Now showing items 3228-3247 of 4844

    • Martínez Pinto, Jonathan Eloy; Piquer Franco, Beatriz Gabriela; Tiszavari, Michelle; Lara, Hugo (Elsevier INC, 2018)
      To understand the impact of exposure to steroids in the early step of ovary development(a stage occurring in uterus in humans), we studied neonatal exposure to estradiol valerate (EV) in rats regarding polycystic ovary ...
    • Romero Osses, Carmen; Paredes Vargas, Alfonso; Dissen, G. A.; Ojeda, Sergio R. (ENDOCRINE SOC, 2002-04)
      The neurotrophin nerve growth factor (NGF) and its two membrane-anchored receptors are expressed in the developing ovary before the organization of the first primordial follicles. In the absence of NGF, the growth of ...
    • Martínez Hernández, Eduardo; Hammoud, Zaynab; De Sousa, Alessandra Mara; Kramer, Frank; Do Monte-Neto, Rubens L.; Maracajá Coutinho, Vinicius; Martin, Alberto J. M. (Amer Soc Microbiology, 2021)
      Leishmania parasites are the causal agent of leishmaniasis, an endemic disease in more than 90 countries worldwide. Over the years, traditional approaches focused on the parasite when developing treatments against ...
    • Carmona-Fontaine, Carlos; Acuña, Gustavo; Ellwanger, Kristina; Niehrs, Christof; Mayor, Roberto (Academic Press Inc., 2007)
      It is known the interactions between the neural plate and epidermis generate neural crest (NC), but it is unknown why the NC develops only at the lateral border of the neural plate and not in the anterior fold. Using ...
    • Mani, Shaila K.; Anselmo-Franci, Janete; Lara Peñaloza, Hernán; Suchecki, Deborah; Poletini, Maristela O.; Handa, Robert J.; John Wu, Tao-yiao (British Society for Neuroendocrinology, 2014)
    • Ávalos, Ana María; Valdivia, A. D.; Muñoz, Nicolás; Herrera Molina, Rodrigo; Tapia Pineda, Julio; Lavandero González, Sergio; Chiong Lay, Mario; Burridge, Keith; Schneider, P.; Quest, Andrew F. G.; Leyton Campos, Lisette (COMPANY OF BIOLOGISTS LTD, 2009-10)
      Clustering of alpha v beta 3 integrin after interaction with the RGD-like integrin-binding sequence present in neuronal Thy-1 triggers formation of focal adhesions and stress fibers in astrocytes via RhoA activation. A ...
    • Dissen, G. A.; Romero Osses, Carmen; Paredes Vargas, Alfonso; Ojeda, Sergio R. (WILEY-LISS, DIV JOHN WILEY & SONS INC, 2002-12-15)
      Substantial evidence now exists indicating that the neurotrophins, a family of growth factors required for the survival, development, and differentiation of various neuronal populations of the nervous system, are also ...
    • Grau, Fanny; Bayón, J.; Aguirre, Pedro; Parella, Teodor; Duñach, Elisabet (2008)
      The Rh-catalysed hydroformylation of isopropylidenecyclohexane derivatives obtained by intramolecular diene cyclisations affords the corresponding aldehydes in good yields and in a completely chemo- and regioselective ...
    • Marini-Bettòlo, G. B.; Delle Monache, E. M.; Erazo, Silvia; Galeffi, Corrado (Societá Chimica Italiana, 1971)
      From the stem bark of Strychnos romeu-belenii Krukoff and Barneby, a Longaniacea of South America, a new indolinic alkaloid has been isolated to which the structure of 11-,11-methoxy-diaboline(I) has been assigned on the ...
    • Jachero, Lourdes; Ahumada Torres, Aída Inés de Lourdes; Fuentes Pérez, Edwar; Richter Duk, Pablo (Elsevier, 2015)
      A new biomimetic approach for triclosan (TCS) was developed based on the leaching of the analyte from different biosolid-amended agricultural soils and the subsequent extraction of the leachates, using a rotating disk ...
    • Pouche, Lucie; Stojanova, Jana; Marquet, Pierre; Picard, Nicolas (Future Medicine, 2016)
      Interindividual variability in immunosuppressive drug responses might be partly explained by genetic variants in proteins involved in the immune response or associated with IS pharmacodynamics. On a general basis, the ...
