Browsing by Title Facultad de Ciencias Químicas y Farmacéuticas

Now showing items 3242-3261 of 4844

    • New heterobimetallic ferrocenyl derivatives are promising antitrypanosomal agents 
      Rodríguez Arce, Esteban; Putzu, Eugenia; Lapier, Michel; Maya Arango, Juan; Olea Azar, Claudio; Echeverría, Gustavo A.; Piro, Oscar E.; Medeiros, Andrea; Sardi, Florencia; Comini, Marcelo; Risi, Gastón; Salinas, Gustavo; Correia, Isabel; Pessoa, João Costa; Otero, Lucía (Royal Society of Chemistry, 2019)
      In the search for a more effective chemotherapy for the treatment of Chagas' disease and human African trypanosomiasis, caused by Trypanosoma cruzi and Trypanosoma brucei parasites, respectively, the use of organometallic ...
    • New heterocyclic skeletons derived from the aporphine alkaloid boldine 
      Sobarzo Sánchez, Eduardo; Saitz Barría, Claudio; Jullian Matthaei, Carolina; Cassels Niven, Bruce (MARCEL DEKKER INC, 2002)
      The abundant aporphine alkaloid (S)-(+)-boldine (1) was selectively nitrosated with sodium nitrite in acetic acid affording 8-nitrosoboldine (2) which was hydrogenated catalytically to give 8-aminoboldine (3). The latter ...
    • New Highly Charged Iron(III) Metal−Organic Cube Stabilized by a Bulky Amine 
      Cruz, Carlos; Vega Carvallo, Andrés Igor; Spodine, Evgenia; Escuer, Albert; Marco, José F.; Menéndez, Nieves; Venegas Yazigi, Diego; Paredes García, Verónica (American Chemical Society, 2020)
      In this work, we report a new octanuclear cluster based on FeIII and the ligand 1H-imidazole-4,5-dicarboxylic acid, [Et3NH](12)[Fe-8(IDC)(12)]center dot 10DMF center dot 13H(2)O (1), with a metal core containing eight ...
    • New Hybrid Nanocomposites with Catalytic properties obtained by In situ preparation of gold nanoparticles ... 
      Ramírez, Oscar; Leal, Matías; Briones Olaran, Ximena Gabriela; Urzúa Acevedo, Marcela del Pilar; Bonardd, Sebastián; Saldías, César; Leiva, Angel (MDPI, 2022)
      In this work, we report the obtaining of new hybrid nanocomposites with catalytic activity formed by nanofibers of polymer blends and gold nanoparticles. The nanofibers were obtained by electrospinning blends of a poly ...
    • New idea for the topological index evaluation and treatise multiple regression with three independent ... 
      Cornwell, E. (SOCIEDAD CHILENA DE QUIMICA, 2006-03)
      In QSRR discipline an easy novel to used parameter was designed (Vc) for evaluated classical topological index (W, (1)chi, Z, MTI) and two new generation ones (Xu, (1)chi(h)). Regression between Vc and (1)chi(h) presented ...
    • New insights into IGF-1 signaling in the heart 
      Troncoso Cotal, Rodrigo Hernán; Ibarra, Cristián; Vicencio, José Miguel; Jaimovich Pérez, Enrique; Lavandero González, Sergio (Elsevier, 2014)
      Insulin-like growth factor 1 (IGF-1) signaling regulates contractility, metabolism, hypertrophy, autophagy, senescence, and apoptosis in the heart. IGF-1 deficiency is associated with an increased risk of cardiovascul ...
    • New molecular and organelle alterations linked to down syndrome heart disease 
      Venegas Zamora, Leslye Paola; Bravo Acuña, Francisco Javier; Sigcho Garrido, Francisco Javier; Gómez Calderón, Wileidy; Bustamante Salazar, José Brayan; Pedrozo Cibils, Zully; Parra Ortiz, Valentina María (Frontiers Media, 2022)
      Down syndrome (DS) is a genetic disorder caused by a trisomy of the human chromosome 21 (Hsa21). Overexpression of Hsa21 genes that encode proteins and non-coding RNAs (ncRNAs) can disrupt several cellular functions and ...
    • New Molecular Insights of Insulin in Diabetic Cardiomyopathy 
      Westermeier, Francisco; Riquelme, Jaime A.; Pavez, Mario; Garrido, Valeria; Díaz, Ariel; Verdejo, Hugo E.; Castro, Pablo F.; García Nannig, Lorena; Lavandero González, Sergio (Frontiers Media S.A., 2016-04)
      Type 2 diabetes mellitus (T2DM) is a highly prevalent disease worldwide. Cardiovascular disorders generated as a consequence of T2DM are a major cause of death related to this disease. Diabetic cardiomyopathy (DCM) is ...
    • New organoruthenium complexes with bioactive thiosemicarbazones as co-ligands: potential anti-trypanosomal agents 
      Demoro, Bruno; Sarniguet, Cynthia; Sánchez Delgado, Roberto; Rossi, Miriam; Liebowitz, Daniel; Caruso, Francesco; Olea Azar, Claudio; Moreno, Virtudes; Medeiros, Andrea; Comini, Marcelo A.; Otero, Lucía; Gambino, Dinorah (ROYAL SOC CHEMISTRY, 2012)
      In the search for new therapeutic tools against neglected diseases produced by trypanosomatid parasites, and particularly against African Trypanosomiasis, whose etiological agent is Trypanosoma brucei, organoruthenium ...
