Now showing items 1013-1032 of 8150

    • Bustos, H.; Mantoiu, Marius Laurentiu (Univ Houston, 2016)
      We introduce covariant structures {(A, kappa), (a, alpha), ((a) over tilde, (alpha) over tilde)} formed of a separable C*-algebra A, a measurable twisted action (a, alpha) of the second-countable locally compact group G, ...
    • Khalladi M.T., Kostic M., Pinto M., Rahmani A., Velinov D. (Walter de Gruyter GmbH, 2020)
    • Abin Carriquiry, Juan Andrés; Voutilainen, Merja H.; Barik, Jacques; Cassels Niven, Bruce; Iturriaga-Vásquez, Patricio; Bermúdez, Isabel; Durand, Claudia; Dajas, Federico; Wonnacott, Susan (ELSEVIER, 2006)
      Neuronal nicotinic acetylcholine receptors subserve predominantly modulatory roles in the brain, making them attractive therapeutic targets. Natural products provide key leads in the quest for nicotinic receptor subtype-selective ...
    • Urbina, Daniela C.; Silva Ascencio, Herman; Lee A., Meisel (2006)
      Thapsigargin, a specific inhibitor of most animal intracellular SERCA-type Ca2+ pumps present in the sarcoplasmic/endoplasmic reticulum, was originally isolated from the roots of the Mediterranean plant Thapsia gargancia ...
    • González Silva, Carolina; Vera, Jorge; Bono Merino, María Rosa; González Billault, Christian; Baxter, Brooke; Hansen, Anne; López, Robert; Gibson, Emily A.; Restrepo, Diego; Bacigalupo Vicuña, Juan (PLoS ONE, 2013)
      The Ca2+-activated Cl2 channel is considered a key constituent of odor transduction. Odorant binding to a specific receptor in the cilia of olfactory sensory neurons (OSNs) triggers a cAMP cascade that mediates the opening ...
    • Soto, Marco A.; González, Carlos; Lissi Gervaso, Eduardo A.; Vergara Montecinos, Cecilia; Latorre, Ramón (AMER PHYSIOLOGICAL SOC, 2002-03)
      We studied the effect of H2O2 on the gating behavior of large-conductance Ca2+-sensitive voltage-dependent K+ (K-V,K-Ca) channels. We recorded potassium currents from single skeletal muscle channels incorporated into ...
    • Castillo, Karen; Bacigalupo Vicuña, Juan; Wolff Fernández, José (ELSEVIER SCIENCE BV, 2005-03-14)
      Olfactory cilia contain cyclic nucleotide-gated and Ca2+-dependent Cl- conductances that underlie excitatory chemotransduction, and a Ca2+-dependent K+ (K-Ca) conductance, apparently involved in inhibitory transduction. ...
    • Belmar, Carolina A.; Alfaro, Silvia; Munita, Doina; Albornoz, Ximena; Carrasco, Carolina; Echeverría, Javier; Mera, Rodrigo; Adán, Leonor; Quiroz, Luciana; Niemeyer, Hermann M.; Planella, Maria Teresa (Universidad de Magallanes, 2017)
      Archaeological and ethnohistorial data show that smoking practices in the central-southern region of Chile begins during the Early Ceramic period and continue until historical times. In view of this long time span, twelve ...
    • San Martín Rovirosa, Carol; Garri, Carolina; Pizarro Aguirre, Fernando; Walter, Tomas; Theil, Elizabeth C.; Núñez González, Marco (Journal of Nutrition, 2008-05)
      Iron deficiency, a condition currently affecting ;3 billion people, persists in the 21st century despite half a millennium of medical treatment. Soybean ferritin (SBFn), a large, stable protein nanocage around a mineral ...
    • Cortés, M.; Garbarino, J. A.; Cassels Niven, Bruce (ELSEVIER, 1971-07-30)
      Trichocereus chilensis (Colla) Br. & R. is the only Chilean member of its genus figuring in the literature as having been examined for alkaloids, although previous reports are negative. Djerassi and coworkers1 found no ...
    • Peña Leiva, Alejandro Ernesto (Universidad de Chile, 1990)
      El propósito principal de esta tesis es aportar evidencias experimentales, que ayuden a precisar los mecanismos responsables de la hipertensión, observada en aquellos individuos expuestos a cadmio, tales como aquellos que ...
    • Fajardo, Víctor; Garrido, Margarita; Cassels Niven, Bruce (ELSEVIER, 1980-10-13)
      A new bisbenzylisoquinoline alkaloid fran Berberis buxifolia was chemically correlated with ealafatine. On this basis, and using spectranetric evidence, structure 1is proposed for ealafatirnine. The stereochanistry ...
    • Fajardo, V.; Urzúa, A.; Cassels Niven, Bruce (Universidad Técnica del Estado, 1978-11)
      La calafatina es un componente importante de las mezclas de alcaloides no cuaternarios de la corteza de tronco y de las raiees de Berberis buxifolia Lam. ("calafate"). Sobre la base de estudios espectrométricos de esta ...
    • Fajardo, Víctor; Urzúa, Alejandro; Cassels Niven, Bruce (ELSEVIER, 1979-09-26)
      Spectrometric and chemical evidence is presented that calafatine, an alkaloid from Berberis buxifolia, has structure l. The substitution pattern on ring E is unique ln isoquinoline alkaloids.
    • Contreras, E.; Quijada, L.; Germany, A.; Fleckenstein, R.; Hernández, A. (1993)
      1. A single dose of pentazocine induces cross-tolerance the analgesic effects of the kappa agonist U 50488H. Tolerance is observed by means of the hot plate test or by the i.p. administration of acetic acid 6 or 24 hr after ...
    • Palma, Verónica; Kukuljan Padilla, Manuel; Mayor, Roberto (Cell Press, 2001)
      Calcium signals participate in the differentiation of electrically excitable and nonexcitable cells; one example of this differentiation is the acquisition of mature neuronal phenotypes [1]. For example, transient elevations ...
    • Schmachtenberg, O.; Bacigalupo Vicuña, Juan (2000)
      Nitric oxide (NO) activates a K+ current in dissociated amphibian olfactory receptor neurons. Using the patch-clamp technique in its whole-cell mode and stimulation with puffs of the NO-donor sodium nitroprusside, we further ...
    • Carrasco, María Angélica; Magendzo, Karin; Jaimovich Pérez, Enrique; Hidalgo Tapia, María Cecilia (1988)
      Highly purified transverse tubule membranes isolated from frog skeletal muscle phosphorylate phosphatidylinositol to phosphatidylinositol 4-phosphate and phosphatidylinositol (4,5)-bisphosphate. The two phosphorylation ...
    • Vergara Montecinos, Cecilia; Latorre, Ramón; Marrion, Neil V.; Adelman, John P. (Elsevier Ltd, 1998)
      Calcium-activated potassium channels are fundamental regulators of neuronal excitability, participating in interspike interval and spike-frequency adaptation. For large-conductance calcium-activated potassium (BK) channels, ...
    • Arratia Pérez, Ramiro; Alvarez Thon, Luis; Fuentealba Rosas, Patricio (ELSEVIER, 2004-10-21)
      All-electron spin polarized DFT calculations have been performed to optimize the pentagonal bipyramidal (D-5h) geometry of the Cu-7 cluster by using the B3LYP and the B3PW1 functionals with different basis sets. Dirac ...