    • Parra, M.; Vergara, J.; Zúñiga, C.; Soto, E.; Sierra, T.; Serrano, J. (2005)
      Two new homologous series of chiral esters derived from Schiff's bases containing a 1,3,4-thiadiazole unit (series 6 and 7) were synthesized and their liquid crystalline and ferroelectric properties investigated. All the ...
    • Ordronneau, Lucie; Boixel, Julien; Aubert, Vincent; Vidal, Matias S.; Palma Moya, Sergio Andrés; Aguirre, Pedro; Toupet, Loic; Williams, J. A Gareth; Le Bozec, Hubert; Guerchais, Véronique (Royal Society of Chemistry, 2014)
      The synthesis and characterization of a series of fluorescent bis-dithienylethene (DTE)-based bipyridines, where the donor (D) and acceptor (A) groups are located on the same thiophene ring of the DTE unit, and their ...
    • Barriga, Germán; Olea Azar, Claudio; Norambuena, Ester; Castro, Ana; Porcal, Williams; Gerpe, Alejandra; González, Mercedes; Cerecetto, Hugo (ELSEVIER, 2010)
      A new series of heteroaryl nitrones, 1–7, bearing furoxanyl and thiadiazolyl moieties, were evaluated for their free radical-trapping properties. The physicochemical characterization by electron paramagnetic resonance ...
    • Rodríguez Arce, Esteban; Putzu, Eugenia; Lapier, Michel; Maya Arango, Juan; Olea Azar, Claudio; Echeverría, Gustavo A.; Piro, Oscar E.; Medeiros, Andrea; Sardi, Florencia; Comini, Marcelo; Risi, Gastón; Salinas, Gustavo; Correia, Isabel; Pessoa, João Costa; Otero, Lucía (Royal Society of Chemistry, 2019)
      In the search for a more effective chemotherapy for the treatment of Chagas' disease and human African trypanosomiasis, caused by Trypanosoma cruzi and Trypanosoma brucei parasites, respectively, the use of organometallic ...
    • Sobarzo Sánchez, Eduardo; Saitz Barría, Claudio; Jullian Matthaei, Carolina; Cassels Niven, Bruce (MARCEL DEKKER INC, 2002)
      The abundant aporphine alkaloid (S)-(+)-boldine (1) was selectively nitrosated with sodium nitrite in acetic acid affording 8-nitrosoboldine (2) which was hydrogenated catalytically to give 8-aminoboldine (3). The latter ...
    • Cruz, Carlos; Vega Carvallo, Andrés Igor; Spodine, Evgenia; Escuer, Albert; Marco, José F.; Menéndez, Nieves; Venegas Yazigi, Diego; Paredes García, Verónica (American Chemical Society, 2020)
      In this work, we report a new octanuclear cluster based on FeIII and the ligand 1H-imidazole-4,5-dicarboxylic acid, [Et3NH](12)[Fe-8(IDC)(12)]center dot 10DMF center dot 13H(2)O (1), with a metal core containing eight ...
    • Ramírez, Oscar; Leal, Matías; Briones Olaran, Ximena Gabriela; Urzúa Acevedo, Marcela del Pilar; Bonardd, Sebastián; Saldías, César; Leiva, Angel (MDPI, 2022)
      In this work, we report the obtaining of new hybrid nanocomposites with catalytic activity formed by nanofibers of polymer blends and gold nanoparticles. The nanofibers were obtained by electrospinning blends of a poly ...
    • Cornwell, E. (SOCIEDAD CHILENA DE QUIMICA, 2006-03)
      In QSRR discipline an easy novel to used parameter was designed (Vc) for evaluated classical topological index (W, (1)chi, Z, MTI) and two new generation ones (Xu, (1)chi(h)). Regression between Vc and (1)chi(h) presented ...
    • Troncoso Cotal, Rodrigo Hernán; Ibarra, Cristián; Vicencio, José Miguel; Jaimovich Pérez, Enrique; Lavandero González, Sergio (Elsevier, 2014)
      Insulin-like growth factor 1 (IGF-1) signaling regulates contractility, metabolism, hypertrophy, autophagy, senescence, and apoptosis in the heart. IGF-1 deficiency is associated with an increased risk of cardiovascul ...