    • New phenolic esters from the resinous exudate of Haplopappus taeda 
      Faini, Francesca; Labbé, Cecilia; Torres, René; Rodilla, Jesús M.; Silva, Lucía; Monache, Franco Delle (2007)
      Two new phenolic esters 9-trans-p-coumaroyloxy-α-terpineol (1) and 7-trans-p-coumaroyloxy-taedol (2), both endowed with free radical scavenger activity and cleroda-3,13 (E)-dien-15,18-diol (3) for which a cis stereochemistry ...
    • New polynuclear carbonyl ruthenium (II) complexes derived from 1,8-naphthyridine 
      Gajardo, Juana; Araya, Juan C.; Moya, Sergio A.; Pardey, Alvaro J.; Guerchais, Veroniqué; Le Bozec, Hubert; Aguirre, Pedro (2006)
      This work shows the synthesis and characterization of new carbonyl complexes derived of 1,8-naphthyridine. Covalently bonded complex can be successfully employed in building of supramolecular structures. Copyright © 2005 ...
    • New polynuclear carbonyl ruthenium(II) complexes derived from 1,8-naphthyridine 
      Gajardo, Juana; Araya, Juan Carlos; Moya, Sergio A.; Pardey, Alvaro J.; Guerchais, Veronique; Le Bozec, Hubert; Aguirre Álvarez, Pedro (JOHN WILEY & SONS, 2006-04)
      This work shows the synthesis and characterization of new carbonyl complexes derived of 1,8-naphthyridine. Covalently bonded complex can be successfully employed in building of supramolecular structures.
    • New potent 5-nitroindazole derivatives as inhibitors of Trypanosoma cruzi growth: Synthesis, biological ... 
      Rodríguez Borges, Jorge; Arán, Vicente J.; Boiani, Lucía; Olea Azar, Claudio; Lavaggi, María Laura; González, Mercedes; Cerecetto, Hugo; Diego Maya, Juan; Carrasco Pozo, Catalina; Speisky Cosoy, Hernán (PERGAMON-ELSEVIER SCIENCE LTD, 2009-12-15)
      New 5-nitroindazole derivatives were developed and their antichagasic properties studied. Eight compounds (14-18, 20, 26 and 28) displayed remarkable in vitro activities against Trypanosoma cruzi (T. cruzi). Its unspecific ...
    • New pyridone-based derivatives as cannabinoid receptor type 2 agonists 
      Faúndez Parraguez, Manuel; Alarcón Miranda, Carlos; Cho, Young Hwa; Pessoa Mahana, Hernan Armando; Gallardo Garrido, Carlos; Chung, Hery; Faúndez, Mario; Pessoa Mahana, David (MDPI, 2021)
      The activation of the human cannabinoid receptor type II (CB2R) is known to mediate analgesic and anti-inflammatory processes without the central adverse effects related to cannabinoid receptor type I (CB1R). In this work ...
    • New quaternary alkali metal, rare earth (3+) thiophosphate, K2SmP2S7 with both [P2S6]4 and [PS4]3 anions 
      Manríquez Castro, Víctor; Galdámez Silva, Antonio; Guzmán Águila, Daniela (Elsevier, 2008)
      A new quaternary alkali metal, rare earth thiophosphate was synthesized by the ceramic method and characterized by single crystal X-ray diffraction: K2SmP2S7 crystallizes in the monoclinic space group C2 (no. 5) with the ...
    • New quinone antibiotics against methicillin-resistant S. aureus 
      Campanini Salinas, Javier Andrés; Andrades Lagos, Juan Andrés; Hinojosa Torres, Nicolás Antonio; Moreno Ruz, Fabián Eduardo; Alarcón, Pedro; González Rocha, Gerardo; Burbulis, Ian E.; Vásquez Velásquez, David (MDPI, 2021)
      There is an urgent need for the development of new antibiotics. Here, we describe the inhibitory activity of new quinone compounds against methicillin-resistant Staphylococcus aureus (ATCC(R) 43300), methicillin-sensitive ...
    • A new rotating-disk sorptive extraction mode, with a copolymer of divinylbenzene and N-vinylpyrrolidone ... 
      Cañas, Alejandro; Valdebenito, Samuel; Richter Duk, Pablo (Microextraction Techniques, 2014)
      A novel extraction approach was developed based on rotating-disk sorptive extraction (RDSE). In this approach the rotating-disk extraction device consists of a Teflon disk, with a cavity that is loaded with a commercial ...
    • New side chain LC polysiloxanes with carbonyl-bound chiral terminal group 
      Kozlovsky, M. V.; Soto Bustamante, Eduardo; Haase, W. (TAYLOR & FRANCIS LTD, 1996-01)
      A synthetic route has been developed to a new series of homo- and co-polysiloxanes with a terminal chiral 2-(S)-butyl fragment attached to the mesogenic biphenyl core via the ketone binding group, >C=O. The synthesis, ...
    • A new species of Lilloiconcha Weyrauch, 1965 (Pulmonata: Charopidae) from central Chile 
      Araya, Juan Francisco; Aliaga, Juan Antonio (Magnolia Press, 2015)
    • New synthesis of naphtho- and benzoxazoles: Decomposition of naphtho- and benzoxazinones with KOH 
      Saitz Barría, Claudio; Rodríguez, H.; Márquez, Amelia; Cañete, Alvaro; Jullian Matthaei, Carolina; Zanocco Loyola, Antonio (MARCEL DEKKER INC, 2001)
      A method that allows the synthesis of 4 different heterocyclic systems of fused aryl oxazoles, i.e., naphtho[1,2-d], naphtho[2,1-d], naphtho[2,3-d], and benzo[d]oxazoles in reasonable yield is del scribed. This method ...