Now showing items 2437-2456 of 4735

    • Jiménez Rubilar, José Manuel (Universidad de Chile, 2011)
      La Enfermedad de Alzheimer (EA) es una enfermedad neurodegenerativa, de evolución lenta y que se caracteriza por ser la forma más común de demencia. En el transcurso de la EA, la proteína tau comienza a hiperfosforilarse ...
    • Sapag Muñoz de la Peña, Amalia; Irarrázaval Aguilera, Thergiorg; Lobos González, Lorena; Muñoz Brauning, Carlos; Quintanilla González, María Elena; Tampier de Jong, Lutske (Nature Publishing Group, 2016)
      Ribozyme genes were designed to reduce voluntary alcohol drinking in a rat model of alcohol dependence. Acetaldehyde generated from alcohol in the liver is metabolized by the mitochondrial aldehyde dehydrogenase (ALDH2) ...
    • Cancino Rivera, Patricio Antonio; Astudillo, Luis; Rovirosa, Juana; San Martín Barrientos, Aurelio (1987)
    • Zapata Urzúa, Claudio; Pérez Ortiz, Magdalena; Acosta, Gerardo A.; Mendoza, Joan; Yedra, Lluis; Estradé, Sonia; Álvarez Lueje, Alejandro; Núñez Vergara, Luis; Albericio, Fernando; Lavilla, Rodolfo; Kogan Bocian, Marcelo (Elsevier, 2015)
      Anisotropic and branched gold nanoparticles have great potential in optical, chemical and biomedical applications. However their syntheses involve multi-step protocols and the use of cytotoxic agents. Here, we report a ...
    • Castro Montero, Eduardo (2010)
      Esta recopilación es de los trabajos realizados en el Proyecto FIA “Desarrollo de harina de quínoa orgánica de alta calidad como una alternativa de consumo y de producción sustentable” bajo la dirección del que suscribe y ...
    • Calderón Bravo, Héctor Matías (Universidad de Chile, 2022)
      Una de las principales motivaciones para los consumidores al momento de adquirir sus alimentos es que además de aportar nutrientes, su consumo debe estar relacionado con algún beneficio a la salud. La fibra dietética es ...
    • Yañez Valdés, María Francisca (2014)
      We present a unified approach to the study of Radon transforms related to symmetric groups and to general linear groups GLn(q), regarded as q−analogues of the former. In both cases, we define a sequence of generalized ...
    • Toledo, Carla; Enríquez, Pedro; Garrido, Mariano; Fernández-Band, Beatríz; Richter Duk, Pablo (TAYLOR & FRANCIS INC, 2010)
      A headspace-mass spectrometry with alternative chromatographic separation using a column switching system was developed for the screening and confirmation of BTEX and styrene in comestible oils. According to the position ...
    • García, Vivian; Uribe, Elsa; Vega Gálvez, Antonio; Delporte Vergara, Carla; Valenzuela Barra, Gabriela; López, Jéssica; Pasten, Alexis (Sociedad Chilena de Nutrición, 2020)
      The aim of this study was to evaluate the antioxidant, antidiabetic, anti-inflammatory and antimicrobial activities of three edible seaweed extracts from Chilean coasts: Pyropia orbicularis, Ulva spp, and Durvillaea ...
    • Riedel, Clement; Gabizon, Ronen; Wilson Moya, Christian; Hamadani, Kambiz; Tsekouras, Konstantinos; Marqusee, Susan; Presse, Steve; Bustamante, Carlos (Macmillan, 2015)
      Recent studies have shown that the diffusivity of enzymes increases in a substrate-dependent manner during catalysis1,2. Although this observation has been reported and characterized for several different systems3–10, ...
    • Schalscha B., Eduardo; Ahumada Torres, Aída Inés de Lourdes (PERGAMON-ELSEVIER SCIENCE LTD, 1998)
      Industrial and domestic waste waters in Chile are discharged without previous treatment into rivers and other inland waters which are used to irrigate agricultural lands. The present study reports on results obtained when ...
    • Valenzuela, Manuel A.; Canales, Jimena; Corvalán, Alejandro H.; Quest, Andrew F. G. (Baishideng Publishing Group Inc., 2015)
      The sequence of events associated with the development of gastric cancer has been described as "the gastric precancerous cascade". This cascade is a dynamic process that includes lesions, such as atrophic gastritis, ...
    • Salas Castro, Daniela Paz (Universidad de ChileCyberDocs, 2009)
      El correcto funcionamiento celular requiere condiciones físicas específicas, como pH, temperatura y fuerza iónica. Cualquier alteración de estos parámetros puede producir consecuencias graves para las células. La mantención ...
    • Calderón, Inés; Lobos, S.; Mora, Guido C. (Springer-Verlag, 1984)
      Two outer membrane proteins of Salmonella typhi T y 2 were extensively co-purified. According to their migration in dodecyl sulfate/polyacrylamide gel electrophoresis and solubility characteristics, these proteins are ...
    • Olivares Silva, Francisco Javier; Landaeta, Rodolfo; Aránguiz, Pablo; Bolivar, Samir; Humeres Martínez, Claudio; Anfossi, Renatto; Vivar Sánchez, Raúl; Boza Fuentes, Pía; Muñoz Jofré, Claudia; Pardo Jiménez, Viviana Gladys; Peiro, Concepción; Sánchez Ferrer, Carlos; Díaz Araya, Guillermo (Elsevier, 2018)
      Cardiac fibroblasts (CF) act as sentinel cells responding to chemokines, cytokines and growth factors released in cardiac tissue in cardiac injury events, such as myocardial infarction (MI). Cardiac injury involves the ...
    • Landaeta Millar, Rodolfo Ignacio (Universidad de Chile, 2015)
      Los fibroblastos cardíacos (FC) se encargan de mantener tanto la estructura como la mecánica y la señalización del corazón. A estas células se les conoce como células centinela, pues responden de manera variada y compleja ...
    • Olivares Silva, Francisco Javier (Universidad de Chile, 2016)
      Los fibroblastos cardíacos (FC) son considerados células centinelas del tejido cardíaco, por su compleja y variada respuesta en la mantención de la homeostasis o frente a un evento de injuria cardíaca, como infarto al ...
    • Mena, Natalia P.; Esparza, Andrés; Tapia, Victoria; Valdés, Pamela; Núñez González, Marco (2007)
      Hepcidin (Hepc) is considered a key mediator in iron trafficking. Although the mechanism of Hepc action in macrophages is fairly well established, much less is known about its action in intestinal cells, one of the main ...
    • Letelier, María E.; Iturra Montecinos, Pablo; Gallardo Garrido, Carlos (Universidad de Santiago de Chile, 2017)
      Inflammation is a cellular defensive mechanism associated to oxidative stress. The administration of nitrofurantoin, nifurtimox and acetaminophen generates oxidative stress by their biotransformation through CYP450 system. ...
    • Paredes, Felipe; Parra, Valentina; Torrealba, Natalia; Navarro Márquez, Mario F.; Gatica, Damián; Bravo Sagua, Roberto; Troncoso, Rodrigo; Pennanen, Christian; Quiroga, Clara; Chiong Lay, Mario; Caesar, Christa; Taylor, W. Robert; Molgó, Jordi; San Martín, Alejandra; Jaimovich Pérez, Enrique; Lavandero González, Sergio (Elsevier, 2016)
      Homocysteine-inducible, endoplasmic reticulum (ER) stress-inducible, ubiquitin-like domain member 1 (HERPUD1), an ER resident protein, is upregulated in response to ER stress and Ca2(+) homeostasis deregulation. HERPUD1 ...