Browsing by Author "Ocaranza, María Paz"

Now showing items 21-26 of 26

    • Rho kinase activation and gene expression related to vascular remodeling in normotensive rats with high ... 
      Rivera, Paulina; Ocaranza, María Paz; Lavandero González, Sergio; Jalil Milad, Jorge (LIPPINCOTT WILLIAMS & WILKINS, 2007-10)
      The RhoA/Rho kinase (ROCK) pathway is a new mechanism of remodeling and vasoconstriction. Few data are available regarding ROCK activation when angiotensin I-converting enzyme is high and blood pressure is normal. We ...
    • Rho kinase inhibition activates the homologous angiotensin-converting enzyme-angiotensin-(1-9) axis in ... 
      Ocaranza, María Paz; Rivera, Paulina; Novoa, Ulises; Pinto, Melissa; González, Leticia; Chiong Lay, Mario; Lavandero González, Sergio; Jalil Milad, Jorge (LIPPINCOTT WILLIAMS & WILKINS, 2011-04)
      Background Angiotensin II (Ang II) levels depend on renin, angiotensin-converting enzyme (ACE), and on the homologous angiotensin-converting enzyme (ACE2). Increased ACE and Ang II levels are associated with higher Rho ...
    • Rho-kinase pathway activation and apoptosis in circulating leucocytes in patients with heart failure with ... 
      Ocaranza, María Paz; Moya, Jackeline; Jalil, Jorge E.; Lavandero González, Sergio; Kalergis, Alexis M.; Molina, Cristián; Gabrielli, Luigi; Godoy, Iván; Córdova, Samuel; Castro, Pablo; Mac Nab, Paul; Rossel Mariángel, Víctor; García, Lorena; González, Javier; Mancilla, Cristián; Fierro, Camila; Farías, Luis (Wiley, 2020)
      Background: Increased Rho-kinase activity in circulating leucocytes is observed in heart failure with reduced ejection fraction (HFrEF). However, there is little information in HFrEF regarding other Rho-kinase pathway ...
    • Rho/Rho kinase signal transduction pathway in cardiovascular disease and cardiovascular remodeling. La ... 
      Jalil Milad, Jorge; Lavandero González, Sergio; Chiong Lay, Mario; Ocaranza, María Paz (EDICIONES DOYMA S/L, 2005-08)
      The small guanosine triphosphatase Rho and its target, Rho kinase, play important roles in both blood pressure regulation and vascular smooth muscle contraction. Rho is activated by agonists of receptors coupled to cell ...
    • Soluble interleukin-6 receptor regulates interleukin-6-dependent vascular remodeling in long-distance runners 
      Villar Fincheira, Paulina Fernanda; Paredes, Aaron J.; Hernández Díaz, Tomás Alonso; Norambuena Soto, Ignacio Esteban; Cancino Arenas, Nicole Ester; Sanhueza Olivares, Fernanda; Contreras Briceño, Felipe; Mandiola, Jorge; Bruneau Leyton, Nicole Nayira; García Nannig, Lorena; Ocaranza, María Paz; Troncoso Cotal, Rodrigo Hernán; Gabrielli, Luigi; Chiong Lay, Mario Martin (Frontiers Media, 2021)
      Little is known about the effects of training load on exercise-induced plasma increase of interleukin-6 (IL-6) and soluble IL-6 receptor (sIL-6R) and their relationship with vascular remodeling. We sought to evaluate the ...
    • La vía de señalización Rho/Rho-cinasa en la enfermedad y el remodelado cardiovascular 
      Jalil Milad, Jorge; Lavandero González, Sergio; Chiong Lay, Mario; Ocaranza, María Paz (Sociedad Española de Cardiología, 2005)
      La guanosina trifosfatasa pequeña Rho y su blanco Rho-cinasa desempeñan un papel importante en la regulación de la presión arterial y en la contracción de la musculatura lisa vascular. Diversos agonistas de los receptores ...