Miguel; Sierralta, J.; Stutzin Schottlander, Andrés; Hetz Flores, Claudio (2012)

Artículo

The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease

Oñate, Maritza; Catenaccio, Alejandra; Salvadores, Natalia; Saquel, Cristian; Martínez Rojas, Luis; Moreno González, Inés; Gamez, Nazaret; Soto, Paulina; Soto, Claudio; Hetz Flores, Claudio; Court, Felipe A. (Nature Publishing Group, 2020)

Artículo

Mechanisms, regulation and functions of the unfolded protein response

Hetz Flores, Claudio; Zhang, Kezhong; Kaufman, Randal J. (Nature, 2020)

Artículo

Fine-tuning ER stress signal transducers to treat amyotrophic lateral sclerosis

Medinas Bilches, Danilo; González, José V.; Falcon, Paulina; Hetz Flores, Claudio (Frontiers Media SA, 2017)

Artículo

Getting intimate: lysosomes and ER rendezvous to control autophagy

Pihán, Philippe; Hetz Flores, Claudio (Elsevier, 2020)

Artículo

Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates

García Huerta, Paula; Troncoso Escudero, Paulina; Wu, Di; Thiruvalluvan, Arun; Cisternas, Marisol; Henríquez, Daniel R.; Plate, Lars; Chana-Cuevas, Pedro; Saquel, Cristian; Thielen, Peter; Longo, Kenneth A.; Geddes, Brad J.; Lederkremer, Gerardo Z.; Sharma, Neeraj; Shenkman, Marina; Naphade, Swati; Sardi, S. Pablo; Spichiger, Carlos; Richter, Hans G.; Court, Felipe A.; Tshilenge, Kizito Tshitoko; Ellerby, Lisa M.; Wiseman, R. Luke; Gonzalez Billault, Christian; Bergink, Steven; Vidal, René L.; Hetz Flores, Claudio (Springer, 2020)

Artículo

Publisher Correction: Pharmacological targeting of the unfolded protein response for disease intervention (Nature Chemical Biology, (2019), 15, 8, (764-775), 10.1038/s41589-019-0326-2)

Hetz Flores, Claudio; Axten, Jeffrey M.; Patterson, John B. (Nature Publishing Group, 2019)

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