Now showing items 3262-3281 of 4836

    • Paredes, Aaron J.; Naranjo-Palma, Tatiana; Alfaro-Valdés, Hilda M.; Barriga, Andrés; Babul Cattán, Jorge; Wilson, Christian A.M. (Academic Press Inc., 2017)
      © 2016 Elsevier Inc.DNA staining in gels has historically been carried out using silver staining and fluorescent dyes like ethidium bromide and SYBR Green I (SGI). Using fluorescent dyes allows recovery of the analyte, but ...
    • Barrientos, C; Navarrete-Encina, P.A.; Carbajo, J.; Squella Serrano, Juan (Springer, 2018)
      Here, we reveal a different way of doing the voltammetric experiments that considers the electroactive species packaged in the electrodic phase instead of dissolved in solution. In this way, it is possible to obtain ...
    • Rodríguez Llamazares, Saddys; Merchán, Juan; Olmedo, Ivonne; Marambio, Héctor; Muñoz, Juan; Jara, Paul; Sturm, Juan; Chornik, Boris; Peña, Octavio; Yutronic Sáez, Nicolás; Kogan Bocian, Marcelo (2008)
      A new synthesis and stabilization method was developed for paramagnetic nanoparticles composed of nickel and nickel oxides. Nickel/nickel oxides nanoparticles were synthesized by a method based on ligand displacement of ...
    • Castillo, C.; Seguin, K.; Aguirre Álvarez, Pedro; Venegas Yazigi, Diego; Viegas, A. D. C.; Spodine Spiridonova, Evgenia; Paredes García, Verónica (Royal Soc Chemistry, 2015)
      In this study, we are reporting the synthesis and characterization of nanocomposites obtained from the direct reduction of nickel(II) salts on matrices of polyethylene (Pe) and chitosan (Ch) in the presence of serine ...
    • Cáceres Jensen, Lizethly; Rodríguez Becerra, Jorge; Escudey, Mauricio; Joo-Nagata, Jorge; Villagra, Cristian A.; Domínguez Vera, Valentina; Neira Albornoz, Angelo; Cornejo Huentemilla, Maribel (Elsevier, 2020)
      Nicosulfuron sorption/desorption kinetics were studied through batch sorption studies in ten volcanic ash-derived Andisol and Ultisol soils with acidic pH and variable surface charge. Two different kinetic models were used ...
    • Pizarro Urzúa, Nancy A.; Núñez Vergara, Luis (ELSEVIER SCIENCE SA, 2005-10-31)
      The ability to generate singlet molecular oxygen, O-2((1)Delta(g)), and the scavenging activity of two well-known 1,4-dihydropyridines (1,4-DHPs) such as nifedipine (1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridin ...
    • Squella Serrano, Juan; Barnafi, E.; Perna, S.; Núñez Vergara, Luis (1989)
      A method for the differential-pulse polarographic determination of nifedipine has been developed, based on the electrochemistry of the aromatic nitro group in the drug. Polarography has also been used in studies of the ...
    • Sánchez, G.; Liberona, Leonel; Llanos Mansilla, Jorge; Sanhueza, E. M.; Giussani, Dino A.; Blanco, C. E.; Hanson, M. A.; Riquelme González, Raquel (CAMBRIDGE UNIV PRESS, 2002-10-01)
      The hypothesis that nitric oxide plays a key role in the regulation of adrenal blood flow and plasma concentrations of cortisol and catecholamines under basal and hypoxaemic conditions in the llama fetus was tested. At ...
    • Galleguillos, Marco; Valenzuela Pedevila, María Antonieta; Riquelme González, Raquel; Sanhueza, Emilia M.; Sánchez, Gina; Figueroa, Jorge P.; Llanos Mansilla, Jorge (ELSEVIER SCIENCE INC, 2001-06)
      The fetal llama (Lama glama; a species adapted to live in chronic hypoxia in the highlands of the Andes) did not increase cerebral blood flow and reduce the brain oxygen uptake during hypoxemia. Although nitric oxide (NO) ...
    • Núñez Vergara, Luis; Squella Serrano, Juan; Bollo Dragnic, Soledad; Morello Casté, Antonio; Repetto Scaramelli, Yolanda; Aldunate, Jorge; Letelier, María E. (1997)
      A series of nitro aryl 1,4-dihydropyridine derivatives produced inhibition of both cell growth and oxygen consumption on Tulahuen and LQ strains, and clone Dm 28c of epimastigotes of Trypanosoma cruzi. Nicardipine was found ...
    • Núñez Vergara, Luis; Aldunate, Jorge; Letelier Muñoz, María Eugenia; Bollo Dragnic, Soledad; Repetto Scaramelli, Yolanda; Morello Casté, Antonio; Spencer, P. L.; Squella Serrano, Juan (Elsevier, 1995)
      The cyclic voltammetric (CV) behaviour of nifurtimox was studied. The addition of aprotic solvent (DMF) to nifurtimox in an aqueous citrate buffer system was examined. Qualitatively this results in separation of the initial ...
    • Argüello da Silva, Jacqueline; Núñez Vergara, Luis; Bollo Dragnic, Soledad; Squella Serrano, Juan (ELSEVIER SCIENCE SA, 2006-09)
      Three new nitrofuryl substituted 1,4-dihydropyridine derivatives were electrochemically tested in the scope of newly found compounds useful as chemotherapeutic alternative to the Chagas' disease. All the compounds were ...
    • Bontá, M.; Chauviere, G.; Perie, J.; Núñez Vergara, Luis; Squella Serrano, Juan (PERGAMON-ELSEVIER SCIENCE, 2002-09-25)
      We have studied the electrochemical reduction of some nitroimidazoles such as megazol(2-amino-5-(1-methyl-5-nitro-2-imidazolyl)-1,3,4-thiadiazol, CAS 19622-55-0) and two related derivatives in aprotic media (100% DMF, 0.1 ...
    • Molina Berríos, Alfredo Enrique (Universidad de ChilePrograma Cybertesis, 2007)
      Las 1,4-dihidropiridinas (DHPs) usadas en el tratamiento de enfermedades cardiovasculares, son antagonistas de canales de calcio y además son agentes antioxidantes. Estos fármacos, son metabolizados a través del sistema ...
    • Letelier Muñoz, María Eugenia; Entrala Alrruiz, Paz Andrea; López Alarcón, Camilo; González Lira, Víctor; Molina Berríos, Alfredo Enrique; Cortés Troncoso, Juan; Jara Sandoval, José; Santander, P.; Núñez Vergara, Luis (PERGAMON-ELSEVIER SCIENCE, 2007-12)
      1,4-Dihydropyridines (DHPs) used in the treatment of cardiovascular diseases, are calcium channel antagonists and also antioxidant agents. These drugs are metabolized through cytochrome P-450 oxidative system, majority ...
    • Urzúa, J.; Yañez, C.; Carbajo, J.; Mozo, J. D.; Squella Serrano, Juan (Elsevier, 2020)
      We describe nanostructured electrode platforms composed of multiwalled carbon nanotube/glassy carbon electrodes (MWCNT/GCEs) with entrapped nitroaromatic compounds such as 2-nitrofluorene (2-NF), 2-nitro-9- fluorenone ...
    • Gallardo Garrido, C.; Cho, Y.; Cortés Ríos, J.; Vásquez Velásquez, David; Pessoa Mahana, C. David; Araya Maturana, R.; Pessoa Mahana, Hernán; Faúndez, M. (Elsevier, 2020)
      Nitrofurans (5-nitro-2-hydrazonylfuran as pharmacophore) are a group of widely used antimicrobial drugs but also associated to a variety of side effects. The molecular mechanisms that underlie the cytotoxic effects of ...
    • Otero, Lucía; Aguirre, Gabriela; Boiani, Lucía; Denicola, Ana; Rigol Olsen, Carolina; Olea Azar, Claudio; Maya Arango, Juan; Morello Casté, Antonio; González, Mercedes; Gambino, Dinorah; Cerecetto, Hugo (ELSEVIER, 2006-11)
      Rhenium and ruthenium complexes of the type [(ReOCl2)-O-V(PPh3)L] and [(RuC2)-C-II(DMSO)(2)L], where L are 5-nitroftitylsemicarbazone derivatives, were prepared in an effort to obtain new anti-trypanosomal agents combining ...
    • Barriga González, Germán Eduardo; Aliaga, Carolina; Olea Azar, Claudio; Zúniga López, María C.; González, Mercedes; Cerecetto, Hugo (Bentham Science Publishers Ltd., 2017)
      Background: Nowadays, nitrones are the most used spin traps to characterize free radicals in biological systems due to the versatility and variety depending on the types of radicals to study and that the half-lives of the ...
    • Merino, M.; Carbajo, J.; Núñez Vergara, Luis; Squella Serrano, Juan (SOCIEDAD CHILENA DE QUIMICA, 2000-03)
      The electrochemical nitroreduction of nitrofurantoin has been studied on carbon paste and glassy carbon electrodes. We can observe a monoelectronic reversible couple ArNO2/ArNO2- and an irreversible peak due to the further ...